Search Results - "Lee, Hee Gu"

TXNIP Maintains the Hematopoietic Cell Pool by Switching the Function of p53 under Oxidative Stress by Jung, Haiyoung, Kim, Mi Jeong, Kim, Dong Oh, Kim, Won Sam, Yoon, Sung-Jin, Park, Young-Jun, Yoon, Suk Ran, Kim, Tae-Don, Suh, Hyun-Woo, Yun, Sohyun, Min, Jeong-Ki, Lee, Hee Gu, Lee, Young Ho, Na, Hee-Jun, Lee, Dong Chul, Kim, Hyoung-Chin, Choi, Inpyo

“…Reactive oxygen species (ROS) are critical determinants of the fate of hematopoietic stem cells (HSCs) and hematopoiesis. Thioredoxin-interacting protein…”
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Opa-interacting protein 5 modulates docetaxel-induced cell death via regulation of mitophagy in gastric cancer by Kim, Tae Woo, Lee, Seon-Jin, Park, Young-Jun, Park, Sang Yoon, Oh, Byung Moo, Park, Yun Sun, Kim, Bo-Yeon, Lee, Young-Ha, Cho, Hee Jun, Yoon, Suk Ran, Choe, Yong-Kyung, Lee, Hee Gu

“…Damage to mitochondria induces mitophagy, a cellular process that is gaining interest for its therapeutic relevance to a variety of human diseases. However,…”
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Functional and clinical evidence for NDRG2 as a candidate suppressor of liver cancer metastasis by Lee, Dong Chul, Kang, Yun Kyung, Kim, Woo Ho, Jang, Ye Jin, Kim, Dong Joon, Park, In Young, Sohn, Bo Hwa, Sohn, Hyun Ahm, Lee, Hee Gu, Lim, Jong Seok, Kim, Jae Wha, Song, Eun Young, Kim, Dong Min, Lee, Mi-Ni, Oh, Goo Taeg, Kim, Soo Jung, Park, Kyung Chan, Yoo, Hyang Sook, Choi, Jong Young, Yeom, Young Il

“…We searched for potential suppressors of tumor metastasis by identifying the genes that are frequently down-regulated in hepatocellular carcinomas (HCC) while…”
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Apigenin Induces Autophagy and Cell Death by Targeting EZH2 under Hypoxia Conditions in Gastric Cancer Cells by Kim, Tae Woo, Lee, Hee Gu

“…Hypoxia is a major obstacle to gastric cancer (GC) therapy and leads to chemoresistance as GC cells are frequently exposed to the hypoxia environment…”
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CRP detection from serum for chip-based point-of-care testing system by Kim, Chang-Hoon, Ahn, Jae-Hyuk, Kim, Jee-Yeon, Choi, Ji-Min, Lim, Kyung-Choon, Jung Park, Tae, Su Heo, Nam, Gu Lee, Hee, Kim, Jong-Wan, Choi, Yang-Kyu

“…Most of point-of-care testing (POCT) to improve facilitates in diagnosis, treatment, and monitoring of patients. POCT technique has still remained a…”
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Dysregulation of Rho GTPases in Human Cancers by Jung, Haiyoung, Yoon, Suk Ran, Lim, Jeewon, Cho, Hee Jun, Lee, Hee Gu

“…Rho GTPases play central roles in numerous cellular processes, including cell motility, cell polarity, and cell cycle progression, by regulating actin…”
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6-Shogaol Overcomes Gefitinib Resistance via ER Stress in Ovarian Cancer Cells by Kim, Tae Woo, Lee, Hee Gu

“…In women, ovary cancer is already the fifth leading cause of mortality worldwide. The use of cancer therapies, such as surgery, radiotherapy, and chemotherapy,…”
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Identification of endothelial cell‐specific molecule‐1 as a potential serum marker for colorectal cancer by Ji, Na Young, Kim, Young‐Ho, Jang, Ye Jin, Kang, Yun Hee, Lee, Chung Il, Kim, Jae Wha, Yeom, Young Il, Chun, Ho Kyung, Choi, Yoon‐Ho, Kim, Joo Heon, Kim, Jong Wan, Lee, Hee Gu, Song, Eun Young

“…No ideal serum markers for screening colorectal cancer (CRC) have been identified. The aim of this study was to determine the usefulness of endothelial…”
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Interleukin-32 monoclonal antibodies for Immunohistochemistry, Western blotting, and ELISA by Kim, Ki-Hong, Shim, Jung-Hyun, Seo, Eun-Hee, Cho, Min-Chul, Kang, Jung-Woo, Kim, Soo-Hyun, Yu, Dae-Yeul, Song, Eun-Young, Lee, Hee-Gu, Sohn, Jung-Hoon, Kim, JinMan, Dinarello, Charles A., Yoon, Do-Young

“…The members of the IL-1 family play important roles in the development and pathogenesis of autoimmune and inflammatory diseases. Especially, IL-1 and IL-18…”
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Modulation of Immunosuppression by Oligonucleotide-Based Molecules and Small Molecules Targeting Myeloid-Derived Suppressor Cells by Lim, Jihyun, Lee, Aram, Lee, Hee Gu, Lim, Jong-Seok

“…Myeloid-derived suppressor cells (MDSCs) are immature myeloid cells that exert suppressive function on the immune response. MDSCs expand in tumor-bearing hosts…”
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Expression of NDRG2 is related to tumor progression and survival of gastric cancer patients through Fas-mediated cell death by Choi, Seung-Chul, Yoon, Suk Ran, Park, Yuk Pheel, Song, Eun Young, Kim, Jae Wha, Kim, Woo Ho, Yang, Young, Lim, Jong-Seok, Lee, Hee Gu

“…Although N-myc downstream regulated gene 2 (NDRG2) has been known to be a tumor suppressor gene, the function of this gene has not been elucidated. In the…”
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Prostaglandin E2 Secreted by Thyroid Cancer Cells Contributes to Immune Escape Through the Suppression of Natural Killer (NK) Cell Cytotoxicity and NK Cell Differentiation by Park, Arum, Lee, Yunhee, Kim, Mi Sun, Kang, Young Ju, Park, Young-Jun, Jung, Haiyoung, Kim, Tae-Don, Lee, Hee Gu, Choi, Inpyo, Yoon, Suk Ran

“…Natural killer (NK) cells play important roles in immune surveillance. However, the tumor microenvironment suppresses NK cell function and allows cancer cells…”
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Cullin 3/KCTD5 Promotes the Ubiqutination of Rho Guanine Nucleotide Dissociation Inhibitor 1 and Regulates Its Stability by Cho, Hee Jun, Ryu, Ki-Jun, Baek, Kyoung Eun, Lim, Jeewon, Kim, Taeyoung, Song, Chae Yeong, Yoo, Jiyun, Lee, Hee Gu

“…Rho guanine nucleotide dissociation inhibitor 1 (RhoGDI1) plays important roles in numerous cellular processes, including cell motility, adhesion, and…”
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Amino-terminal arginylation targets endoplasmic reticulum chaperone BiP for autophagy through p62 binding by Cha-Molstad, Hyunjoo, Sung, Ki Sa, Hwang, Joonsung, Kim, Kyoung A., Yu, Ji Eun, Yoo, Young Dong, Jang, Jun Min, Han, Dong Hoon, Molstad, Michael, Kim, Jung Gi, Lee, Yoon Jee, Zakrzewska, Adriana, Kim, Su-Hyeon, Kim, Sung Tae, Kim, Sun Yong, Lee, Hee Gu, Soung, Nak Kyun, Ahn, Jong Seog, Ciechanover, Aaron, Kim, Bo Yeon, Kwon, Yong Tae

“…We show that ATE1 -encoded Arg-transfer RNA transferase (R-transferase) of the N-end rule pathway mediates N-terminal arginylation of multiple endoplasmic…”
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G protein-coupled estrogen receptor-1 agonist induces chemotherapeutic effect via ER stress signaling in gastric cancer by Lee, Seon-Jin, Kim, Tae Woo, Park, Gyeong Lim, Hwang, Yo Sep, Cho, Hee Jun, Kim, Jong-Tae, Lee, Hee Gu

“…G protein-coupled estrogen receptor (GPER) is known to play an important role in hormone-associated cancers. G-1, a novel synthetic GPER agonist, has been…”
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A Double-Edged Sword: The Two Faces of PARylation by Kang, Mincheol, Park, Seojin, Park, Seong-Hoon, Lee, Hee Gu, Park, Jun Hong

“…Poly ADP-ribosylation (PARylation) is a post-translational modification process. Following the discovery of PARP-1, numerous studies have demonstrated the role…”
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Efficient Interleukin-21 Production by Optimization of Codon and Signal Peptide in Chinese Hamster Ovarian Cells by Cho, Hee Jun, Oh, Byung Moo, Kim, Jong-Tae, Lim, Jeewon, Park, Sang Yoon, Hwang, Yo Sep, Baek, Kyoung Eun, Kim, Bo-Yeon, Choi, Inpyo, Lee, Hee Gu

“…Interleukin-21 is a common γ-chain cytokine that controls the immune responses of B cells, T cells, and natural killer cells. Targeting IL-21 to strengthen the…”
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Regulation of Hematopoietic Stem Cell Fate and Malignancy by Cho, Hee Jun, Lee, Jungwoon, Yoon, Suk Ran, Lee, Hee Gu, Jung, Haiyoung

“…The regulation of hematopoietic stem cell (HSC) fate decision, whether they keep quiescence, self-renew, or differentiate into blood lineage cells, is critical…”
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Morin Hydrate Reverses Cisplatin Resistance by Impairing PARP1/HMGB1-Dependent Autophagy in Hepatocellular Carcinoma by Singh, Mahendra Pal, Cho, Hee Jun, Kim, Jong-Tae, Baek, Kyoung Eun, Lee, Hee Gu, Kang, Sun Chul

“…Chemoresistance is a major obstacle that limits the benefits of cisplatin-based chemotherapy in various cancers, including hepatocellular carcinoma…”
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Protective Effects of Crotonis Semen Extract against Sepsis through NF-κB Pathway Inhibition by Hwang, Yo Sep, Yoon, Hyang Ran, Park, Hyo-Min, Jang, Jun-Pil, Park, Jun Hong, Park, Seong-Hoon, Lim, Jong Seok, Cho, Hee Jun, Lee, Hee Gu

“…Sepsis is an inflammatory condition causing organ failure due to an uncontrolled immune response to infection and remains a significant challenge. Crotonis…”
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