Search Results - "Lee, Gyeongseok"

Novel piperazine-based ionizable lipid nanoparticles allow the repeated dose of mRNA to fibrotic lungs with improved potency and safety by Kim, Minjeong, Jeong, Michaela, Lee, Gyeongseok, Lee, Yeji, Park, Jeongeun, Jung, Hyein, Im, Seongeun, Yang, Joo-Sung, Kim, Kyungjin, Lee, Hyukjin

“…mRNA-based protein replacement therapy has received much attention as a novel intervention in clinical disease treatment. Lipid nanoparticles (LNPs) are widely…”
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Engineered lipid nanoparticles enable therapeutic gene silencing of GTSE1 for the treatment of liver fibrosis by Jeong, Michaela, Shin, Sumin, Lee, Gyeongseok, Lee, Yeji, Park, Seo Bhin, Kang, Jisoo, Lee, Young-Sun, Seo, Wonhyo, Lee, Hyukjin

“…Liver fibrosis is characterized by abnormal accumulation of extracellular matrix proteins, disrupting normal liver function. Despite its significant health…”
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Engineered Lipid Nanoparticles for the Treatment of Pulmonary Fibrosis by Regulating Epithelial‐Mesenchymal Transition in the Lungs by Jin, Hee, Jeong, Michaela, Lee, Gyeongseok, Kim, Minjeong, Yoo, Youngjo, Kim, Hyun Jin, Cho, Jaeho, Lee, Yun‐Sil, Lee, Hyukjin

“…Pulmonary fibrosis is a chronic and irreversible lung disease with limited therapeutic regimens. Advances in elucidating the pathophysiological mechanism and…”
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Development of Lipid Nanoparticle Formulation for the Repeated Administration of mRNA Therapeutics by Lee, Yeji, Jeong, Michaela, Lee, Gyeongseok, Park, Jeongeun, Jung, Hyein, Im, Seongeun, Lee, Hyukjin

“…During the COVID-19 pandemic, mRNA vaccines emerged as a rapid and effective solution for global immunization. The success of COVID-19 mRNA vaccines has…”
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