Search Results - "Lee, Eunjoo H"
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Anti-inflammatory effects of crocin and crocetin in rat brain microglial cells
Published in European journal of pharmacology (01-12-2010)“…Microglial cells play critical roles in the immune and inflammatory responses of the central nervous system (CNS). Under pathological conditions, the…”
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2
Synthesis of 1,4-Dialkoxynaphthalene-Based Imidazolium Salts and Their Cytotoxicity in Cancer Cell Lines
Published in International journal of molecular sciences (01-02-2023)“…In this study, we designed and synthesized novel 1,4-dialkoxynaphthalene-2-alkyl imidazolium salt (IMS) derivatives containing both 1,4-dialkoxynaphthalene and…”
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Inhibitory effect of 5,6-dihydroergosteol-glucoside on atopic dermatitis-like skin lesions via suppression of NF-κB and STAT activation
Published in Journal of dermatological science (01-09-2015)“…Highlights • DHE-Glc attenuates AD-like skin inflammatory symptoms in mice. • DHE-Glc suppresses TNF-α/IFN-γ induced TARC and MDC in HaCaT keratinocytes. •…”
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4
Mechanism of glucocorticoid-induced oxidative stress in rat hippocampal slice cultures
Published in Canadian journal of physiology and pharmacology (01-06-2009)“…Prolonged stress results in elevation of glucocorticoid (GC) hormones, which can have deleterious effects in the brain. The hippocampus, which has a high…”
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Fine particulate matter (PM2.5) inhibits ciliogenesis by increasing SPRR3 expression via c-Jun activation in RPE cells and skin keratinocytes
Published in Scientific reports (08-03-2019)“…Exposure to fine particulate matter (PM) with diameter <2.5 µm (PM2.5) causes epithelium injury and endothelial dysfunction. Primary cilia are sensory…”
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The Methoxyflavonoid Isosakuranetin Suppresses UV-B-Induced Matrix Metalloproteinase-1 Expression and Collagen Degradation Relevant for Skin Photoaging
Published in International journal of molecular sciences (01-09-2016)“…Solar ultraviolet (UV) radiation is a main extrinsic factor for skin aging. Chronic exposure of the skin to UV radiation causes the induction of matrix…”
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7
Genipin inhibits the inflammatory response of rat brain microglial cells
Published in International immunopharmacology (01-04-2010)“…Microglia are the prime effectors in immune and inflammatory responses of the central nervous system (CNS). Under pathological conditions, the activation of…”
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Inhibitory effects of arbutin on melanin biosynthesis of α-melanocyte stimulating hormone-induced hyperpigmentation in cultured brownish guinea pig skin tissues
Published in Archives of pharmacal research (01-03-2009)“…Arbutin has been used as a whitening agent in cosmetic products. Melanin, the major pigment that gives color to skin, may be over-produced with sun exposure or…”
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Anti-Inflammatory Effect of Cudrania tricuspidata Extract and Stewartia koreana Extract Mixture in a Collagen-Induced Arthritis Mouse Model
Published in Applied sciences (01-07-2021)“…Cudrania tricuspidata extracts (CTE) and Stewartia koreana extracts (SKE) are viable drugs for managing inflammation. We investigated the nitric oxide levels…”
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10
Inhibition of autophagy suppresses sertraline-mediated primary ciliogenesis in retinal pigment epithelium cells
Published in PloS one (11-02-2015)“…Primary cilia are conserved cellular organelles that regulate diverse signaling pathways. Autophagy is a complex process of cellular degradation and recycling…”
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11
Lipopolysaccharide induces hypoxia-inducible factor-1 alpha mRNA expression and activation via NADPH oxidase and Sp1-dependent pathway in BV2 murine microglial cells
Published in Neuroscience letters (31-01-2008)“…Hypoxia-inducible factor-1 (HIF-1), the key transcription factor of hypoxia-inducible genes, is known to be involved in inflammation and immune response, but…”
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12
The multi-herbal medicine Gongjin-dan enhances memory and learning tasks via NGF regulation
Published in Neuroscience letters (11-12-2009)“…Nerve growth factor (NGF) decreases degeneration of cholinergic neurons, improves memory loss, and increases long-term potentiation and learning tasks…”
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13
The water extract of adlay seed (Coix lachrymajobi var. mayuen) exhibits anti-obesity effects through neuroendocrine modulation
Published in The American journal of Chinese medicine (1979) (2007)“…To find out whether the immunohistochemical expression of neuropeptid Y (NPY) and leptin receptor (LR) in the rat hypothalamus is influenced by adlay seed…”
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14
Depletion of nucleophosmin via transglutaminase 2 cross-linking increases drug resistance in cancer cells
Published in Cancer letters (18-02-2009)“…Abstract It has been suggested that nucleophosmin has an anti-apoptotic function via Bax binding. We found that nucleophosmin is a substrate of…”
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15
Cynandione A inhibits lipopolysaccharide-induced cell adhesion via suppression of the protein expression of VCAM-1 in human endothelial cells
Published in International journal of molecular medicine (01-03-2018)“…Cynandione A (CA) is one of the most active compounds in the roots of Cynanchum wilfordii, the extracts of which have been used extensively in East Asia to…”
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Tetramethylpyrazine, a natural alkaloid, attenuates pro-inflammatory mediators induced by amyloid β and interferon-γ in rat brain microglia
Published in European journal of pharmacology (05-10-2014)“…Neuroinflammation has been consistently reported as a pathological hallmark of Alzheimer׳s disease and other neurodegenerative diseases. Microglial cells are…”
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17
Down-regulation of mortalin exacerbates Aβ-mediated mitochondrial fragmentation and dysfunction
Published in The Journal of biological chemistry (24-01-2014)“…Mitochondrial dynamics greatly influence the biogenesis and morphology of mitochondria. Mitochondria are particularly important in neurons, which have a high…”
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18
Role of nitric oxide synthase inhibitors and NMDA receptor antagonist in nicotine-induced behavioral sensitization in the rat
Published in European journal of pharmacology (17-05-2002)“…Repeated injections of nicotine are well known to produce progressively larger increases in locomotor activity, an effect defined as behavioral sensitization…”
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Effect of electroacupuncture on the stress-induced changes in brain-derived neurotrophic factor expression in rat hippocampus
Published in Neuroscience letters (25-01-2002)“…Stress induces neuronal atrophy and death especially in the hippocampus. Alterations in the expression of neurotrophic factors are implicated in stress-induced…”
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Paeoniflorin, a monoterpene glycoside, attenuates lipopolysaccharide-induced neuronal injury and brain microglial inflammatory response
Published in Biotechnology letters (01-08-2013)“…Chronic activation of microglial cells endangers neuronal survival through the release of various proinflammatory and neurotoxic factors. Paeoniflorin (PF), a…”
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