Search Results - "Lee, Joo Y"

Direct Binding to NLRP3 Pyrin Domain as a Novel Strategy to Prevent NLRP3‐Driven Inflammation and Gouty Arthritis by Yang, Gabsik, Lee, Hye E., Moon, Su‐Jin, Ko, Kyung M., Koh, Jung H., Seok, Jin K., Min, Jun‐Ki, Heo, Tae‐Hwe, Kang, Han C., Cho, Yong‐Yeon, Lee, Hye S., Fitzgerald, Katherine A., Lee, Joo Y.

“…Objective The NLRP3 inflammasome is closely linked to the pathophysiology of a wide range of inflammatory diseases. This study was undertaken to identify small…”
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Modulation of pattern recognition receptor-mediated inflammation and risk of chronic diseases by dietary fatty acids by Lee, Joo Y, Zhao, Ling, Hwang, Daniel H

“…Chronic inflammation is known to promote the development of many chronic diseases. Pattern recognition receptors (PRRs), Toll‐like receptors (TLRs), and…”
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Inhibition of pattern recognition receptor-mediated inflammation by bioactive phytochemicals by Zhao, Ling, Lee, Joo Y, Hwang, Daniel H

“…Emerging evidence reveals that pattern‐recognition receptors (PRRs), Toll‐like receptors (TLRs), and nucleotide‐binding oligomerization domain proteins (NODs)…”
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Differential modulation of Toll-like receptors by fatty acids: preferential inhibition by n-3 polyunsaturated fatty acids by Lee, Joo Y, Plakidas, Anthony, Lee, Won H, Heikkinen, Anne, Chanmugam, Prithiva, Bray, George, Hwang, Daniel H

“…Human subjects consuming fish oil showed a significant suppression of cyclooxygenase-2 (COX-2) expression in blood monocytes when stimulated in vitro with…”
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Saturated and Polyunsaturated Fatty Acids Reciprocally Modulate Dendritic Cell Functions Mediated through TLR4 by Weatherill, A.R, Zhao, L, Lemay, D.G, Youn, H.S, Hwang, D.H

“…TLRs provide critical signals to induce innate immune responses in APCs such as dendritic cells (DCs) that in turn link to adaptive immune responses. Results…”
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Specific Inhibition of MyD88-Independent Signaling Pathways of TLR3 and TLR4 by Resveratrol: Molecular Targets Are TBK1 and RIP1 in TRIF Complex by Youn, H.S, Fitzgerald, K.A, Young, H.A, Akira, S, Hwang, D.H

“…TLRs can activate two distinct branches of downstream signaling pathways. MyD88 and Toll/IL-1R domain-containing adaptor inducing IFN-beta (TRIF) pathways lead…”
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Magnolin targeting of ERK1/2 inhibits cell proliferation and colony growth by induction of cellular senescence in ovarian cancer cells by Song, Ji‐Hong, Lee, Cheol‐Jung, An, Hyun‐Jung, Yoo, Sun‐Mi, Kang, Han C., Lee, Joo Y., Kim, Kwang D., Kim, Dae J., Lee, Hye S., Cho, Yong‐Yeon

“…Ras/Raf/MEKs/ERKs and PI3 K/Akt/mTOR signaling pathways have key roles in cancer development and growth processes, as well as in cancer malignance and…”
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Reciprocal Modulation of Toll-like Receptor-4 Signaling Pathways Involving MyD88 and Phosphatidylinositol 3-Kinase/AKT by Saturated and Polyunsaturated Fatty Acids by Lee, Joo Y., Ye, Jianping, Gao, Zhanguo, Youn, Hyung S., Lee, Won H., Zhao, Ling, Sizemore, Nywana, Hwang, Daniel H.

“…Toll-like receptor-4 (TLR4) can be activated by nonbacterial agonists, including saturated fatty acids. However, downstream signaling pathways activated by…”
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Suppression of MyD88- and TRIF-dependent signaling pathways of toll-like receptor by (−)-epigallocatechin-3-gallate, a polyphenol component of green tea by Youn, Hyung S., Lee, Joo Y., Saitoh, Shin I., Miyake, Kensuke, Kang, Keon W., Choi, Yong J., Hwang, Daniel H.

“…Toll-like receptors (TLRs) play an important role in recognition of microbial components and induction of innate immunity. The microbial components trigger the…”
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Saturated Fatty Acid Activates but Polyunsaturated Fatty Acid Inhibits Toll-like Receptor 2 Dimerized with Toll-like Receptor 6 or 1 by Lee, Joo Y., Zhao, Ling, Youn, Hyung S., Weatherill, Amy R., Tapping, Richard, Feng, Lili, Lee, Won H., Fitzgerald, Katherine A., Hwang, Daniel H.

“…Toll-like receptor 4 (TLR4) and TLR2 agonists from bacterial origin require acylated saturated fatty acids in their molecules. Previously, we reported that…”
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Differential Modulation of Nods Signaling Pathways by Fatty Acids in Human Colonic Epithelial HCT116 Cells by Zhao, Ling, Kwon, Myung-Ja, Huang, Shurong, Lee, Joo Y., Fukase, Koichi, Inohara, Naohiro, Hwang, Daniel H.

“…Nucleotide-binding oligomerization domain-containing proteins (Nods) are intracellular pattern recognition receptors recognizing conserved moieties of…”
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Methane Disintegration by Water Vapor in a Hot Chamber heated by Using a Microwave Steam Torch by Choi, Chang H., Lee, Joo Y., Kim, Dong J., Woo, Sang G., Uhm, Han S.

“…An analysis of the behaviors of water and methane in a hot chamber indicates that methane and water molecules mutually help to disintegrate each other. Oxygen…”
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Production of Hydrogen-Rich Syngas from Dimethyl Ether by Using a Microwave Steam Plasma by Uhm, Han S., Choi, Chang H., Lee, Joo Y., Kim, Dong J., Woo, Sang G., Woo, Minwoo, Lee, Dong C.

“…Dimethyl ether (DME) is disintegrated by a microwave steam-plasma raising the gas temperature in a reaction chamber of 100 liters in a swirl-type gasifier…”
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The modulation of inflammatory gene expression by lipids: mediation through Toll-like receptors by Lee, Joo Y, Hwang, Daniel H

“…Toll-like receptors (TLRs) were evolved to detect invading pathogens and to induce innate immune responses in order to mount host defense mechanisms. It…”
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Auranofin, as an anti-rheumatic gold compound, suppresses LPS-induced homodimerization of TLR4 by Youn, Hyung S., Lee, Joo Y., Saitoh, Shin I., Miyake, Kensuke, Hwang, Daniel H.

“…Toll-like receptors (TLRs), which are activated by invading microorganisms or endogenous molecules, evoke immune and inflammatory responses. TLR activation is…”
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Virtual commissioning for an Overhead Hoist Transporter in a semiconductor FAB by Lee, Joo Y., Lee, Kwanwoo, Park, Sangchul

“…Presented in the paper is a virtual commissioning methodology for the design and verification of an OHT (Overhead Hoist Transporter), which is a vehicle that…”
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The regulation of the expression of inducible nitric oxide synthase by Src-family tyrosine kinases mediated through MyD88-independent signaling pathways of Toll-like receptor 4 by Lee, Joo Y., Lowell, Clifford A., Lemay, Danielle G., Youn, Hyung S., Rhee, Sang H., Sohn, Kyung H., Jang, Byeong, Ye, Jianping, Chung, Jin H., Hwang, Daniel H.

“…Bacterial lipopolysaccharide (LPS) activates Toll-like receptor 4 (TLR4) leading to the expression of inflammatory gene products. Src-family tyrosine kinases…”
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Saturated Fatty Acids, but Not Unsaturated Fatty Acids, Induce the Expression of Cyclooxygenase-2 Mediated through Toll-like Receptor 4 by Lee, Joo Y., Sohn, Kyung H., Rhee, Sang H., Hwang, Daniel

“…Results from our previous studies demonstrated that activation of Toll-like receptor 4 (Tlr4), the lipopolysaccharide (LPS) receptor, is sufficient to induce…”
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Non-clinical assessment of cell therapy products: the perspective from five Asian countries/regions based on regulatory guidelines and the underpinning rationales by Yoneda, Tomohiro, Choi, Byung H., Gupta, Pawan K., Ho, Chih-Yuan, Tsui, Yat P., Wang, Ling-Mei, Fujiwara, Yukari, Karasawa, Hiroshi, Moriya, Yuu, Bando, Kiyoko, Kamiyama, Yoshiteru, Kanki, Masayuki, Omura, Kou, Watanabe, Takeshi, Bae, Yohan, Chou, Feng-Cheng, Ham, Dong-sik, Lee, Joo Y., Liu, Guangyang, Liu, Yongjun, Ooi, James, Tsurumaki, Yoshie

“…•We conducted a questionnaire on the regulatory guidelines for CTPs.•Respondents from India, China, Korea, Taiwan, and Japan participated.•Differences in…”
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The phosphatidylinositol 3-kinase/Akt pathway negatively regulates Nod2-mediated NF-κB pathway by Zhao, Ling, Lee, Joo Y., Hwang, Daniel H.

“…Nucleotide-binding oligomerization domain containing proteins (Nods) are intracellular pattern recognition receptors (PRRs) that recognize conserved moieties…”
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