Search Results - "Lee, Janus"
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Association of plasma ceramide with decline in kidney function in patients with type 2 diabetes
Published in Journal of lipid research (01-06-2024)“…Circulating ceramide levels are dysregulated in kidney disease. However, their associations with rapid decline in kidney function (RDKF) and end-stage kidney…”
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Acute kidney injury predicts the risk of adverse cardio renal events and all cause death in southeast Asian people with type 2 diabetes
Published in Scientific reports (07-11-2024)“…Patients with diabetes are susceptible to acute kidney injury (AKI) as compared to counterparts without diabetes. However, data on the long-term clinical…”
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Incident heart failure and the subsequent risk of progression to end stage kidney disease in individuals with type 2 diabetes
Published in Cardiovascular diabetology (15-06-2024)“…Diabetic kidney disease is an established risk factor for heart failure. However, the impact of incident heart failure on the subsequent risk of renal failure…”
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Aortic pulse wave velocity, central pulse pressure, augmentation index and chronic kidney disease progression in individuals with type 2 diabetes: a 3- year prospective study
Published in BMC nephrology (20-08-2020)“…Pulse wave velocity (PWV), central pulse pressure and augmentation index are arterial stiffness- related hemodynamic parameters but their associations with…”
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Plasma ceramides predict all-cause and cause-specific mortality in individuals with type 2 diabetes
Published in The journal of clinical endocrinology and metabolism (08-06-2024)“…The CERT1 (Cardiovascular Event Risk Test) score derived from plasma ceramides has been applied clinically for cardiovascular risk assessment. To study whether…”
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Plasma Tryptophan-Kynurenine Pathway Metabolites and Risk for Progression to End-Stage Kidney Disease in Patients With Type 2 Diabetes
Published in Diabetes care (01-12-2023)“…We sought to study the associations between plasma metabolites in the tryptophan-kynurenine pathway and the risk of progression to end-stage kidney disease…”
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Risk of Incident Heart Failure in Individuals With Early-Onset Type 2 Diabetes
Published in The journal of clinical endocrinology and metabolism (01-01-2022)“…Early-onset diabetes has been associated with unfavorable cardiovascular risk but data on heart failure (HF) in this subpopulation are scarce. We aimed to…”
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Clinical variable-based cluster analysis identifies novel subgroups with a distinct genetic signature, lipidomic pattern and cardio-renal risks in Asian patients with recent-onset type 2 diabetes
Published in Diabetologia (01-12-2022)“…Aims/hypothesis We sought to subtype South East Asian patients with type 2 diabetes by de novo cluster analysis on clinical variables, and to determine whether…”
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Urine Leucine-Rich α-2 Glycoprotein 1 (LRG1) Predicts the Risk of Progression to End-Stage Kidney Disease in Patients With Type 2 Diabetes
Published in Diabetes care (01-02-2023)“…Leucine-rich α-2 glycoprotein 1 (LRG1) was recently identified as an amplifier of transforming growth factor-β (TGF-β)-induced kidney fibrosis in animal…”
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Urine tricarboxylic acid cycle metabolites and risk of end stage kidney disease in patients with type 2 diabetes
Published in The journal of clinical endocrinology and metabolism (28-03-2024)“…Metabolites in tricarboxylic acid (TCA) pathway have pleiotropic functions. To study the association between urine TCA cycle metabolites and the risk for…”
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Association of major candidate protein biomarkers and long-term diabetic kidney disease progression among Asians with young-onset type 2 diabetes mellitus
Published in Diabetes research and clinical practice (01-10-2024)“…We aim to determine the association of seven major candidate protein biomarkers and diabetic kidney disease (DKD) progression among Asians with young-onset…”
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Association of Plasma Leucine-Rich Alpha-2 Glycoprotein 1
Published in Clinical chemistry (Baltimore, Md.) (01-12-2021)Get full text
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Association of Plasma Leucine-Rich Alpha-2 Glycoprotein 1 (LRG1) with All-Cause and Cause-Specific Mortality in Individuals with Type 2 Diabetes
Published in Clinical chemistry (Baltimore, Md.) (01-12-2021)“…Abstract Background Leucine-rich alpha-2 glycoprotein 1 (LRG1) is a circulating protein in the transforming growth factor-beta superfamily. We sought to study…”
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Nutrient residence times in relation to the trophic condition of lakes
Published 01-01-1989“…This thesis is concerned with defining systematic relationships between nutrient flow rates in aquatic ecosystems and their overall biological productivity…”
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Dissertation