Search Results - "Lee, Jaeok"

Dual Inhibition of P-gp and BCRP Improves Oral Topotecan Bioavailability in Rodents by Lee, Jaeok, Kang, Jiyeon, Kwon, Na-Yun, Sivaraman, Aneesh, Naik, Ravi, Jin, So-Young, Oh, A Reum, Shin, Jae-Ho, Na, Younghwa, Lee, Kyeong, Lee, Hwa-Jeong

“…P-glycoprotein (P-gp) inhibition has been studied to overcome multidrug resistance in cancer chemotherapy but failed in clinical trials due to low/toxic…”
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Pharmacokinetic Study of NADPH Oxidase Inhibitor Ewha-18278, a Pyrazole Derivative by Lee, Seul Gee, Lee, Jaeok, Kim, Kyung Min, Lee, Kee-In, Bae, Yun Soo, Lee, Hwa Jeong

“…In a previous study, the specific NOX1/2/4 inhibitor Ewha-18278 was confirmed as a possible treatment for osteoporosis both in vitro and in vivo. Here, we…”
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Quantification of Teicoplanin Using the HPLC-UV Method for Clinical Applications in Critically Ill Patients in Korea by Lee, Jaeok, Chung, Eun-Kyoung, Kang, Sung-Wook, Lee, Hwa-Jeong, Rhie, Sandy-Jeong

“…A high-performance liquid chromatography-ultraviolet detector (HPLC-UV) method has been used to quantify teicoplanin concentrations in human plasma. However,…”
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Epigenetics: An emerging player in gastric cancer by Kang, Changwon, Song, Ji-Joon, Lee, Jaeok, Kim, Mi Young

“…Cancers,like other diseases,arise from gene mutations and/or altered gene expression,which eventually cause dysregulation of numerous proteins and noncoding…”
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Drug-Like Small Molecule HSP27 Functional Inhibitor Sensitizes Lung Cancer Cells to Gefitinib or Cisplatin by Inducing Altered Cross-Linked Hsp27 Dimers by Yoo, Hawon, Choi, Seul-Ki, Lee, Jaeok, Park, So Hyeon, Park, You Na, Hwang, Soo-Yeon, Shin, Jae-Ho, Na, Younghwa, Kwon, Youngjoo, Lee, Hwa Jeong, Lee, Yun-Sil

“…Relationships between heat shock protein 27 (HSP27) and cancer aggressiveness, metastasis, drug resistance, and poor patient outcomes in various cancer types…”
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Pharmacokinetic Alteration of Paclitaxel by Ferulic Acid Derivative by Lee, Jaeok, Chae, Song Wha, Ma, LianJi, Lim, So Yeon, Alnajjar, Sarah, Park Choo, Hea-Young, Lee, Hwa Jeong, Rhie, Sandy Jeong

“…P-glycoprotein (P-gp) is known to be involved in multidrug resistance (MDR) and modulation of pharmacokinetic (PK) profiles of substrate drugs. Here, we…”
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Effects of Piperazine Derivative on Paclitaxel Pharmacokinetics by Lee, Jaeok, Chae, Song Wha, Oh, A Reum, Yoo, Ji Hye, Park Choo, Hea-Young, Rhie, Sandy Jeong, Lee, Hwa Jeong

“…Paclitaxel (PTX) is an anticancer agent that is used to treat many cancers but it has a very low oral bioavailability due, at least in part, to the drug efflux…”
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Tetramidocavitand: strong anion receptor by well-organized four –(C O)N–H⋯X − interactions by Jung, Nak Shin, Lee, Jaeok, Choi, Sang Beom, Kim, Jaheon, Paek, Kyungsoo

“…Resorcin[4]arene-based tetramidocavitands containing four secondary amide groups on their upper rim showed strong RSO 3 - (R = methyl or ethyl) binding…”
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BEAR: A Novel Virtual Screening Method Based on Large-Scale Bioactivity Data by Kwon, Yeajee, Park, Sera, Lee, Jaeok, Kang, Jiyeon, Lee, Hwa Jeong, Kim, Wankyu

“…Data-driven drug discovery exploits a comprehensive set of big data to provide an efficient path for the development of new drugs. Currently, publicly…”
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COVID-19 drugs: potential interaction with ATP-binding cassette transporters P-glycoprotein and breast cancer resistance protein by Lee, Jaeok, Kim, Jihye, Kang, Jiyeon, Lee, Hwa Jeong

“…Background The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2, has resulted in acute respiratory…”
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Population pharmacokinetics and model-based dosing optimization of teicoplanin in elderly critically ill patients with pneumonia by Kang, Sung Wook, Jo, Hyeong Geun, Kim, Donghyun, Jeong, Kyeoul, Lee, Jaeok, Lee, Hwa Jeong, Yang, Seungwon, Park, Sohyun, Rhie, Sandy Jeong, Chung, Eun Kyoung

“…To evaluate the population pharmacokinetics and pharmacodynamics of teicoplanin in elderly critically ill patients with pneumonia for optimal dosages. Fifteen…”
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Intestinal P‐glycoprotein inhibitors, benzoxanthone analogues by Chae, Song Wha, Lee, Jaeok, Park, Jung Hyun, Kwon, Youngjoo, Na, Younghwa, Lee, Hwa Jeong

“…Objectives The inhibitors of P‐glycoprotein (P‐gp) which limits an access of exogenous compounds in the luminal membrane of the intestine have been studied to…”
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14K prolactin derived 14-mer antiangiogenic peptide targets bradykinin-/nitric oxide-cGMP-dependent angiogenesis by Lee, Jaeok, Kumar, Pavitra, Natarajan, Suganya, Park, So Hyeon, Majumder, Syamantak, Sundaresan, Lakshmikirupa, Muralidhar, Kambadur, Choi, Jong-Soon, Lee, Hwa Jeong, Chatterjee, Suvro

“…Over the past few decades, VEGF-targeted antiangiogenic therapy for cancers has gained increasing attention. Nevertheless, there are still several limitations…”
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On the Nature of Propagating Intensity Disturbances in Polar Plumes during the 2017 Total Solar Eclipse by Cho, Kyung-Suk, Cho, Il-Hyun, Madjarska, Maria S., Nakariakov, Valery M., Yang, Heesu, Choi, Seonghwan, Lim, Eun-Kyung, Lee, Kyung-Sun, Seough, Jung-Jun, Lee, Jaeok, Kim, Yeon-Han

“…Abstract The propagating intensity disturbances (PIDs) in plumes are still poorly understood, and their identity (magnetoacoustic waves or flows) remains an…”
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Inhibitory activity of the peptides derived from buffalo prolactin on angiogenesis by Lee, Jaeok, Majumder, Syamantak, Chatterjee, Suvro, Muralidhar, Kambadur

“…The peptide fragments obtained by cathepsin digestion of purified buffalo prolactin (buPRL) monomer have been characterized using SDS-PAGE and FPLC with regard…”
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On the Nature of Propagating Intensity Disturbances in Polar Plumes during the 2017 Total Solar Eclipse by Cho, Kyung-Suk, Cho, Il-Hyun, Madjarska, Maria S, Nakariakov, Valery M, Yang, Heesu, Choi, Seonghwan, Lim, Eun-Kyung, Lee, Kyung-Sun, Seough, Jung-Jun, Lee, Jaeok, Kim, Yeon-Han

“…The propagating intensity disturbances (PIDs) in plumes are still poorly understood and their identity (magnetoacoustic waves or flows) remains an open…”
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Features for a B-ISDN telemedicine system and its application by Choi, J, Kim, Y, Lee, S, Lee, J, Woo, J, Seo, J, Yoo, T, Cho, H

“…Telemedicine technology is emerging as a new way of medical practice. It will provide more cooperative activity between departments and more comfortable access…”
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A Telemedicine System Using B-ISDN by Choi, Jinwook, Kim, Younghan, Lee, Sanggoo, Lee, Jaeok, Oh, Byunghee, Cho, Hanik

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