Search Results - "Lee, Hee Seung"
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Tailoring Enantiomeric Chiral Channels in Metal‐Peptide Networks: A Novel Foldamer‐Based Approach for Host‐Guest Interactions
Published in Advanced materials (Weinheim) (01-12-2023)“…Designing chiral channels in organic frameworks presents an ongoing challenge due to the intricate control of size, shape, and functionality required. A novel…”
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Microglial MERTK eliminates phosphatidylserine‐displaying inhibitory post‐synapses
Published in The EMBO journal (02-08-2021)“…Glia contribute to synapse elimination through phagocytosis in the central nervous system. Despite the important roles of this process in development and…”
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Bottom-up and top-down modulation of multisensory integration
Published in Current opinion in neurobiology (01-10-2018)“…•Multisensory integration is modulated by bottom-up and top-down factors.•The core bottom-up features for multisensory integration are strength, location and…”
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Chiral Template‐Driven Macroscopic Chirality Control: Structure‐Second‐Harmonic Generation Properties Relationship
Published in European journal of inorganic chemistry (05-02-2021)“…Chirality is one of the most important topics in chemistry attributable to the peculiar stereochemical properties. Since the chirality belongs to one of the…”
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Conformational Adaptation of β‐Peptide Foldamers for the Formation of Metal–Peptide Frameworks
Published in Angewandte Chemie International Edition (03-01-2022)“…Metal‐coordinated frameworks derived from small peptidic ligands have received much attention thanks to peptides’ vast structural and functional diversity…”
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Wafer-scale single-crystal hexagonal boron nitride film via self-collimated grain formation
Published in Science (American Association for the Advancement of Science) (16-11-2018)“…Although polycrystalline hexagonal boron nitride (PC-hBN) has been realized, defects and grain boundaries still cause charge scatterings and trap sites,…”
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Crystalline Metal‐Peptide Networks: Structures, Applications, and Future Outlook
Published in Chembiochem : a European journal of chemical biology (17-01-2023)“…Metal‐peptide networks (MPNs), which are assembled from short peptides and metal ions, are considered one of the most fascinating metal‐organic coordinated…”
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The role of neuropeptide somatostatin in the brain and its application in treating neurological disorders
Published in Experimental & molecular medicine (01-03-2021)“…Somatostatin (SST) is a well-known neuropeptide that is expressed throughout the brain. In the cortex, SST is expressed in a subset of GABAergic neurons and is…”
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Fast modulation of visual perception by basal forebrain cholinergic neurons
Published in Nature neuroscience (01-12-2013)“…Cholinergic transmission from the basal forebrain provides neuromodulatory control over brain states such as wakefulness and sleep. Here the authors show that…”
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Versatile Post‐synthetic Modifications of Helical β‐Peptide Foldamers Derived from a Thioether‐Containing Cyclic β‐Amino Acid
Published in Angewandte Chemie International Edition (25-09-2023)“…We introduce a novel cyclic β‐amino acid, trans‐(3S,4R)‐4‐aminotetrahydrothiophene‐3‐carboxylic acid (ATTC), as a versatile building block for designing…”
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Tailoring Enantiomeric Chiral Channels in Metal‐Peptide Networks: A Novel Foldamer‐Based Approach for Host‐Guest Interactions (Adv. Mater. 52/2023)
Published in Advanced materials (Weinheim) (01-12-2023)“…Metal–Peptide Networks In article number 2305753, Hee‐Seung Lee and co‐workers craft enantiomeric chiral channels within metal–peptide networks (MPNs), tunable…”
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Neural Circuits for Goal-Directed Sensorimotor Transformations
Published in Trends in neurosciences (Regular ed.) (01-01-2019)“…Precisely wired neuronal circuits process sensory information in a learning- and context-dependent manner in order to govern behavior. Simple sensory…”
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Geomimetic Hydrothermal Synthesis of Polyimide‐Based Covalent Organic Frameworks
Published in Angewandte Chemie International Edition (21-01-2022)“…Despite its abundance, water is not widely used as a medium for organic reactions. However, under geothermal conditions, water exhibits unique physicochemical…”
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Facile preparation of flower-like NiCo2O4/three dimensional graphene foam hybrid for high performance supercapacitor electrodes
Published in Carbon (New York) (01-08-2015)Get full text
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Synthetic Foldamers: Rational Design of Advanced Structures with Diverse Applications
Published in ChemPlusChem (Weinheim, Germany) (01-08-2021)“…Fruitful Foldamers: Guest Editors Ivan Huc, Sunbum Kwon, and Hee‐Seung Lee discuss the development of the field and introduce this Special Collection on the…”
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A potent HNF4α agonist reveals that HNF4α controls genes important in inflammatory bowel disease and Paneth cells
Published in PloS one (01-04-2022)“…HNF4α has been implicated in IBD through a number of genome-wide association studies. Recently, we developed potent HNF4α agonists, including N-trans…”
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Anti‐inflammatory Glycocalyx‐Mimicking Nanoparticles for Colitis Treatment: Construction and In Vivo Evaluation
Published in Angewandte Chemie International Edition (21-08-2023)“…Common medications for treating inflammatory bowel disease (IBD) have limited therapeutic efficacy and severe adverse effects. This underscores the urgent need…”
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Distinct Roles of Parvalbumin- and Somatostatin-Expressing Interneurons in Working Memory
Published in Neuron (Cambridge, Mass.) (23-11-2016)“…Inhibitory interneurons are thought to play crucial roles in diverse brain functions. However, roles of different inhibitory interneuron subtypes in working…”
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Activation of specific interneurons improves V1 feature selectivity and visual perception
Published in Nature (London) (16-08-2012)“…Optogenetic activation of parvalbumin-expressing versus other classes of interneurons is found to have distinct effects on the response properties of…”
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Optimized stereoselective and scalable synthesis of five‐membered cyclic trans ‐β‐amino acid building blocks via reductive amination
Published in Bulletin of the Korean Chemical Society (01-12-2023)“…Abstract We present an optimized method for the stereoselective synthesis of five‐membered alicyclic and heterocyclic trans ‐β‐amino acid derivatives. The…”
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