Search Results - "Lee, Henry HC"

New Therapeutic Approaches to Inherited Metabolic Pediatric Epilepsies by Pearl, Phillip L., Tokatly-Latzer, Itay, Lee, Henry HC, Rotenberg, Alexander

“…Treatment options for inherited metabolic epilepsies are rapidly expanding with advances in molecular biology and the genomic revolution. Traditional dietary…”
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Otx2 binding to perineuronal nets persistently regulates plasticity in the mature visual cortex by Beurdeley, Marine, Spatazza, Julien, Lee, Henry H C, Sugiyama, Sayaka, Bernard, Clémence, Di Nardo, Ariel A, Hensch, Takao K, Prochiantz, Alain

“…Specific transfer of (orthodenticle homeobox 2) Otx2 homeoprotein into GABAergic interneurons expressing parvalbumin (PV) is necessary and sufficient to open,…”
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Tyrosine phosphorylation regulates the membrane trafficking of the potassium chloride co-transporter KCC2 by Lee, Henry H.C., Jurd, Rachel, Moss, Stephen J.

“…The activity of the neuronal-specific potassium chloride co-transporter KCC2 allows neurons to maintain low intracellular Cl − concentrations. These low Cl −…”
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Choroid-Plexus-Derived Otx2 Homeoprotein Constrains Adult Cortical Plasticity by Spatazza, Julien, Lee, Henry H.C., Di Nardo, Ariel A., Tibaldi, Lorenzo, Joliot, Alain, Hensch, Takao K., Prochiantz, Alain

“…Brain plasticity is often restricted to critical periods in early life. Here, we show that a key regulator of this process in the visual cortex, Otx2…”
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Direct Protein Kinase C-dependent Phosphorylation Regulates the Cell Surface Stability and Activity of the Potassium Chloride Cotransporter KCC2 by Lee, Henry H.C., Walker, Joshua A., Williams, Jeffery R., Goodier, Richard J., Payne, John A., Moss, Stephen J.

“…The potassium chloride cotransporter KCC2 plays a major role in the maintenance of transmembrane chloride potential in mature neurons; thus KCC2 activity is…”
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Genetic Otx2 mis-localization delays critical period plasticity across brain regions by Lee, H H C, Bernard, C, Ye, Z, Acampora, D, Simeone, A, Prochiantz, A, Di Nardo, A A, Hensch, T K

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Hyperpolarizing GABAergic transmission depends on KCC2 function and membrane potential by Deeb, Tarek Z., Lee, Henry H.C., Walker, Joshua A., Davies, Paul A., Moss, Stephen J.

“…KCC2 comprises the major Cl- extruding mechanism in most adult neurons. Hyperpolarizing GABAergic transmission depends on KCC2 function. We recently…”
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Identification of the Sites for CaMK-II-dependent Phosphorylation of GABA sub(A) Receptors by Houston, Catriona M, Lee, Henry HC, Hosie, Alastair M, Moss, Stephen J, Smart, Trevor G

“…Phosphorylation can affect both the function and trafficking of GABA sub(A) receptors with significant consequences for neuronal excitability. Serine/threonine…”
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