Effectiveness of a Pharmacist-Led Drug Counseling on Enhancing Antihypertensive Adherence and Blood Pressure Control: A Randomized Controlled Trial

Adherence to antihypertensive medications represents a crucial success factor for optimal blood pressure (BP) control in clinical practice. This study evaluated whether an additional pharmacist‐led medication counseling could achieve better optimal BP control and enhance compliance. In a designated...

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Bibliographic Details
Published in:	Journal of clinical pharmacology Vol. 53; no. 7; pp. 753 - 761
Main Authors:	Wong, Martin C.S., Liu, Kirin Q.L., Wang, Harry H.X., Lee, Catherine L.S., Kwan, Mandy W.M., Lee, Ken W.S., Cheung, Yu, Lee, Gabrielle K.Y., Morisky, Donald E., Griffiths, Sian M.
Format:	Journal Article
Language:	English
Published:	England Blackwell Publishing Ltd 01-07-2013 American College of Clinical Pharmacology Wiley Subscription Services, Inc
Subjects:	adherence antihypertensive Antihypertensive Agents - administration & dosage Blood pressure Blood Pressure - drug effects clinical practice Compliance Counseling Family Practice Female Hong Kong Humans Hypertension - drug therapy Male Medication Adherence medication counseling Middle Aged pharmacist intervention Pharmacists Hong Kong
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Summary:	Adherence to antihypertensive medications represents a crucial success factor for optimal blood pressure (BP) control in clinical practice. This study evaluated whether an additional pharmacist‐led medication counseling could achieve better optimal BP control and enhance compliance. In a designated family clinic in a region with similar resident characteristics to Hong Kong, patients taking ≥ one antihypertensive agent with suboptimal compliance were randomly allocated to a brief 3‐minute drug advice (control; n = 161) or pharmacist counseling (intervention; n = 113). The two groups were compared by repeated measure ANOVA at 3‐months and 6‐months with BP control and medication compliance as outcome variables, respectively. The proportions of patients having optimal compliance increased from 0% to 41.1% at 3 months and 61.9% at 6 months (P < 0.001). The proportion of patients having optimal BP control improved from 64.1% at baseline to 74.0% at 3 months and 74.5% at 6 months (P = 0.023). There were no significant differences between the two groups in the changes of BP control and compliance levels. This study implied that even a brief 3‐minute drug advice might lead to improved BP levels among patients on antihypertensive medications in general practice, but did not demonstrate additional effects by pharmacist counseling.
Bibliography:	ark:/67375/WNG-BRZR4V7R-N istex:B75BEB32C5673B0EAC91E51E7489285E913EABFA ArticleID:JCPH101 ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-News-1 ObjectType-Feature-3 content type line 23
ISSN:	0091-2700 1552-4604
DOI:	10.1002/jcph.101