Search Results - "Lee, Jonathan W"

Protecting the front line: a cross-sectional survey analysis of the occupational factors contributing to healthcare workers’ infection and psychological distress during the COVID-19 pandemic in the USA by Firew, Tsion, Sano, Ellen D, Lee, Jonathan W, Flores, Stefan, Lang, Kendrick, Salman, Kiran, Greene, M Claire, Chang, Bernard P

“…ObjectiveThe COVID-19 pandemic has been associated with significant occupational stressors and challenges for front-line healthcare workers (HCWs), including…”
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Phase 1 trial evaluating cisplatin, gemcitabine, and veliparib in 2 patient cohorts: Germline BRCA mutation carriers and wild‐type BRCA pancreatic ductal adenocarcinoma by O'Reilly, Eileen M., Lee, Jonathan W., Lowery, Maeve A., Capanu, Marinela, Stadler, Zsofia K., Moore, Malcolm J., Dhani, Neesha, Kindler, Hedy L., Estrella, Hayley, Maynard, Hannah, Golan, Talia, Segal, Amiel, Salo‐Mullen, Erin E., Yu, Kenneth H., Epstein, Andrew S., Segal, Michal, Brenner, Robin, Do, Richard K., Chen, Alice P., Tang, Laura H., Kelsen, David P.

“…BACKGROUND A phase 1 trial was used to evaluate a combination of cisplatin, gemcitabine, and escalating doses of veliparib in patients with untreated advanced…”
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Infection with pathogenic Blastocystis ST7 is associated with decreased bacterial diversity and altered gut microbiome profiles in diarrheal patients by Deng, Lei, Lee, Jonathan W. J, Tan, Kevin S. W

“…Abstract Background Blastocystis is a common protistan parasite inhabiting the gastrointestinal tract of humans and animals. While there are increasing reports…”
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Grapefruit Juice and Statins by Lee, Jonathan W., BS, Morris, Joan K., PhD, Wald, Nicholas J., FRS

“…Abstract We determined the validity of current medical advice to avoid grapefruit juice consumption while taking 3 widely used statins. A daily glass of…”
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Prevalence and molecular subtyping of Blastocystis in patients with Clostridium difficile infection, Singapore by Deng, Lei, Tay, Huiyi, Peng, Guangneng, Lee, Jonathan W. J, Tan, Kevin S. W

“…Abstract Background Blastocystis is a common anaerobic colonic protist in humans with controversial pathogenicity. Clostridium difficile ( C. difficile ) is…”
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Interleukin-1 receptor antagonist ameliorates the pain hypersensitivity, spinal inflammation and oxidative stress induced by systemic lipopolysaccharide in neonatal rats by Hsieh, Cheng-Ta, Lee, Yih-Jing, Lee, Jonathan W., Lu, Silu, Tucci, Michelle A., Dai, Xiaoli, Ojeda, Norma Beatriz, Lee, Hyun Joon, Fan, Lir-Wan, Tien, Lu-Tai

“…Perinatal inflammation-induced reduction in pain threshold may alter pain sensitivity to hyperalgesia or allodynia which may persist into adulthood. In this…”
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Severity of gastric intestinal metaplasia predicts the risk of gastric cancer: a prospective multicentre cohort study (GCEP) by Lee, Jonathan W J, Zhu, Feng, Srivastava, Supriya, Tsao, Stephen Kk, Khor, Christopher, Ho, Khek Yu, Fock, Kwong Ming, Lim, Wee Chian, Ang, Tiing Leong, Chow, Wan Cheng, So, Jimmy Bok Yan, Koh, Calvin J, Chua, Shijia Joy, Wong, Andrew S Y, Rao, Jaideepraj, Lim, Lee Guan, Ling, Khoon Lin, Chia, Chung-King, Ooi, Choon Jin, Rajnakova, Andrea, Yap, Wai Ming, Salto-Tellez, Manuel, Ho, Bow, Soong, Richie, Chia, Kee Seng, Teo, Yik Ying, Teh, Ming, Yeoh, Khay-Guan

“…To investigate the incidence of gastric cancer (GC) attributed to gastric intestinal metaplasia (IM), and validate the Operative Link on Gastric Intestinal…”
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Pioglitazone Ameliorates Lipopolysaccharide-Induced Behavioral Impairment, Brain Inflammation, White Matter Injury and Mitochondrial Dysfunction in Neonatal Rats by Yeh, Jiann-Horng, Wang, Kuo-Ching, Kaizaki, Asuka, Lee, Jonathan W, Wei, Han-Chi, Tucci, Michelle A, Ojeda, Norma B, Fan, Lir-Wan, Tien, Lu-Tai

“…Previous studies have demonstrated that pioglitazone, a peroxisome proliferator-activated receptor gamma (PPARγ) agonist, inhibits ischemia-induced brain…”
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Functionalized Collagen/Elastin‐like Polypeptide Hydrogels for Craniofacial Bone Regeneration by Pal, Pallabi, Tucci, Michelle A., Fan, Lir‐Wan, Bollavarapu, Ratna, Lee, Jonathan W., Salazar Marocho, Susana M., Janorkar, Amol V.

“…Critical‐sized cranial bone defects fail to re‐ossify and require the surgical intervention of cranioplasty. To achieve superior bone healing in such cases, a…”
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Atomistic and Molecular Effects in Electric Double Layers at High Surface Charges by Lee, Jonathan W, Mani, Ali, Templeton, Jeremy A

“…The Poisson–Boltzmann theory for electrolytes near a charged surface is known to be invalid due to unaccounted physics associated with high ion concentration…”
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Chlorambucil targets BRCA1/2‐deficient tumours and counteracts PARP inhibitor resistance by Tacconi, Eliana MC, Badie, Sophie, De Gregoriis, Giuliana, Reisländer, Timo, Lai, Xianning, Porru, Manuela, Folio, Cecilia, Moore, John, Kopp, Arnaud, Baguña Torres, Júlia, Sneddon, Deborah, Green, Marcus, Dedic, Simon, Lee, Jonathan W, Batra, Ankita Sati, Rueda, Oscar M, Bruna, Alejandra, Leonetti, Carlo, Caldas, Carlos, Cornelissen, Bart, Brino, Laurent, Ryan, Anderson, Biroccio, Annamaria, Tarsounas, Madalena

“…Due to compromised homologous recombination (HR) repair, BRCA1‐ and BRCA2‐ mutated tumours accumulate DNA damage and genomic rearrangements conducive of tumour…”
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Anomalous Optoelectronic Properties of Chiral Carbon Nanorings…and One Ring to Rule Them All by Wong, Bryan M, Lee, Jonathan W

“…Carbon nanorings are hoop-shaped, π-conjugated macrocycles that form the fundamental annular segments of single-walled carbon nanotubes (SWNTs). In a very…”
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Editorial: Microbiome and human host interactions and their implications on human health by Leo, Jazleen, Chong, Chun Wie, Pribowo, Amadeus Yeremia, Sutejo, Richard, Lee, Jonathan W J

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Neuroprotective Effects of Intranasal IGF-1 against Neonatal Lipopolysaccharide-Induced Neurobehavioral Deficits and Neuronal Inflammation in the Substantia Nigra and Locus Coeruleus of Juvenile Rats by Tien, Lu-Tai, Lee, Yih-Jing, Pang, Yi, Lu, Silu, Lee, Jonathan W, Tseng, Chih-Hsueh, Bhatt, Abhay J, Savich, Renate D, Fan, Lir-Wan

“…Neonatal lipopolysaccharide (LPS) exposure-induced brain inflammation resulted in motor dysfunction and brain dopaminergic neuronal injury, and increased the…”
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Intranasal insulin attenuates hypoxia-ischemia-induced short-term sensorimotor behavioral disturbances, neuronal apoptosis, and brain damage in neonatal rats by Talati, Chirag P., Lee, Jonathan W., Lu, Silu, Ojeda, Norma B., Prakash, Varsha, Dankhara, Nilesh, Nielson, Tanner C., Sandifer, Sara P., Bidwell, Gene L., Pang, Yi, Fan, Lir-Wan, Bhatt, Abhay J.

“…There is a significant need for additional therapy to improve outcomes for newborns with acute Hypoxic-ischemic (HI) encephalopathy (HIE). New evidence…”
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Small-area spatio-temporal analyses of bladder and kidney cancer risk in Nova Scotia, Canada by Saint-Jacques, Nathalie, Lee, Jonathan S W, Brown, Patrick, Stafford, Jamie, Parker, Louise, Dummer, Trevor J B

“…Bladder and kidney cancers are the ninth and twelfth most common type of cancer worldwide, respectively. Internationally, rates vary ten-fold, with several…”
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Randomized, Multicenter, Phase II Trial of Gemcitabine and Cisplatin With or Without Veliparib in Patients With Pancreas Adenocarcinoma and a Germline BRCA/PALB2 Mutation by O'Reilly, Eileen M, Lee, Jonathan W, Zalupski, Mark, Capanu, Marinela, Park, Jennifer, Golan, Talia, Tahover, Esther, Lowery, Maeve A, Chou, Joanne F, Sahai, Vaibhav, Brenner, Robin, Kindler, Hedy L, Yu, Kenneth H, Zervoudakis, Alice, Vemuri, Shreya, Stadler, Zsofia K, Do, Richard K G, Dhani, Neesha, Chen, Alice P, Kelsen, David P

“…Five percent to 9% of pancreatic ductal adenocarcinomas (PDACs) develop in patients with a germline or (g +) mutation. Phase IB data from a trial that used…”
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Prospective Evaluation of Germline Alterations in Patients With Exocrine Pancreatic Neoplasms by Lowery, Maeve A, Wong, Winston, Jordan, Emmet J, Lee, Jonathan W, Kemel, Yelena, Vijai, Joseph, Mandelker, Diana, Zehir, Ahmet, Capanu, Marinela, Salo-Mullen, Erin, Arnold, Angela G, Yu, Kenneth H, Varghese, Anna M, Kelsen, David P, Brenner, Robin, Kaufmann, Erica, Ravichandran, Vignesh, Mukherjee, Semanti, Berger, Michael F, Hyman, David M, Klimstra, David S, Abou-Alfa, Ghassan K, Tjan, Catherine, Covington, Christina, Maynard, Hannah, Allen, Peter J, Askan, Gokce, Leach, Steven D, Iacobuzio-Donahue, Christine A, Robson, Mark E, Offit, Kenneth, Stadler, Zsofia K, O'Reilly, Eileen M

“…Identification of pathogenic germline alterations (PGAs) has important clinical and therapeutic implications in pancreas cancer. We performed comprehensive…”
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Phase II trial of veliparib in patients with previously treated BRCA-mutated pancreas ductal adenocarcinoma by Lowery, Maeve A., Kelsen, David P., Capanu, Marinela, Smith, Sloane C., Lee, Jonathan W., Stadler, Zsofia K., Moore, Malcolm J., Kindler, Hedy L., Golan, Talia, Segal, Amiel, Maynard, Hannah, Hollywood, Ellen, Moynahan, MaryEllen, Salo-Mullen, Erin E., Do, Richard Kinh Gian, Chen, Alice P., Yu, Kenneth H., Tang, Laura H., O'Reilly, Eileen M.

“…BRCA-associated cancers have increased sensitivity to poly(ADP-ribose) polymerase inhibitors (PARPis). This single arm, non-randomised, multicentre phase II…”
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Articles That May Change Your Practice: High-Flow Nasal Cannula for Pediatric Respiratory Distress by MacDonald, Russell D., Lee, Jonathan W.

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