Search Results - "Lee, Jimmy Tsz Hang"

Identification of a protein expression signature distinguishing early from organising diffuse alveolar damage in COVID-19 patients by Ashwin, Helen, Milross, Luke, Wilson, Julie, Majo, Joaquim, Hang Lee, Jimmy Tsz, Calder, Grant, Hunter, Bethany, James, Sally, Lagos, Dimitris, Signoret, Nathalie, Filby, Andrew, Bayraktar, Omer Ali, Fisher, Andrew J, Kaye, Paul M

“…Diffuse alveolar damage (DAD) is the histological expression of acute respiratory distress syndrome and characterises lung pathology due to infection with…”
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Amelioration of non-alcoholic fatty liver disease by targeting adhesion G protein-coupled receptor F1 ( Adgrf1 ) by Wu, Mengyao, Lo, Tak-Ho, Li, Liping, Sun, Jia, Deng, Chujun, Chan, Ka-Ying, Li, Xiang, Yeh, Steve Ting-Yuan, Lee, Jimmy Tsz Hang, Lui, Pauline Po Yee, Xu, Aimin, Wong, Chi-Ming

“…Recent research has shown that the adhesion G protein-coupled receptor F1 ( also known as ) is an oncogene. The evidence is mainly based on high expression of…”
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Correction: Amelioration of non-alcoholic fatty liver disease by targeting adhesion G protein-coupled receptor F1 (Adgrf1) by Wu, Mengyao, Lo, Tak-Ho, Li, Liping, Sun, Jia, Deng, Chujun, Chan, Ka-Ying, Li, Xiang, Yeh, Steve Ting-Yuan, Lee, Jimmy Tsz Hang, Lui, Pauline Po Yee, Xu, Aimin, Wong, Chi-Ming

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A yeast-optimized single-cell transcriptomics platform elucidates how mycophenolic acid and guanine alter global mRNA levels by Urbonaite, Guste, Lee, Jimmy Tsz Hang, Liu, Ping, Parada, Guillermo E., Hemberg, Martin, Acar, Murat

“…Stochastic gene expression leads to inherent variability in expression outcomes even in isogenic single-celled organisms grown in the same environment. The…”
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Author Correction: A yeast-optimized single-cell transcriptomics platform elucidates how mycophenolic acid and guanine alter global mRNA levels by Urbonaite, Guste, Lee, Jimmy Tsz Hang, Liu, Ping, Parada, Guillermo E., Hemberg, Martin, Acar, Murat

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Mining alternative splicing patterns in scRNA-seq data using scASfind by Song, Yuyao, Parada, Guillermo, Lee, Jimmy Tsz Hang, Hemberg, Martin

“…Single-cell RNA-seq (scRNA-seq) is widely used for transcriptome profiling, but most analyses focus on gene-level events, with less attention devoted to…”
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Supervised clustering for single-cell analysis by Lee, Jimmy Tsz Hang, Hemberg, Martin

“…A widely used concept from machine learning is put to use for single-cell analysis…”
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The FGF21-CCL11 Axis Mediates Beiging of White Adipose Tissues by Coupling Sympathetic Nervous System to Type 2 Immunity by Huang, Zhe, Zhong, Ling, Lee, Jimmy Tsz Hang, Zhang, Jialiang, Wu, Donghai, Geng, Leiluo, Wang, Yu, Wong, Chi-Ming, Xu, Aimin

“…Type 2 cytokines are important signals triggering biogenesis of thermogenic beige adipocytes in white adipose tissue (WAT) during cold acclimation. However,…”
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Fast searches of large collections of single-cell data using scfind by Lee, Jimmy Tsz Hang, Patikas, Nikolaos, Kiselev, Vladimir Yu, Hemberg, Martin

“…Single-cell technologies have made it possible to profile millions of cells, but for these resources to be useful they must be easy to query and access. To…”
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Yolk sac cell atlas reveals multiorgan functions during human early development by Goh, Issac, Botting, Rachel A, Rose, Antony, Webb, Simone, Engelbert, Justin, Gitton, Yorick, Stephenson, Emily, Quiroga Londoño, Mariana, Mather, Michael, Mende, Nicole, Imaz-Rosshandler, Ivan, Yang, Lu, Horsfall, Dave, Basurto-Lozada, Daniela, Chipampe, Nana-Jane, Rook, Victoria, Lee, Jimmy Tsz Hang, Ton, Mai-Linh, Keitley, Daniel, Mazin, Pavel, Vijayabaskar, M S, Hannah, Rebecca, Gambardella, Laure, Green, Kile, Ballereau, Stephane, Inoue, Megumi, Tuck, Elizabeth, Lorenzi, Valentina, Kwakwa, Kwasi, Alsinet, Clara, Olabi, Bayanne, Miah, Mohi, Admane, Chloe, Popescu, Dorin-Mirel, Acres, Meghan, Dixon, David, Ness, Thomas, Coulthard, Rowen, Lisgo, Steven, Henderson, Deborah J, Dann, Emma, Suo, Chenqu, Kinston, Sarah J, Park, Jong-Eun, Polanski, Krzysztof, Marioni, John, van Dongen, Stijn, Meyer, Kerstin B, de Bruijn, Marella, Palis, James, Behjati, Sam, Laurenti, Elisa, Wilson, Nicola K, Vento-Tormo, Roser, Chédotal, Alain, Bayraktar, Omer, Roberts, Irene, Jardine, Laura, Göttgens, Berthold, Teichmann, Sarah A, Haniffa, Muzlifah

“…The extraembryonic yolk sac (YS) ensures delivery of nutritional support and oxygen to the developing embryo but remains ill-defined in humans. We therefore…”
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Integrative analysis of transcriptomic and epigenomic data reveals distinct patterns for developmental and housekeeping gene regulation by Abnizova, Irina, Stapel, Carine, Boekhorst, Rene Te, Lee, Jimmy Tsz Hang, Hemberg, Martin

“…Regulation of transcription is central to the emergence of new cell types during development, and it often involves activation of genes via proximal and distal…”
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Demuxafy: improvement in droplet assignment by integrating multiple single-cell demultiplexing and doublet detection methods by Neavin, Drew, Senabouth, Anne, Arora, Himanshi, Lee, Jimmy Tsz Hang, Ripoll-Cladellas, Aida, Franke, Lude, Prabhakar, Shyam, Ye, Chun Jimmie, McCarthy, Davis J, Melé, Marta, Hemberg, Martin, Powell, Joseph E

“…Recent innovations in single-cell RNA-sequencing (scRNA-seq) provide the technology to investigate biological questions at cellular resolution. Pooling cells…”
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Hepatic PRMT1 ameliorates diet-induced hepatic steatosis via induction of PGC1α by Xu, Lu, Huang, Zhe, Lo, Tak-Ho, Lee, Jimmy Tsz Hang, Yang, Ranyao, Yan, Xingqun, Ye, Dewei, Xu, Aimin, Wong, Chi-Ming

“…: Over-nutrition will lead to overexpression of PRMT1 but protein hypomethylation is observed in the liver of obese subjects. The dynamic alteration of the…”
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Adipose-derived lipocalin 14 alleviates hyperglycaemia by suppressing both adipocyte glycerol efflux and hepatic gluconeogenesis in mice by Lee, Jimmy Tsz Hang, Huang, Zhe, Pan, Kewu, Zhang, Herbert Jialiang, Woo, Connie Waihong, Xu, Aimin, Wong, Chi-Ming

“…Aims/hypothesis Growing evidence supports that dysregulation of adipose tissue-derived factors contributes to the pathogenesis of diabetes and its…”
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Cotranscriptional recruitment of yeast TRAMP complex to intronic sequences promotes optimal pre-mRNA splicing by Kong, Ka-Yiu Edwin, Tang, Hei-Man Vincent, Pan, Kewu, Huang, Zhe, Lee, Tsz-Hang Jimmy, Hinnebusch, Alan G, Jin, Dong-Yan, Wong, Chi-Ming

“…Most unwanted RNA transcripts in the nucleus of eukaryotic cells, such as splicing-defective pre-mRNAs and spliced-out introns, are rapidly degraded by the…”
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Coupling and coordination in gene expression processes with pre-mRNA splicing by Pan, Kewu, Lee, Jimmy Tsz Hang, Huang, Zhe, Wong, Chi-Ming

“…A processing is a tightly regulated and highly complex pathway which includes transcription, splicing, editing, transportation, translation and degradation. It…”
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Production of human entorhinal stellate cell-like cells by forward programming shows an important role of Foxp1 in reprogramming by Bergmann, Tobias, Liu, Yong, Skov, Jonathan, Mogus, Leo, Lee, Julie, Pfisterer, Ulrich, Handfield, Louis-Francois, Asenjo-Martinez, Andrea, Lisa-Vargas, Irene, Seemann, Stefan E, Lee, Jimmy Tsz Hang, Patikas, Nikolaos, Kornum, Birgitte Rahbek, Denham, Mark, Hyttel, Poul, Witter, Menno P, Gorodkin, Jan, Pers, Tune H, Hemberg, Martin, Khodosevich, Konstantin, Hall, Vanessa Jane

“…Stellate cells are principal neurons in the entorhinal cortex that contribute to spatial processing. They also play a role in the context of Alzheimer's…”
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Yolk sac cell atlas reveals multiorgan functions during human early development by Goh, Issac, Botting, Rachel, Rose, Antony, Webb, Simone, Engelbert, Justin, Gitton, Yorick, Stephenson, Emily, Quiroga Londoño, Mariana, Mather, Michael, Mende, Nicole, Imaz-Rosshandler, Ivan, Yang, Lu, Horsfall, Dave, Basurto-Lozada, Daniela, Chipampe, Nana-Jane, Rook, Victoria, Lee, Jimmy Tsz Hang, Ton, Mai-Linh, Keitley, Daniel, Mazin, Pavel, Vijayabaskar, M., Hannah, Rebecca, Gambardella, Laure, Green, Kile, Ballereau, Stephane, Inoue, Megumi, Tuck, Elizabeth, Lorenzi, Valentina, Kwakwa, Kwasi, Alsinet, Clara, Olabi, Bayanne, Miah, Mohi, Admane, Chloe, Popescu, Dorin-Mirel, Acres, Meghan, Dixon, David, Ness, Thomas, Coulthard, Rowen, Lisgo, Steven, Henderson, Deborah, Dann, Emma, Suo, Chenqu, Kinston, Sarah, Park, Jong-Eun, Polanski, Krzysztof, Marioni, John, van Dongen, Stijn, Meyer, Kerstin, de Bruijn, Marella, Palis, James, Behjati, Sam, Laurenti, Elisa, Wilson, Nicola, Vento-Tormo, Roser, Chédotal, Alain, Bayraktar, Omer, Roberts, Irene, Jardine, Laura, Göttgens, Berthold, Teichmann, Sarah, Haniffa, Muzlifah

“…The extraembryonic yolk sac (YS) ensures delivery of nutritional support and oxygen to the developing embryo but remains ill-defined in humans. We therefore…”
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Adropin Is a Brain Membrane-bound Protein Regulating Physical Activity via the NB-3/Notch Signaling Pathway in Mice by Wong, Chi-Ming, Wang, Yudong, Lee, Jimmy Tsz Hang, Huang, Zhe, Wu, Donghai, Xu, Aimin, Lam, Karen Siu Ling

“…Adropin is a highly conserved polypeptide that has been suggested to act as an endocrine factor that plays important roles in metabolic regulation, insulin…”
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