Search Results - "Lee, Jonathan Wei Jie"
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Challenges in Implementing Endoscopic Resection for T2 Colorectal Cancer
Published in Gut and liver (01-03-2024)“…The current standard treatment for muscularis propria-invasive (T2) colorectal cancer is surgical colectomy with lymph node dissection. With the advent of new…”
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Multi-omics reveal microbial determinants impacting responses to biologic therapies in inflammatory bowel disease
Published in Cell host & microbe (11-08-2021)“…The intestinal microbiome is a key determinant of responses to biologic therapy in inflammatory bowel disease (IBD). However, diverse therapeutics and variable…”
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Engineering probiotics to inhibit Clostridioides difficile infection by dynamic regulation of intestinal metabolism
Published in Nature communications (04-07-2022)“…Clostridioides difficile infection (CDI) results in significant morbidity and mortality in hospitalised patients. The pathogenesis of CDI is intrinsically…”
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Mucosal microbiome associates with progression to gastric cancer
Published in Theranostics (2022)“…Dysbiosis is associated with gastric cancer (GC) development. However, no longitudinal study was carried out to identify key bacteria that could predict for GC…”
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Non-obese non-alcoholic fatty liver disease (NAFLD) in Asia: an international registry study
Published in Metabolism, clinical and experimental (01-01-2022)“…A significant proportion of the non-alcoholic fatty liver disease (NAFLD) population is non-obese. Prior studies reporting the severity of NAFLD amongst…”
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Population study of the gut microbiome: associations with diet, lifestyle, and cardiometabolic disease
Published in Genome medicine (17-12-2021)“…The human gut harbors trillions of microbes that play dynamic roles in health. While the microbiome contributes to many cardiometabolic traits by modulating…”
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Identification of age-associated microbial changes via long-read 16S sequencing
Published in Gut pathogens (05-10-2024)“…Age-related gut microbial changes have been widely investigated over the past decade. Most of the previous age-related microbiome studies were conducted on the…”
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The microbial composition and functional roles of different kombucha products in Singapore
Published in CYTA: journal of food (31-12-2023)“…Kombucha is a fermented tea known for its health-enhancing properties owing to the bioactive compounds generated by acetic acid bacteria (AAB) and lactic acid…”
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Asian consensus on the relationship between obesity and gastrointestinal and liver diseases
Published in Journal of gastroenterology and hepatology (01-08-2016)“…The incidence of obesity is increasing in Asia, with implications on gastrointestinal (GI) and liver diseases. The Gut and Obesity in Asia Workgroup comprises…”
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Artificial intelligence–assisted treatment strategy for T1 colorectal cancer after endoscopic resection
Published in Gastrointestinal endoscopy (01-06-2023)Get full text
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“Pathologist-independent” strategy for T1 colorectal cancer after endoscopic resection
Published in Journal of gastroenterology (01-10-2022)Get full text
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Esophageal Melanocytosis in a Patient With Gastroesophagheal Reflux Disease
Published in Clinical gastroenterology and hepatology (01-02-2020)Get full text
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A case report of improvement on ADHD symptoms after fecal microbiota transplantation with gut microbiome profiling pre- and post-procedure
Published in Current medical research and opinion (02-11-2022)“…Recent studies demonstrate the association of the gut microbiome in regulating interactions between the central nervous system and intestinal function…”
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Ex vivo metabolism kinetics of primary to secondary bile acids via a physiologically relevant human faecal microbiota model
Published in Chemico-biological interactions (25-08-2024)“…Bile acids (BA) are synthesized in the human liver and undergo metabolism by host gut bacteria. In diseased states, gut microbial dysbiosis may lead to high…”
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Association of distinct microbial signatures with premalignant colorectal adenomas
Published in Cell host & microbe (10-05-2023)“…Environmental exposures are a major risk factor for developing colorectal cancer, and the gut microbiome may serve as an integrator of such environmental risk…”
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Association of distinct microbial signatures with pre-malignant colorectal adenomas
Published in Cell host & microbe (01-05-2023)“…Environmental exposures are a major risk factor for developing colorectal cancer, and the gut microbiome may serve as an integrator of such environmental risk…”
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Real-World Validation of a Computer-Aided Diagnosis System for Prediction of Polyp Histology in Colonoscopy: A Prospective Multicenter Study
Published in The American journal of gastroenterology (01-08-2023)“…Computer-aided diagnosis (CADx) of polyp histology could support endoscopists in clinical decision-making. However, this has not been validated in a real-world…”
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Artificial Intelligence to Predict the Risk of Lymph Node Metastasis in T2 Colorectal Cancer
Published in Annals of surgery (01-11-2024)“…To develop and externally validate an updated artificial intelligence (AI) prediction system for stratifying the risk of lymph node metastasis (LNM) in T2…”
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