Search Results - "Lee, Jong‐Hwa"

Formulation Approaches for Improving the Dissolution Behavior and Bioavailability of Tolvaptan Using SMEDDS by Lee, Jong-Hwa, Lee, Gye-Won

“…Tolvaptan, a selective vasopressin receptor antagonist, is a Class IV agent of Biopharmaceutical Classification System (BCS). To improve bioavailability after…”
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Targeting the Mitochondrial Chaperone TRAP1 Alleviates Vascular Pathologies in Ischemic Retinopathy by Kim, So‐Yeon, Yoon, Nam Gu, Im, Jin Young, Lee, Ji Hye, Kim, Juhee, Jeon, Yujin, Choi, Young Jae, Lee, Jong‐Hwa, Uemura, Akiyoshi, Park, Dong Ho, Kang, Byoung Heon

“…Activation of hypoxia‐inducible factor 1α (HIF1α) contributes to blood‐retinal barrier (BRB) breakdown and pathological neovascularization responsible for…”
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Development and Validation of a Bioanalytical Method for 3'- and 6'-Sialyllactose in Minipig Liver and Kidney Using Liquid Chromatography-Tandem Mass Spectrometry and Its Application to Analysis of Tissue Distribution by Eom, Han Young, Jang, Seok-In, Lee, Jong-Hwa

“…Breast milk contains human milk oligosaccharides (HMOs), including sialyllactose (SL). SL is composed of sialic acid and lactose, and is divided into 3'-SL and…”
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Particulate Matter Elevates Ocular Inflammation and Endoplasmic Reticulum Stress in Human Retinal Pigmented Epithelium Cells by Jeong, Sunyoung, Shin, Eui-Cheol, Lee, Jong-Hwa, Ha, Jung-Heun

“…Because of their exposure to air, eyes can come into contact with air pollutants such as particulate matter (PM), which may cause severe ocular pathologies…”
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Ellagic Acid Prevents Particulate Matter-Induced Pulmonary Inflammation and Hyperactivity in Mice: A Pilot Study by Jeong, Sunyoung, Bae, Sungryong, Shin, Eui-Cheol, Lee, Jong-Hwa, Ha, Jung-Heun

“…The inhalation of fine particulate matter (PM) is a significant health-related environmental issue. Previously, we demonstrated that repeated PM exposure…”
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Cut-Off Value of Voluntary Peak Cough Flow in Patients with Parkinson's Disease and Its Association with Severe Dysphagia: A Retrospective Pilot Study by Lee, Kyeong-Woo, Kim, Sang-Beom, Lee, Jong-Hwa, Kim, Seong-Woo

“…Swallowing and coughing reflexes are both closely associated with airway protection. Peak cough flow (PCF) is associated with dysphagia in several neurogenic…”
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Pharmacokinetics of the phage endolysin-based candidate drug SAL200 in monkeys and its appropriate intravenous dosing period by Jun, Soo Youn, Jung, Gi Mo, Yoon, Seong Jun, Youm, So Young, Han, Hyoung-Yun, Lee, Jong-Hwa, Kang, Sang Hyeon

“…Summary SAL200 is a new phage endolysin‐based candidate drug for the treatment of staphylococcal infections. An intravenous administration study was conducted…”
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Acute effects of 4-EA-NBOMe, 3, 4-DCMP, LY-2183240 and AB-CHFUPYCA on the excitability of rat cortical primary cultured neurons by Oh, Hyun-A, Lee, Jong-Hwa, Woo, Dong Ho

“…Background Various methods to evaluate the effect of new psychoactive substances (NPSs) on the central nervous system (CNS) are available, but they are not…”
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1'-Acetoxychavicol acetate isolated from Alpinia galanga ameliorates ovalbumin-induced asthma in mice by Seo, Joung-Wook, Cho, Soon-Chang, Park, Sang-Joon, Lee, Eun-Ji, Lee, Jong-Hwa, Han, Sang-Seop, Pyo, Byeong Sik, Park, Dae-Hun, Kim, Bong-Hee

“…The World Health Organization reports that 235 million people are currently affected by asthma. This disease is associated with an imbalance of Th1 and Th2…”
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Boron transport through polyamide-based thin film composite forward osmosis membranes by Fam, Winny, Phuntsho, Sherub, Lee, Jong Hwa, Cho, Jaeweon, Shon, Ho Kyong

“…The boron transport in forward osmosis (FO) process using thin film composite (TFC) membranes has been investigated. Two common fertilizers were used as draw…”
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Functional Analysis of the Fructooligosaccharide Utilization Operon in Lactobacillus paracasei 1195 by Goh, Yong Jun, Lee, Jong-Hwa, Hutkins, Robert W

“…The fosABCDXE operon encodes components of a putative fructose/mannose phosphoenolpyruvate-dependent phosphotransferase system and a β-fructosidase precursor…”
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Development and Validation of Analytical Method for SH-1242 in the Rat and Mouse Plasma by Liquid Chromatography/Tandem Mass Spectrometry by Jeong, Yoo-Seong, Baek, Minjeong, Lee, Seungbeom, Kim, Min-Soo, Maeng, Han-Joo, Lee, Jong-Hwa, Suh, Young-Ger, Chung, Suk-Jae

“…SH-1242, a novel inhibitor of heat shock protein 90 (HSP90), is a synthetic analog of deguelin: It was previously reported that the treatment of SH-1242 led to…”
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Kinetics of the Absorption, Distribution, Metabolism, and Excretion of Lobeglitazone, a Novel Activator of Peroxisome Proliferator-Activated Receptor Gamma in Rats by Lee, Jong-Hwa, Noh, Chi-Kyoung, Yim, Chang-Soon, Jeong, Yoo-Seong, Ahn, Sung Hoon, Lee, Wooin, Kim, Dae-Duk, Chung, Suk-Jae

“…This study was performed to determine biopharmaceutical properties of lobeglitazone (LB), a novel thiazolidinedione-based activator of peroxisome…”
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Clinical outcome of biportal endoscopic revisional lumbar discectomy for recurrent lumbar disc herniation by Kang, Min-Seok, Hwang, Jin-Ho, Choi, Dae-Jung, Chung, Hoon-Jae, Lee, Jong-Hwa, Kim, Hyong-Nyun, Park, Hyun-Jin

“…Background Although literature provides evidence regarding the superiority of surgery over conservative treatment in patients with lumbar disc herniation,…”
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Risk Factors for Depressive Symptoms in Korean Adult Stroke Survivors: The Korea National Health and Nutrition Examination Survey IV–VII (2007–2018) by Hong, Min-Woo, Lee, Jong-Hwa, Lee, Kyeong-Woo, Kim, Sang-Beom, Kang, Min-Gu

“…Depressive symptoms are common in stroke survivors, and they are associated with poor outcomes. Therefore, this study aimed to investigate the depressive…”
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Application of physiologically‐based pharmacokinetic model approach to predict pharmacokinetics and drug–drug interaction of rivaroxaban: A case study of rivaroxaban and carbamazepine by Ngo, Lien Thi, Yang, Sung‐yoon, Shin, Sooyoung, Cao, Duc Tuan, Van Nguyen, Hung, Jung, Sangkeun, Lee, Jae‐Young, Lee, Jong‐Hwa, Yun, Hwi‐yeol, Chae, Jung‐woo

“…Rivaroxaban (RIV; Xarelto; Janssen Pharmaceuticals, Beerse, Belgium) is one of the direct oral anticoagulants. The drug is a strong substrate of cytochrome…”
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The Development and Optimization of Hot-Melt Extruded Amorphous Solid Dispersions Containing Rivaroxaban in Combination with Polymers by Lee, Jong-Hwa, Jeong, Hyeong Sik, Jeong, Jong-Woo, Koo, Tae-Sung, Kim, Do-Kyun, Cho, Young Ho, Lee, Gye Won

“…Rivaroxaban (RXB), a novel oral anticoagulant that directly inhibits factor Xa, is a poorly soluble drug belonging to Biopharmaceutics Classification System…”
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Targeting the Mitochondrial Chaperone TRAP1 Alleviates Vascular Pathologies in Ischemic Retinopathy (Adv. Sci. 2/2024) by Kim, So‐Yeon, Yoon, Nam Gu, Im, Jin Young, Lee, Ji Hye, Kim, Juhee, Jeon, Yujin, Choi, Young Jae, Lee, Jong‐Hwa, Uemura, Akiyoshi, Park, Dong Ho, Kang, Byoung Heon

“…Ischemic Retinopathy Ischemic retinopathies exhibit blood‐retinal barrier breakdown and pathological neovascularization, ultimately leading to blindness. In…”
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Long-Term Effects of Extracorporeal Shock Wave Therapy on Breast Cancer-Related Lymphedema by Lee, Jong-Hwa, Kim, Sang-Beom, Lee, Kyeong-Woo, Ha, Won-Wook

“…Extracorporeal shock wave therapy (ESWT) can reduce breast cancer-related lymphedema (BCRL). However, evidence of the long-term effectiveness of ESWT on BCRL…”
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Quantification of venadaparib, a novel PARP inhibitor, in the rat and dog plasma using liquid chromatography/tandem mass spectrometry by Lee, Myongjae, Jang, Eunhye, Lee, Jungwoo, Choi, SungKu, Lee, Won Sik, Baek, Nam Seok, Lee, Sungsook, Park, Young-Whan, Lee, Jong-Hwa, Chung, Suk-Jae

“…Venadaparib (VEN), a next-generation inhibitor of poly (ADP-ribose) polymerases, is under development for oral use in patients having cancers with…”
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