Search Results - "Lee, Jacqueline E."
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Math3 and NeuroD regulate amacrine cell fate specification in the retina
Published in Development (Cambridge) (15-02-2002)“…The basic helix-loop-helix genes Math3 and NeuroD are expressed by differentiating amacrine cells, retinal interneurons. Previous studies have demonstrated…”
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Requirement of Multiple Basic Helix-Loop-Helix Genes for Retinal Neuronal Subtype Specification
Published in The Journal of biological chemistry (02-07-2004)“…Retinal precursor cells give rise to six types of neurons and one type of glial cell during development, and this process is controlled by multiple basic…”
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Improving the accuracy of intraoperative perforator location in DIEP flaps
Published in Journal of plastic, reconstructive & aesthetic surgery (01-02-2014)Get full text
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ESCRT-independent budding of HIV-1 gag virus-like particles from Saccharomyces cerevisiae spheroplasts
Published in PloS one (21-12-2012)“…Heterologous expression of HIV-1 Gag in a variety of host cells results in its packaging into virus-like particles (VLPs) that are subsequently released into…”
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NeuroD: the predicted and the surprising
Published in Molecules and cells (31-12-2004)“…NeuroD (otherwise known as BETA2) is a basic helix-loop-helix (bHLH) transcription factor that is capable of converting embryonic epidermal cells into fully…”
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Stimulation of NeuroD Activity by Huntingtin and Huntingtin-Associated Proteins HAP1 and MLK2
Published in Proceedings of the National Academy of Sciences - PNAS (05-08-2003)“…NeuroD (ND) is a basic helix-loop-helix transcription factor important for neuronal development and survival. By using a yeast two-hybrid screen, we identified…”
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Pancreatic β Cells Require NeuroD to Achieve and Maintain Functional Maturity
Published in Cell metabolism (07-04-2010)“…NeuroD, a transactivator of the insulin gene, is critical for development of the endocrine pancreas, and NeuroD mutations cause MODY6 in humans. To investigate…”
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Defects in the cerebella of conditional Neurod1 null mice correlate with effective Tg(Atoh1-cre) recombination and granule cell requirements for Neurod1 for differentiation
Published in Cell and tissue research (01-09-2009)“…Neurod1 is a crucial basic helix-loop-helix gene for most cerebellar granule cells and mediates the differentiation of these cells downstream of Atoh1-mediated…”
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Intraoperative Tissue Perfusion Measurement by Laser Speckle Imaging: A Potential Aid for Reducing Postoperative Complications in Free Flap Breast Reconstruction
Published in Plastic and reconstructive surgery (1963) (01-02-2019)“…Adequate tissue perfusion is essential to minimize postoperative complications following microsurgery. Intraoperative knowledge of tissue perfusion could aid…”
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Membrane Protein Targeting to the MVB/Lysosome
Published in Chemical reviews (01-04-2009)“…The multivesicular body sorting reaction in the endocytic pathway is discussed. The role of ubiquitin in sorting membrane proteins for degradation is explored…”
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Basic helix-loop-helix genes in neural development
Published in Current opinion in neurobiology (01-02-1997)“…Several major advances in the understanding of the regulation of vertebrate neurogenesis by members of the basic helix-loop-helix (bHLH) protein family have…”
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Genetic identification of a novel NeuroD1 function in the early differentiation of islet α, PP and ε cells
Published in Developmental biology (15-12-2007)“…Nkx2.2 and NeuroD1 are vital for proper differentiation of pancreatic islet cell types. Nkx2.2-null mice fail to form β cells, have reduced numbers of α and PP…”
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Expression of neurogenin3 reveals an islet cell precursor population in the pancreas
Published in Development (Cambridge) (15-08-2000)“…Differentiation of early gut endoderm cells into the endocrine cells forming the pancreatic islets of Langerhans depends on a cascade of gene activation events…”
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The HECT Domain of the Ubiquitin Ligase Rsp5 Contributes to Substrate Recognition
Published in The Journal of biological chemistry (13-11-2009)“…Ubiquitin modification of endosomal membrane proteins is a signal for active inclusion into the Multivesicular Body (MVB) pathway, resulting in lysosomal…”
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NeuroD regulates multiple functions in the developing neural retina in rodent
Published in Development (Cambridge) (01-01-1999)“…The expression and function of the basic helix-loop-helix (bHLH) transcription factor NeuroD were studied in the developing neural retina in rodent. neuroD was…”
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NeuroD-null mice are deaf due to a severe loss of the inner ear sensory neurons during development
Published in Development (Cambridge) (01-02-2001)“…A key factor in the genetically programmed development of the nervous system is the death of massive numbers of neurons. Therefore, genetic mechanisms…”
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Conversion of Xenopus Ectoderm into Neurons by NeuroD, a Basic Helix-Loop- Helix Protein
Published in Science (American Association for the Advancement of Science) (12-05-1995)“…Basic helix-loop-helix (bHLH) proteins are instrumental in determining cell type during development. A bHLH protein, termed NeuroD, for neurogenic…”
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Recovery of neurological functions in non-human primate model of Parkinson's disease by transplantation of encapsulated neonatal porcine choroid plexus cells
Published in Journal of Parkinson's disease (01-01-2013)“…Parkinson's disease (PD) is a neurodegenerative disease that is primarily characterized by degeneration of dopaminergic (DA) neurons in the substantia nigra…”
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