Search Results - "Lee, Hayan"
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Piercing the dark matter: bioinformatics of long-range sequencing and mapping
Published in Nature reviews. Genetics (01-06-2018)“…Several new genomics technologies have become available that offer long-read sequencing or long-range mapping with higher throughput and higher resolution…”
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Multi-faceted epigenetic dysregulation of gene expression promotes esophageal squamous cell carcinoma
Published in Nature communications (22-07-2020)“…Epigenetic landscapes can shape physiologic and disease phenotypes. We used integrative, high resolution multi-omics methods to delineate the methylome…”
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Thiaoxaaza-Macrocyclic Chromoionophores as Mercury(II) Sensors: Synthesis and Color Modulation
Published in Organic letters (19-03-2009)“…Azo-coupled macrocyclic chromoionophores incorporating benzene (L1) and pyridine (L2) subunits were synthesized, respectively. In a cation-induced color change…”
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A Study on the Genetic Variations and Germination Characteristics of Rhododendron sobayakiense to Prepare for Climate Change Threat
Published in Forests (01-02-2024)“…Rhododendron sobayakiense is an endemic and near-threatened species (Korean Red List, NT) found in the alpine regions of South Korea that requires…”
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Hybrid assembly with long and short reads improves discovery of gene family expansions
Published in BMC genomics (19-07-2017)“…Long-read and short-read sequencing technologies offer competing advantages for eukaryotic genome sequencing projects. Combinations of both may be appropriate…”
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Candidate variants in TUB are associated with familial tremor
Published in PLoS genetics (21-09-2020)“…Essential tremor (ET) is the most common adult-onset movement disorder. In the present study, we performed whole exome sequencing of a large ET-affected family…”
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The Dormancy Types and Germination Characteristics of the Seeds of Berberis koreana Palibin, an Endemic Species of Korea
Published in Horticulturae (01-05-2023)“…Berberis koreana Palibin is an endemic plant native to Korea. In this study, we aimed to study the seed germination of this species using a water imbibition…”
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SplitMEM: a graphical algorithm for pan-genome analysis with suffix skips
Published in Bioinformatics (Oxford, England) (15-12-2014)“…Genomics is expanding from a single reference per species paradigm into a more comprehensive pan-genome approach that analyzes multiple individuals together. A…”
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On the Security of Intra-Car Wireless Sensor Networks
Published in 2009 IEEE 70th Vehicular Technology Conference Fall (01-09-2009)“…Due to the increasing oil prices, reducing the weight of future cars will be important. One way to do this is by replacing wired sensors and their cables with…”
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Conference Proceeding -
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Genomic dark matter: the reliability of short read mapping illustrated by the genome mappability score
Published in Bioinformatics (15-08-2012)“…Genome resequencing and short read mapping are two of the primary tools of genomics and are used for many important applications. The current state-of-the-art…”
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Reevaluating the capability of Taq DNA polymerase: long PCR amplification
Published in Protein and peptide letters (01-04-2007)“…We tested the ability of Taq DNA polymerase (Taq) to amplify long DNA fragments and showed that, if the conditions were set properly, Taq could successfully…”
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Lifelong physical activity is associated with promoter hypomethylation of genes involved in metabolism, myogenesis, contractile properties and oxidative stress resistance in aged human skeletal muscle
Published in Scientific reports (01-03-2019)“…Lifelong regular physical activity is associated with reduced risk of type 2 diabetes (T2D), maintenance of muscle mass and increased metabolic capacity…”
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Longitudinal linked-read sequencing reveals ecological and evolutionary responses of a human gut microbiome during antibiotic treatment
Published in Genome research (01-08-2021)“…Gut microbial communities can respond to antibiotic perturbations by rapidly altering their taxonomic and functional composition. However, little is known…”
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The pineapple genome and the evolution of CAM photosynthesis
Published in Nature genetics (01-12-2015)“…Ray Ming, Robert Paull, Qingyi Yu and colleagues report the genome sequences of two cultivated pineapple varieties and one wild pineapple relative. Their…”
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Comparison of the seed dormancy and germination characteristics of six Clematis species from South Korea
Published in Scientia horticulturae (03-01-2023)“…•Six Korean Clematis species display morphological or morphophysiological dormancy.•Germination indices are improved in Clematis seeds by 100 mg/L GA4+7…”
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Epigenetic balance ensures mechanistic control of MLL amplification and rearrangement
Published in Cell (12-10-2023)“…MLL/KMT2A amplifications and translocations are prevalent in infant, adult, and therapy-induced leukemia. However, the molecular contributor(s) to these…”
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TET1 and TDG Suppress Inflammatory Response in Intestinal Tumorigenesis: Implications for Colorectal Tumors With the CpG Island Methylator Phenotype
Published in Gastroenterology (New York, N.Y. 1943) (01-05-2023)“…Aberrant DNA methylation is frequent in colorectal cancer (CRC), but underlying mechanisms and pathologic consequences are poorly understood. We disrupted…”
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Apical receptors on M cells can be used as mucosal immune modulator (MUC9P.749)
Published in The Journal of immunology (1950) (01-05-2015)“…Abstract Intestinal epithelial cells which are exposed to microbes tightly restrict the influx of luminal antigens. They also contribute to establish the…”
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The Dormancy Types and Germination Characteristics of the Seeds of IBerberis koreana/I Palibin, an Endemic Species of Korea
Published in Horticulturae (01-05-2023)“…Berberis koreana Palibin is an endemic plant native to Korea. In this study, we aimed to study the seed germination of this species using a water imbibition…”
Get full text
Journal Article