Search Results - "Lee, Joanne C"
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Preferential transduction of parvalbumin-expressing cortical neurons by AAV-mDLX5/6 vectors
Published in Frontiers in neuroscience (12-02-2024)“…A major goal of modern neuroscience is to understand the functions of the varied neuronal types that comprise the mammalian brain. Toward this end, some types…”
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Differential Responses of Retinal Neurons and Glia Revealed via Proteomic Analysis on Primary and Secondary Retinal Ganglion Cell Degeneration
Published in International journal of molecular sciences (28-07-2023)“…To explore the temporal profile of retinal proteomes specific to primary and secondary retinal ganglion cell (RGC) loss. Unilateral partial optic nerve…”
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Use of CRISPRoff and synthetic Notch to modulate and relay endogenous gene expression programs in engineered cells
Published in Frontiers in bioengineering and biotechnology (18-06-2024)“…Uncovering the stimulus-response histories that give rise to cell fates and behaviors is an area of great interest in developmental biology, tissue…”
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Exploring Maleimide-Based Nanoparticle Surface Engineering to Control Cellular Interactions
Published in ACS applied nano materials (27-03-2020)“…Nanoparticle cellular interactions are governed by nanoparticle surface chemistry and the surface display of functional (bio)molecules. To conjugate and…”
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Instructional materials that control cellular activity through synthetic Notch receptors
Published in Biomaterials (01-06-2023)“…The field of regenerative engineering relies primarily on the dual technical platforms of cell selection/conditioning and biomaterial fabrication to support…”
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Templated Pluripotent Stem Cell Differentiation via Substratum-Guided Artificial Signaling
Published in ACS biomaterials science & engineering (14-10-2024)“…The emerging field of synthetic morphogenesis implements synthetic biology tools to investigate the minimal cellular processes sufficient for orchestrating key…”
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Trans-channel fluorescence learning improves high-content screening for Alzheimer’s disease therapeutics
Published in Nature machine intelligence (01-06-2022)“…In microscopy-based drug screens, fluorescent markers carry critical information on how compounds affect different biological processes. However, practical…”
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Preservation of high glycolytic phenotype by establishing new acute lymphoblastic leukemia cell lines at physiologic oxygen concentration
Published in Experimental cell research (15-05-2015)“…Cancer cells typically exhibit increased glycolysis and decreased mitochondrial oxidative phosphorylation, and they continue to exhibit some elevation in…”
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Synthetic regulation of multicellular systems for regenerative engineering
Published in Current opinion in biomedical engineering (01-12-2020)“…Cell therapies represent a vital pillar of the regenerative medicine approach to treating diseases. Unlike small molecules or biologic drugs, cells can…”
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AGED ALZHEIMER’S DISEASE BRAINS EXHIBIT NUMEROUS Aβ BUT ONLY FEW TAU PRIONS
Published in Alzheimer's & dementia (01-07-2018)Get full text
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P4‐233: AGED ALZHEIMER'S DISEASE BRAINS EXHIBIT NUMEROUS Aβ BUT ONLY FEW TAU PRIONS
Published in Alzheimer's & dementia (01-07-2018)Get full text
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