Search Results - "Lee, Jia Hui Jane"

Methionine is a metabolic dependency of tumor-initiating cells by Wang, Zhenxun, Yip, Lian Yee, Lee, Jia Hui Jane, Wu, Zhengwei, Chew, Hui Yi, Chong, Pooi Kiat William, Teo, Chin Chye, Ang, Heather Yin-Kuan, Peh, Kai Lay Esther, Yuan, Ju, Ma, Siming, Choo, Li Shi Kimberly, Basri, Nurhidayah, Jiang, Xia, Yu, Qiang, Hillmer, Axel M., Lim, Wan Teck, Lim, Tony Kiat Hon, Takano, Angela, Tan, Eng Huat, Tan, Daniel Shao Weng, Ho, Ying Swan, Lim, Bing, Tam, Wai Leong

“…Understanding cellular metabolism holds immense potential for developing new classes of therapeutics that target metabolic pathways in cancer. Metabolic…”
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PARP4 interacts with hnRNPM to regulate splicing during lung cancer progression by Lee, Yi Fei, Phua, Cheryl Zi Jin, Yuan, Ju, Zhang, Bin, Lee, May Yin, Kannan, Srinivasaraghavan, Chiu, Yui Hei Jasper, Koh, Casslynn Wei Qian, Yap, Choon Kong, Lim, Edwin Kok Hao, Chen, Jianbin, Lim, Yuhua, Lee, Jane Jia Hui, Skanderup, Anders Jacobsen, Wang, Zhenxun, Zhai, Weiwei, Tan, Nguan Soon, Verma, Chandra S, Tay, Yvonne, Tan, Daniel Shao Weng, Tam, Wai Leong

“…The identification of cancer driver genes from sequencing data has been crucial in deepening our understanding of tumor biology and expanding targeted therapy…”
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A Roadmap for Human Liver Differentiation from Pluripotent Stem Cells by Ang, Lay Teng, Tan, Antson Kiat Yee, Autio, Matias I., Goh, Su Hua, Choo, Siew Hua, Lee, Kian Leong, Tan, Jianmin, Pan, Bangfen, Lee, Jane Jia Hui, Lum, Jen Jen, Lim, Christina Ying Yan, Yeo, Isabelle Kai Xin, Wong, Chloe Jin Yee, Liu, Min, Oh, Jueween Ling Li, Chia, Cheryl Pei Lynn, Loh, Chet Hong, Chen, Angela, Chen, Qingfeng, Weissman, Irving L., Loh, Kyle M., Lim, Bing

“…How are closely related lineages, including liver, pancreas, and intestines, diversified from a common endodermal origin? Here, we apply principles learned…”
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Histone variant H3.3 promotes metastasis in alveolar rhabdomyosarcoma by Karthik, Nandini, Lee, Jane Jia Hui, Soon, Joshua Ling Jun, Chiu, Hsin Yao, Loh, Amos Hong Pheng, Ong, Derrick Sek Tong, Tam, Wai Leong, Taneja, Reshma

“…The relatively quiet mutational landscape of rhabdomyosarcoma (RMS) suggests that epigenetic deregulation could be central to oncogenesis and tumour…”
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A Near-Infrared Probe Tracks and Treats Lung Tumor Initiating Cells by Targeting HMOX2 by Kim, Jong-Jin, Lee, Yong-An, Su, Dongdong, Lee, Jungyeol, Park, Sung-Jin, Kim, Beomsue, Jane Lee, Jia Hui, Liu, Xiao, Kim, Seong Soon, Bae, Myung Ae, Lee, Jun-Seok, Hong, Seong Cheol, Wang, Lu, Samanta, Animesh, Kwon, Haw-Young, Choi, So-Young, Kim, Jun-Young, Yu, Young Hyun, Ha, Hyung-Ho, Wang, Zhenxun, Tam, Wai Leong, Lim, Bing, Kang, Nam-Young, Chang, Young-Tae

“…Tumor initiating cells (TIC) are resistant to conventional anticancer therapy and associated with metastasis and relapse in cancer. Although various TIC…”
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Identification of Tumor Initiating Cells with a Small‐Molecule Fluorescent Probe by Using Vimentin as a Biomarker by Lee, Yong‐An, Kim, Jong‐Jin, Lee, Jungyeol, Lee, Jia Hui Jane, Sahu, Srikanta, Kwon, Haw‐Young, Park, Sung‐Jin, Jang, Se‐Young, Lee, Jun‐Seok, Wang, Zhenxun, Tam, Wai Leong, Lim, Bing, Kang, Nam‐Young, Chang, Young‐Tae

“…Tumor initiating cells (TICs) have been implicated in clinical relapse and metastasis of a variety of epithelial cancers, including lung cancer. While efforts…”
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Domain-specific p53 mutants activate EGFR by distinct mechanisms exposing tissue-independent therapeutic vulnerabilities by Ho, Teresa Lai Fong, Lee, May Yin, Goh, Hui Chin, Ng, Germaine Yi Ning, Lee, Jane Jia Hui, Kannan, Srinivasaraghavan, Lim, Yan Ting, Zhao, Tianyun, Lim, Edwin Kok Hao, Phua, Cheryl Zi Jin, Lee, Yi Fei, Lim, Rebecca Yi Xuan, Ng, Perry Jun Hao, Yuan, Ju, Chan, Dedrick Kok Hong, Lieske, Bettina, Chong, Choon Seng, Lee, Kuok Chung, Lum, Jeffrey, Cheong, Wai Kit, Yeoh, Khay Guan, Tan, Ker Kan, Sobota, Radoslaw M., Verma, Chandra S., Lane, David P., Tam, Wai Leong, Venkitaraman, Ashok R.

“…Mis-sense mutations affecting TP53 promote carcinogenesis both by inactivating tumor suppression, and by conferring pro-carcinogenic activities. We report here…”
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Publisher Correction: Methionine is a metabolic dependency of tumor-initiating cells by Wang, Zhenxun, Yip, Lian Yee, Lee, Jia Hui Jane, Wu, Zhengwei, Chew, Hui Yi, Chong, Pooi Kiat William, Teo, Chin Chye, Ang, Heather Yin-Kuan, Peh, Kai Lay Esther, Yuan, Ju, Ma, Siming, Choo, Li Shi Kimberly, Basri, Nurhidayah, Jiang, Xia, Yu, Qiang, Hillmer, Axel M., Lim, Wan Teck, Lim, Tony Kiat Hon, Takano, Angela, Tan, Eng Huat, Tan, Daniel Shao Weng, Ho, Ying Swan, Lim, Bing, Tam, Wai Leong

“…In the version of this article originally published, there is an error in Fig. 5a. Originally, ‘MAT2A’ appeared between ‘Methionine’ and ‘Homocysteine’…”
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Induced-Decay of Glycine Decarboxylase Transcripts as an Anticancer Therapeutic Strategy for Non-Small-Cell Lung Carcinoma by Lin, Jing, Lee, Jia Hui Jane, Paramasivam, Kathirvel, Pathak, Elina, Wang, Zhenxun, Pramono, Zacharias Aloysius Dwi, Lim, Bing, Wee, Keng Boon, Surana, Uttam

“…Self-renewing tumor-initiating cells (TICs) are thought to be responsible for tumor recurrence and chemo-resistance. Glycine decarboxylase, encoded by the GLDC…”
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A chemical-inducible CRISPR–Cas9 system for rapid control of genome editing by Liu, Kaiwen Ivy, Ramli, Muhammad Nadzim Bin, Woo, Cheok Wei Ariel, Wang, Yuanming, Zhao, Tianyun, Zhang, Xiujun, Yim, Guo Rong Daniel, Chong, Bao Yi, Gowher, Ali, Chua, Mervyn Zi Hao, Jung, Jonathan, Lee, Jia Hui Jane, Tan, Meng How

“…A modified version of Cas9 with a fusion of the hormone-binding domain of the estrogen receptor allows reversible control of Cas9 activity with high efficiency…”
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Histone variant H3 .3 promotes metastasis in alveolar rhabdomyosarcoma by Karthik, Nandini, Lee, Jane Jia Hui, Soon, Joshua Ling Jun, Chiu, Hsin Yao, Loh, Amos Hong Pheng, Ong, Derrick Sek Tong, Tam, Wai Leong, Taneja, Reshma

“…Abstract The relatively quiet mutational landscape of rhabdomyosarcoma (RMS) suggests that epigenetic deregulation could be central to oncogenesis and tumour…”
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Theranostics application of tumor-initiating cell probe TiY in non-small cell lung cancer by Lee, Yong-An, Lek, Chee Chong Jonathan, Rong, Gao, Wu, Zhengwei, Shathishwaran, S, Lee, Jia Hui Jane, Tam, Wai Leong, Wuestefeld, Torsten, Park, Sung-Jin, Jung, Sangyong, Kim, Beomsue, Kang, Nam-Young, Chang, Young-Tae

“…Tumor-initiating cells (TIC) often elude conventional cancer treatment, which results in metastasis and cancer relapse. Recently, studies have begun to focus…”
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Identification of Tumor Initiating Cells with a Small‐Molecule Fluorescent Probe by Using Vimentin as a Biomarker by Lee, Yong‐An, Kim, Jong‐Jin, Lee, Jungyeol, Lee, Jia Hui Jane, Sahu, Srikanta, Kwon, Haw‐Young, Park, Sung‐Jin, Jang, Se‐Young, Lee, Jun‐Seok, Wang, Zhenxun, Tam, Wai Leong, Lim, Bing, Kang, Nam‐Young, Chang, Young‐Tae

“…Tumor initiating cells (TICs) have been implicated in clinical relapse and metastasis of a variety of epithelial cancers, including lung cancer. While efforts…”
Get full text