Search Results - "Lee, Flora"

Advances in CLIP Technologies for Studies of Protein-RNA Interactions by Lee, Flora C.Y., Ule, Jernej

“…RNA binding proteins (RBPs) regulate all aspects in the life cycle of RNA molecules. To elucidate the elements that guide RNA specificity, regulatory…”
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TDP-43 condensation properties specify its RNA-binding and regulatory repertoire by Hallegger, Martina, Chakrabarti, Anob M., Lee, Flora C.Y., Lee, Bo Lim, Amalietti, Aram G., Odeh, Hana M., Copley, Katie E., Rubien, Jack D., Portz, Bede, Kuret, Klara, Huppertz, Ina, Rau, Frédérique, Patani, Rickie, Fawzi, Nicolas L., Shorter, James, Luscombe, Nicholas M., Ule, Jernej

“…Mutations causing amyotrophic lateral sclerosis (ALS) often affect the condensation properties of RNA-binding proteins (RBPs). However, the role of RBP…”
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Cross-Regulation between TDP-43 and Paraspeckles Promotes Pluripotency-Differentiation Transition by Modic, Miha, Grosch, Markus, Rot, Gregor, Schirge, Silvia, Lepko, Tjasa, Yamazaki, Tomohiro, Lee, Flora C.Y., Rusha, Ejona, Shaposhnikov, Dmitry, Palo, Michael, Merl-Pham, Juliane, Cacchiarelli, Davide, Rogelj, Boris, Hauck, Stefanie M., von Mering, Christian, Meissner, Alexander, Lickert, Heiko, Hirose, Tetsuro, Ule, Jernej, Drukker, Micha

“…RNA-binding proteins (RBPs) and long non-coding RNAs (lncRNAs) are key regulators of gene expression, but their joint functions in coordinating cell fate…”
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Subcellular mRNA Localization Regulates Ribosome Biogenesis in Migrating Cells by Dermit, Maria, Dodel, Martin, Lee, Flora C Y, Azman, Muhammad S, Schwenzer, Hagen, Jones, J Louise, Blagden, Sarah P, Ule, Jernej, Mardakheh, Faraz K

“…Translation of ribosomal protein-coding mRNAs (RP-mRNAs) constitutes a key step in ribosome biogenesis, but the mechanisms that modulate RP-mRNA translation in…”
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A computationally-enhanced hiCLIP atlas reveals Staufen1-RNA binding features and links 3′ UTR structure to RNA metabolism by Chakrabarti, Anob M, Iosub, Ira A, Lee, Flora C Y, Ule, Jernej, Luscombe, Nicholas M

“…Abstract The structure of mRNA molecules plays an important role in its interactions with trans-acting factors, notably RNA binding proteins (RBPs), thus…”
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Poised PABP–RNA hubs implement signal-dependent mRNA decay in development by Modic, Miha, Kuret, Klara, Steinhauser, Sebastian, Faraway, Rupert, van Genderen, Emiel, Ruiz de Los Mozos, Igor, Novljan, Jona, Vičič, Žiga, Lee, Flora C. Y., ten Berge, Derk, Luscombe, Nicholas M., Ule, Jernej

“…Signaling pathways drive cell fate transitions largely by changing gene expression. However, the mechanisms for rapid and selective transcriptome rewiring in…”
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miR-182 Regulates Slit2-Mediated Axon Guidance by Modulating the Local Translation of a Specific mRNA by Bellon, Anaïs, Iyer, Archana, Bridi, Simone, Lee, Flora C.Y., Ovando-Vázquez, Cesaré, Corradi, Eloina, Longhi, Sara, Roccuzzo, Michela, Strohbuecker, Stephanie, Naik, Sindhu, Sarkies, Peter, Miska, Eric, Abreu-Goodger, Cei, Holt, Christine E., Baudet, Marie-Laure

“…During brain wiring, cue-induced axon behaviors such as directional steering and branching are aided by localized mRNA translation. Different guidance cues…”
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HNRNPH1 regulates the neuroprotective cold‐shock protein RBM3 expression through poison exon exclusion by Lin, Julie Qiaojin, Khuperkar, Deepak, Pavlou, Sofia, Makarchuk, Stanislaw, Patikas, Nikolaos, Lee, Flora CY, Zbiegly, Julia M, Kang, Jianning, Field, Sarah F, Bailey, David MD, Freeman, Joshua L, Ule, Jernej, Metzakopian, Emmanouil, Ruepp, Marc‐David, Mallucci, Giovanna R

“…Enhanced expression of the cold‐shock protein RNA binding motif 3 (RBM3) is highly neuroprotective both in vitro and in vivo . Whilst upstream signalling…”
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RGS4 RNA Secondary Structure Mediates Staufen2 RNP Assembly in Neurons by Fernández-Moya, Sandra M, Ehses, Janina, Bauer, Karl E, Schieweck, Rico, Chakrabarti, Anob M, Lee, Flora C Y, Illig, Christin, Luscombe, Nicholas M, Harner, Max, Ule, Jernej, Kiebler, Michael A

“…RNA-binding proteins (RBPs) act as posttranscriptional regulators controlling the fate of target mRNAs. Unraveling how RNAs are recognized by RBPs and in turn…”
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Alaska Native Parents' Decision-Making About Food, Beverages, and Screen Time for Young Children: Formative Insights From the "Got Neqpiaq?" Project by Ohle, Kathryn A, Koller, Kathryn R, Walch, Amanda K, Lee, Flora R, Palmer, Lea, Nu, Jennifer, Thomas, Timothy K

“…With rising childhood obesity rates, ensuring children adopt healthy habits early is imperative. Given the unique context for Alaska Native families living in…”
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Adapting a Financial Incentives Intervention for Smoking Cessation With Alaska Native Families: Phase 1 Qualitative Research to Inform the Aniqsaaq (To Breathe) Study by Sinicrope, Pamela S, Tranby, Brianna N, Young, Antonia M, Koller, Kathryn R, King, Diane K, Lee, Flora R, Sabaque, Corinna V, Prochaska, Judith J, Borah, Bijan J, Decker, Paul A, McDonell, Michael G, Stillwater, Barbara, Thomas, Timothy K, Patten, Christi A

“…Alaska Native and American Indian (ANAI) peoples in Alaska currently experience a disproportionate burden of morbidity and mortality from tobacco cigarette…”
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Alaska Native Parents' Decision-Making About Food, Beverages, and Screen Time for Young Children by Ohle, Kathryn A, Koller, Kathryn R, Walch, Amanda K, Lee, Flora R, Palmer, Lea, Nu, Jennifer, Thomas, Timothy K

“…With rising childhood obesity rates, ensuring children adopt healthy habits early is imperative. Given the unique context for Alaska Native families living in…”
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Transient developmental imbalance of cortical interneuron subtypes presages long-term changes in behavior by Magno, Lorenza, Asgarian, Zeinab, Pendolino, Valentina, Velona, Theodora, Mackintosh, Albert, Lee, Flora, Stryjewska, Agata, Zimmer, Celine, Guillemot, François, Farrant, Mark, Clark, Beverley, Kessaris, Nicoletta

“…Cortical GABAergic interneurons are generated in large numbers in the ganglionic eminences and migrate into the cerebral cortex during embryogenesis. At early…”
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Storekeeper perspectives on improving dietary intake in 12 rural remote western Alaska communities: the "Got Neqpiaq?" project by Koller, Kathryn R., Flanagan, Christie A., Nu, Jennifer, Lee, Flora R., Desnoyers, Christine, Walch, Amanda, Alexie, Lucinda, Bersamin, Andrea, Thomas, Timothy K.

“…Low intake of fruits and vegetables and high intake of sugar-sweetened beverages persists as a public health concern in rural remote Alaska Native (AN)…”
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Impact of Assistance Programs on Indigenous Ways of Life in 12 Rural Remote Western Alaska Native Communities: Elder Perspectives Shared in Formative Work for the "Got Neqpiaq?" Project by Walch, Amanda K., Ohle, Kathryn A., Koller, Kathryn R., Alexie, Lucinda, Lee, Flora, Palmer, Lea, Nu, Jennifer, Thomas, Timothy K., Bersamin, Andrea

“…For more than 50 years, government programmes in the USA have been in place to help those in need have consistent access to food and education. However,…”
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Dietary fibre to reduce colon cancer risk in Alaska Native people: the Alaska FIRST randomised clinical trial protocol by Koller, Kathryn R, Wilson, Annette, Normolle, Daniel P, Nicholson, Jeremy K, Li, Jia V, Kinross, James, Lee, Flora R, Flanagan, Christie A, Merculieff, Zoe T, Iyer, Priya, Lammers, Daniela L, Thomas, Timothy K, O'Keefe, Stephen J D

“…IntroductionDiet, shown to impact colorectal cancer (CRC) risk, is a modifiable environmental factor. Fibre foods fermented by gut microbiota produce…”
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Aniqsaaq (To Breathe): Study protocol to develop and evaluate an Alaska Native family-based financial incentive intervention for smoking cessation by Patten, Christi A., Koller, Kathryn R., King, Diane K., Prochaska, Judith J., Sinicrope, Pamela S., McDonell, Michael G., Decker, Paul A., Lee, Flora R., Fosi, Janessa K., Young, Antonia M., Sabaque, Corinna V., Brown, Ashley R., Borah, Bijan J., Thomas, Timothy K.

“…Alaska Native and American Indian (ANAI) communities in Alaska are disproportionately affected by commercial tobacco use. Financial incentive interventions…”
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Amelioration of experimental colitis by Astragalus membranaceus through anti-oxidation and inhibition of adhesion molecule synthesis by Ko, Joshua-Ka-Shun, Lam, Flora-Ying-Lee, Cheung, Andrew-Pok-Lap

“…AIM： To investigate the protective effects of Astragalus membranaceus （Am） against hapten-induced colitis in male Sprague-Dawley rats as well as its underlying…”
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Effect of LSVT on Lexical Tone in Speakers with Parkinson’s Disease by Chow, Mia M.-N., Lee, Flora P.-H., Kwan, Lorinda C., Whitehill, Tara L.

“…Lee Silverman Voice Treatment (LSVT) has well-documented treatment efficacy for individuals with hypokinetic dysarthria associated with Parkinson's disease…”
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1281 TARGETED GENE EXPRESSION AND CONCENTRATIONS OF SHORTCHAIN FATTY ACIDS IN RESPONSE TO HIGH FIBER SUPPLEMENTATION: RESULTS OF THE ALASKA FIBER INTERVENTION RESEARCH STUDY (FIRST) by Cifuentes, Lizeth, Perez, Miriam R., Eberhart, B.L., Lee, Flora, Day, Gretchen, Ocvirk, Soren, Thomas, Timothy, O'Keefe, Stephen J.

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