Search Results - "Lee, Im Soon"
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Therapeutic Potential of Volatile Terpenes and Terpenoids from Forests for Inflammatory Diseases
Published in International journal of molecular sciences (22-03-2020)“…Forest trees are a major source of biogenic volatile organic compounds (BVOCs). Terpenes and terpenoids are known as the main BVOCs of forest aerosols. These…”
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Neuroprotective Effects of Limonene (+) against Aβ42-Induced Neurotoxicity in a Drosophila Model of Alzheimer’s Disease
Published in Biological & pharmaceutical bulletin (01-03-2020)“…Forest bathing is suggested to have beneficial effects on various aspects of human health. Terpenes, isoprene based-phytochemicals emitted from trees, are…”
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NSD Overexpression in the Fat Body Increases Antimicrobial Peptide Production by the Immune Deficiency Pathway in Drosophila
Published in International journal of molecular sciences (08-05-2023)“…Nuclear receptor-binding SET domain-containing protein 1 (NSD1) inactivation in tumor cells contributes to an immune-cold phenotype, indicating its potential…”
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Drosophila Glia: Models for Human Neurodevelopmental and Neurodegenerative Disorders
Published in International journal of molecular sciences (09-07-2020)“…Glial cells are key players in the proper formation and maintenance of the nervous system, thus contributing to neuronal health and disease in humans. However,…”
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Terpenes from Forests and Human Health
Published in Toxicological research (Seoul) (01-04-2017)“…Forest bathing has beneficial effects on human health via showering of forest aerosols as well as physical relaxation. Terpenes that consist of multiple…”
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The function of Scox in glial cells is essential for locomotive ability in Drosophila
Published in Scientific reports (27-10-2021)“…Synthesis of cytochrome c oxidase ( Scox ) is a Drosophila homolog of human SCO2 encoding a metallochaperone that transports copper to cytochrome c, and is an…”
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Overexpression of H3K36 methyltransferase NSD in glial cells affects brain development in Drosophila
Published in Glia (01-12-2020)“…NSD1 is a histone methyltransferase that methylates the lysine 36 at histone H3. NSD duplication is associated with short stature, microcephaly, intellectual…”
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Negative regulation and developmental competence in Aspergillus
Published in Scientific reports (01-07-2016)“…Asexual development (conidiation) in the filamentous fungus Aspergillus nidulans is governed by orchestrated gene expression. The three key negative regulators…”
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Cell-Penetrating, Dimeric α-Helical Peptides: Nanomolar Inhibitors of HIV-1 Transcription
Published in Angewandte Chemie International Edition (15-09-2014)“…We constructed dimeric α‐helical peptide bundles based on leucine (L) and lysine (K) residues for both efficient cell penetration and inhibition of the Tat–TAR…”
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Drosophila DJ-1 decreases neural sensitivity to stress by negatively regulating Daxx-like protein through dFOXO
Published in PLoS genetics (01-04-2013)“…DJ-1, a Parkinson's disease (PD)-associated gene, has been shown to protect against oxidative stress in Drosophila. However, the molecular mechanism underlying…”
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Histone Lysine Methylation and Neurodevelopmental Disorders
Published in International journal of molecular sciences (30-06-2017)“…Methylation of several lysine residues of histones is a crucial mechanism for relatively long-term regulation of genomic activity. Recent molecular biological…”
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Submerged leaves of live indoor foliage plants adsorb H1N1 influenza virus from suspension
Published in Plant signaling & behavior (31-12-2023)“…Control of hazardous indoor particles using plants has attracted interest due to the increasing worldwide air pollution and spread of pandemic-causing viruses…”
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Detection of Foot‐and‐Mouth Disease Virus Using a Polydiacetylene Immunosensor on Solid‐Liquid Phase
Published in Macromolecular materials and engineering (01-06-2018)“…The rapid detection of foot‐and‐mouth disease virus (FMDV) is vital for the prevention of foot‐and‐mouth disease outbreaks. In this study, a polyvinylidene…”
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Evaluation of Antibacterial and Antiviral Compounds from Commiphora myrrha (T.Nees) Engl. Resin and Their Promising Application with Biochar
Published in Applied sciences (01-09-2023)“…Commiphora myrrha (T.Nees) Engl. resin extracts were prepared via immersion in extraction solvents (hot water, DMSO, hexane, ethanol, and methanol) which have…”
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In Vivo Screening of Traditional Medicinal Plants for Neuroprotective Activity against Aβ42 Cytotoxicity by Using Drosophila Models of Alzheimer’s Disease
Published in Biological & pharmaceutical bulletin (2015)“…Alzheimer’s disease (AD) is the most common neurodegenerative disorder, characterized by progressive neuronal loss with amyloid β-peptide (Aβ) plaques. Despite…”
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High-Throughput Profiling of Peptide–RNA Interactions Using Peptide Microarrays
Published in Journal of the American Chemical Society (21-11-2012)“…A rapid and quantitative method to evaluate binding properties of hairpin RNAs to peptides using peptide microarrays has been developed. The microarray…”
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The calcineurin inhibitor Sarah (Nebula) exacerbates Aβ42 phenotypes in a Drosophila model of Alzheimer's disease
Published in Disease models & mechanisms (01-03-2016)“…Expression of the Down syndrome critical region 1 (DSCR1) protein, an inhibitor of the Ca(2+)-dependent phosphatase calcineurin, is elevated in the brains of…”
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Label-Free Colorimetric Detection of Influenza Antigen Based on an Antibody-Polydiacetylene Conjugate and Its Coated Polyvinylidene Difluoride Membrane
Published in Polymers (30-03-2017)“…This study presents an antibody-conjugated polydiacetylene (PDA) and its coated polyvinylidene difluoride (PVDF) membrane. The M149 antibody was hybridized to…”
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Polymorphic metabolism by functional alterations of human cytochrome P450 enzymes
Published in Archives of pharmacal research (01-11-2011)“…The study of cytochrome P450 pharmacogenomics is of particular interest because of its promise in the development of rational means to optimize drug therapy…”
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Suppressive Effects of SuHeXiang Wan on Amyloid-β42-Induced Extracellular Signal-Regulated Kinase Hyperactivation and Glial Cell Proliferation in a Transgenic Drosophila Model of Alzheimer's Disease
Published in Biological & pharmaceutical bulletin (2013)“…SuHeXiang Wan (SHXW), a Chinese traditional medicine, has been used to treat infantile convulsions, seizures and strokes. Previously, we reported that modified…”
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