Search Results - "Lee, HyunKyoung"
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Fucoidan from seaweed Fucus vesiculosus inhibits migration and invasion of human lung cancer cell via PI3K-Akt-mTOR pathways
Published in PloS one (30-11-2012)“…Recently there has been an increased interest in the pharmacologically active natural products associated with remedies of various kinds of diseases, including…”
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Evaluation of anti-oxidant and anti-cancer properties of Dendropanax morbifera Léveille
Published in Food chemistry (01-12-2013)“…•Debarked stems extract of Dendropanax morbifera Léveille showed the highest antioxidant activity.•The methanolic extracts of leaves and debarked stems…”
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3
Axon-dependent expression of YAP/TAZ mediates Schwann cell remyelination but not proliferation after nerve injury
Published in eLife (21-05-2020)“…Previously we showed that YAP/TAZ promote not only proliferation but also differentiation of immature Schwann cells (SCs), thereby forming and maintaining the…”
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4
Toll-like receptors: sensor molecules for detecting damage to the nervous system
Published in Current protein & peptide science (01-02-2013)“…Toll-like receptors (TLRs) are type I transmembrane signaling molecules that are expressed in cells of the innate immune system. In these cells, TLRs function…”
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5
Dendritic spine and synapse pathology in chromatin modifier-associated autism spectrum disorders and intellectual disability
Published in Frontiers in molecular neuroscience (19-01-2023)“…Formation of dendritic spine and synapse is an essential final step of brain wiring to establish functional communication in the developing brain. Recent…”
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6
Setaria digitata was the main cause of equine neurological ataxia in Korea: 50 cases (2015–2016)
Published in Journal of Veterinary Medical Science (2021)“…This study was performed to examine and clarify the cause of hindlimb ataxia and neuropathy seen in the South Korean horse population. Fifty horses diagnosed…”
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Differential roles of ARID1B in excitatory and inhibitory neural progenitors in the developing cortex
Published in Scientific reports (16-02-2021)“…Genetic evidence indicates that haploinsufficiency of ARID1B causes intellectual disability (ID) and autism spectrum disorder (ASD), but the neural function of…”
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Highly Pathogenic Avian Influenza A(H5N6) in Domestic Cats, South Korea
Published in Emerging infectious diseases (01-12-2018)“…In December 2016, highly pathogenic avian influenza (HPAI) infection with systemic pathologic lesions was found in cats in South Korea. Genetic analyses…”
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TLR2-induced astrocyte MMP9 activation compromises the blood brain barrier and exacerbates intracerebral hemorrhage in animal models
Published in Molecular brain (10-04-2015)“…The innate immune response plays an important role in the pathogenesis of intracerebral hemorrhage (ICH). Recent studies have shown that Toll-like receptor 2…”
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10
Proteomic Analysis of Novel Components of Nemopilema nomurai Jellyfish Venom: Deciphering the Mode of Action
Published in Toxins (08-03-2019)“…Nowadays, proliferation of jellyfish has become a severe matter in many coastal areas around the world. Jellyfish is one of the most perilous organisms and…”
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Formaldehyde-Induced Aggravation of Pruritus and Dermatitis Is Associated with the Elevated Expression of Th1 Cytokines in a Rat Model of Atopic Dermatitis
Published in PloS one (22-12-2016)“…Atopic dermatitis is a complex disease of heterogeneous pathogenesis, in particular, genetic predisposition, environmental triggers, and their interactions…”
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Therapeutic Effect of Rumex japonicus Houtt. on DNCB-Induced Atopic Dermatitis-Like Skin Lesions in Balb/c Mice and Human Keratinocyte HaCaT Cells
Published in Nutrients (07-03-2019)“…Houtt. (RJ) is traditionally used in folk medicines to treat patients suffering from skin disease in Korea and other parts of East Asia. However, the…”
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Association of TRPV1 and TLR4 through the TIR domain potentiates TRPV1 activity by blocking activation-induced desensitization
Published in Molecular pain (01-01-2018)“…Background We have previously reported that histamine-induced pruritus was attenuated in toll-like receptor 4 (TLR4) knockout mice due to decreased transient…”
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Case report: Pathology, antimicrobial resistance, and molecular characterization of bovine abortion cases caused by Nocardia farcinica in Korean native cattle
Published in Frontiers in veterinary science (21-08-2024)“…is an opportunistic bacterium that causes bovine mastitis and pulmonary, cutaneous, and central nervous system infections in humans. Bovine abortion caused by…”
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Proteomic Investigation to Identify Anticancer Targets of Nemopilema nomurai Jellyfish Venom in Human Hepatocarcinoma HepG2 Cells
Published in Toxins (10-05-2018)“…is a giant jellyfish that blooms in East Asian seas. Recently, venom (NnV) was characterized from a toxicological and pharmacological point of view. A mild…”
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Pathogenicity and Pathological Characteristics of African Swine Fever Virus Strains from Pig Farms in South Korea from 2022 to January 2023
Published in Pathogens (Basel) (01-09-2023)“…Since the first African swine fever (ASF) outbreak occurred at a pig farm in South Korea in September 2019, as of 31 January 2023, 31 ASF cases have occurred…”
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Enzymatic analysis of Hemiscorpius lepturus scorpion venom using zymography and venom-specific antivenin
Published in Toxicon (Oxford) (15-09-2010)“…Hemiscorpius lepturus envenomation exhibits various pathological changes in the affected tissues, including skin, blood cells, cardiovascular and central…”
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Experimental intracerebral vaccination protects mouse from a neurotropic virus by attracting antibody secreting cells to the CNS
Published in Immunology letters (30-09-2011)“…Highlights ► We investigated the immune response in intracerebrally vaccinated mouse. ► Serum antibodies were highly produced in intracerebrally vaccinated…”
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The Hair Growth-Promoting Effect of Rumex japonicus Houtt. Extract
Published in Evidence-based complementary and alternative medicine (01-01-2016)“…Rumex japonicus Houtt. is traditionally used as a medicinal plant to treat patients suffering from skin disease in Korea. However, the beneficial effect of…”
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Necrotic neuronal cells induce inflammatory Schwann cell activation via TLR2 and TLR3: Implication in Wallerian degeneration
Published in Biochemical and biophysical research communications (24-11-2006)“…Schwann cells play an important role in peripheral nerve regeneration. Upon nerve injury, Schwann cells are activated and produce various proinflammatory…”
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