Search Results - "Lee, Jennifer S"
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Triglyceride and HDL-C Dyslipidemia and Risks of Coronary Heart Disease and Ischemic Stroke by Glycemic Dysregulation Status: The Strong Heart Study
Published in Diabetes care (01-04-2017)“…High triglyceride (TG) levels and low HDL cholesterol (HDL-C) levels are risk factors for cardiovascular disease. It is unclear whether this relationship…”
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2
Metabolic Obesity Phenotypes and Risk of Breast Cancer in Postmenopausal Women
Published in Cancer epidemiology, biomarkers & prevention (01-12-2017)“…Obesity and the metabolic syndrome (MetS) have both been linked to increased risk of postmenopausal breast cancer; however, their relative contributions are…”
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3
Persistent Subclinical Hypothyroidism and Cardiovascular Risk in the Elderly: The Cardiovascular Health Study
Published in The journal of clinical endocrinology and metabolism (01-02-2013)“…Context: Use of a single set of thyroid function tests to define subclinical hypothyroidism may lead to misclassification over time and could influence…”
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Bone mineral density loss in relation to the final menstrual period in a multiethnic cohort: Results from the Study of Women's Health Across the Nation (SWAN)
Published in Journal of bone and mineral research (01-01-2012)“…The objective of this study was to describe the time of onset and offset of bone mineral density (BMD) loss relative to the date of the final menstrual period…”
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5
Predicting clinical outcomes of SARS-CoV-2 infection during the Omicron wave using machine learning
Published in PloS one (25-04-2024)“…The Omicron SARS-CoV-2 variant continues to strain healthcare systems. Developing tools that facilitate the identification of patients at highest risk of…”
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Herpesviral ICP0 Protein Promotes Two Waves of Heterochromatin Removal on an Early Viral Promoter during Lytic Infection
Published in mBio (12-01-2016)“…Herpesviruses must contend with host cell epigenetic silencing responses acting on their genomes upon entry into the host cell nucleus. In this study, we…”
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Development of intravenously administered synthetic RNA virus immunotherapy for the treatment of cancer
Published in Nature communications (07-10-2022)“…The therapeutic effectiveness of oncolytic viruses (OVs) delivered intravenously is limited by the development of neutralizing antibody responses against the…”
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Long-term HIV care outcomes under universal HIV treatment guidelines: A retrospective cohort study in 25 countries
Published in PLoS medicine (18-03-2024)“…While national adoption of universal HIV treatment guidelines has led to improved, timely uptake of antiretroviral therapy (ART), longer-term care outcomes are…”
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Standardization of Steroid Hormone Assays: Why, How, and When?
Published in Cancer epidemiology, biomarkers & prevention (01-09-2007)“…Lack of standardization of high-quality steroid hormone assays is a major deficiency in epidemiologic studies. In postmenopausal women, reported levels of…”
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10
Inhibition of LSD1 reduces herpesvirus infection, shedding, and recurrence by promoting epigenetic suppression of viral genomes
Published in Science translational medicine (03-12-2014)“…Herpesviruses are highly prevalent and maintain lifelong latent reservoirs, thus posing challenges to the control of herpetic disease despite the availability…”
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Clues to mechanisms of herpesviral latent infection and potential cures
Published in Proceedings of the National Academy of Sciences - PNAS (29-09-2015)Get full text
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CCCTC-Binding Factor Acts as a Heterochromatin Barrier on Herpes Simplex Viral Latent Chromatin and Contributes to Poised Latent Infection
Published in mBio (06-02-2018)“…Herpes simplex virus 1 (HSV-1) establishes latent infection in neurons via a variety of epigenetic mechanisms that silence its genome. The cellular…”
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Acupuncture for Pain and Dysfunction After Neck Dissection: Results of a Randomized Controlled Trial
Published in Journal of clinical oncology (20-05-2010)“…To determine whether acupuncture reduces pain and dysfunction in patients with cancer with a history of neck dissection. The secondary objective is to…”
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Triglyceride Levels and Fracture Risk in Midlife Women: Study of Women's Health Across the Nation (SWAN)
Published in The journal of clinical endocrinology and metabolism (01-09-2016)“…Context: Unfavorable lipid levels contribute to cardiovascular disease and may also harm bone health. Objective: Our objective was to investigate relationships…”
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A statistical quality assessment method for longitudinal observations in electronic health record data with an application to the VA million veteran program
Published in BMC medical informatics and decision making (20-10-2021)“…Abstract Background To describe an automated method for assessment of the plausibility of continuous variables collected in the electronic health record…”
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Anabolic and Antiresorptive Osteoporosis Treatment: Trends, Costs, and Sequence in a Commercially Insured Population, 2003–2021
Published in JBMR plus (01-10-2023)“…ABSTRACT New anabolic medications (abaloparatide and romosozumab) were recently approved for osteoporosis, and data suggest that prescribing antiresorptive…”
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Incidence of Second Malignancy in Patients with Papillary Thyroid Cancer from Surveillance, Epidemiology, and End Results 13 Dataset
Published in Journal of thyroid research (01-01-2018)“…Increased risk of second primary malignancy (SPM) in papillary thyroid cancer (PTC) has been reported. Here, we present the most updated incidence rates of…”
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Comparison of Methods to Measure Low Serum Estradiol Levels in Postmenopausal Women
Published in The journal of clinical endocrinology and metabolism (01-10-2006)“…Context: Accurate measurement of low serum estradiol (E2 < 30 pg/ml or < 110 pmol/liter) is needed to study relationships between endogenous E2 and risks of…”
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A Herpesviral Lytic Protein Regulates the Structure of Latent Viral Chromatin
Published in mBio (17-05-2016)“…Latent infections by viruses usually involve minimizing viral protein expression so that the host immune system cannot recognize the infected cell through the…”
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Environmental tobacco smoke and risk of late-diagnosis incident fibroids in the Study of Women's Health across the Nation (SWAN)
Published in Fertility and sterility (01-10-2016)“…Objective To assess the longitudinal relationship of environmental tobacco smoke (ETS) exposure during midlife, and its interaction with active smoking, with…”
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