Search Results - "Lee, Eun K."

Peripheral cannabinoid 1 receptor blockade mitigates adipose tissue inflammation via NLRP3 inflammasome in mouse models of obesity by Han, Ji H., Shin, Hanho, Rho, Jun G., Kim, Jung‐Eun, Son, Dong H., Yoon, Juhwan, Lee, Yong J., Park, Jung‐Hyuck, Song, Byung J., Choi, Chang‐Sik, Yoon, Seul G., Kim, Il Y., Lee, Eun K., Seong, Je K., Kim, Ki W., Kim, Wook

“…Aim To analyze the metabolic parameters and adipose tissue inflammation via NLRP3 inflammasome following chronic treatment of mouse models of obesity with…”
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Long-term Survival of the Juvenile Lethal Arginase-deficient Mouse With AAV Gene Therapy by Lee, Eun K., Hu, Chuhong, Bhargava, Ragini, Rozengurt, Nora, Stout, David, Grody, Wayne W, Cederbaum, Stephen D, Lipshutz, Gerald S

“…Arginase deficiency is characterized by hyperargininemia and infrequent episodes of hyperammonemia. Human patients suffer from neurological impairment with…”
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Oncogenic potential of CK2α and its regulatory role in EGF‐induced HDAC2 expression in human liver cancer by Kim, Hyung S., Chang, Young G., Bae, Hyun J., Eun, Jung W., Shen, Qingyu, Park, Se J., Shin, Woo C., Lee, Eun K., Park, Soha, Ahn, Young M., Park, Won S., Lee, Jung Y., Nam, Suk W.

“…Histone deacetylase 2 (HDAC2) is aberrantly regulated and plays a pivotal role in the development of hepatocellular carcinoma (HCC) through regulation of…”
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Discovery of a Novel Series of Potent Non-Nucleoside Inhibitors of Hepatitis C Virus NS5B by Schoenfeld, Ryan C, Bourdet, David L, Brameld, Ken A, Chin, Elbert, de Vicente, Javier, Fung, Amy, Harris, Seth F, Lee, Eun K, Le Pogam, Sophie, Leveque, Vincent, Li, Jim, Lui, Alfred S.-T, Najera, Isabel, Rajyaguru, Sonal, Sangi, Michael, Steiner, Sandra, Talamas, Francisco X, Taygerly, Joshua P, Zhao, Junping

“…Hepatitis C virus (HCV) is a major global public health problem. While the current standard of care, a direct-acting antiviral (DAA) protease inhibitor taken…”
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Discovery of N‑[4-[6-tert-Butyl-5-methoxy-8-(6-methoxy-2-oxo‑1H‑pyridin-3-yl)-3-quinolyl]phenyl]­methanesulfonamide (RG7109), a Potent Inhibitor of the Hepatitis C Virus NS5B Polymerase by Talamas, Francisco X., Abbot, Sarah C., Anand, Shalini, Brameld, Ken A., Carter, David S., Chen, Jun, Davis, Dana, de Vicente, Javier, Fung, Amy D., Gong, Leyi, Harris, Seth F., Inbar, Petra, Labadie, Sharada S., Lee, Eun K., Lemoine, Remy, Le Pogam, Sophie, Leveque, Vincent, Li, Jim, McIntosh, Joel, Nájera, Isabel, Park, Jaehyeon, Railkar, Aruna, Rajyaguru, Sonal, Sangi, Michael, Schoenfeld, Ryan C., Staben, Leanna R., Tan, Yunchou, Taygerly, Joshua P., Villaseñor, Armando G., Weller, Paul E.

“…In the past few years, there have been many advances in the efforts to cure patients with hepatitis C virus (HCV). The ultimate goal of these efforts is to…”
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Novel hexahydropyrrolo[3,4- c]pyrrole CCR5 antagonists by Rotstein, David M., Melville, Chris R., Padilla, Fernando, Cournoyer, Dick, Lee, Eun K., Lemoine, Remy, Petersen, Ann C., Setti, Lina Q., Wanner, Jutta, Chen, Lijing, Filonova, Lubov, Loughhead, David G., Manka, Jason, Lin, Xiao-Fa, Gleason, Shelley, Sankuratri, Surya, Ji, Changhua, deRosier, Andre, Dioszegi, Marianna, Heilek, Gabrielle, Jekle, Andreas, Berry, Pamela, Mau, Cheng-I, Weller, Paul

“…Utilizing a high-throughput screening lead as a starting point, an information-based approach led to the discovery of a novel series of CCR5 antagonists,…”
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Ascorbic acid suppresses the 2,3,7,8-tetrachloridibenxo- p-dioxin (TCDD)-induced CYP1A1 expression in human HepG2 cells by Chang, Hee J., Park, Jung S., Lee, Eun K., Kim, Mi H., Baek, Min K., Kim, Hyeong R., Jeong, Hye G., Choi, Seok Y., Jung, Young D.

“…The mechanisms involving the inhibitory effects of ascorbic acid (AA) on carcinogenesis have not fully defined, except for its free-radical scavenging activity…”
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A direct test of the reductionist approach to structural studies of calmodulin activity: relevance of peptide models of target proteins by Kranz, James K, Lee, Eun K, Nairn, Angus C, Wand, A Joshua

“…Ca(2+)-saturated calmodulin (CaM) directly associates with and activates CaM-dependent protein kinase I (CaMKI) through interactions with a short sequence in…”
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Cripto-1 overexpression is involved in the tumorigenesis of gastric-type and pancreatobiliary-type intraductal papillary mucinous neoplasms of the pancreas by HONG, Sung P, LEE, Eun K, PARK, Jeong Y, JEON, Tae J, BANG, Seungmin, PARK, Seungwoo, CHUNG, Jae B, LEE, Woo J, KIM, Hoguen, SONG, Si Y

“…Human Cripto-1, a membrane-bound protein, plays an important role during early embryogenesis and has oncogenic properties, including cell transformation and…”
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Molecular cloning of leukotactin-1: a novel human beta-chemokine, a chemoattractant for neutrophils, monocytes, and lymphocytes, and a potent agonist at CC chemokine receptors 1 and 3 by Youn, BS, Zhang, SM, Lee, EK, Park, DH, Broxmeyer, HE, Murphy, PM, Locati, M, Pease, JE, Kim, KK, Antol, K, Kwon, BS

“…A new member of human beta-chemokine cDNA was isolated and named leukotactin-1 (Lkn-1). Lkn-1, along with murine macrophage inflammatory protein-related…”
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Reducing Datacenter Compute Carbon Footprint by Harnessing the Power of Specialization: Principles, Metrics, Challenges and Opportunities by Eilam, Tamar, Bose, Pradip, Carloni, Luca P., Cidon, Asaf, Franke, Hubertus, Kim, Martha A., Lee, Eun K., Naghshineh, Mahmoud, Parida, Pritish, Stein, Clifford S., Tantawi, Asser N.

“…Computing is an indispensable tool in addressing climate change, but it also contributes to a significant and steadily increasing carbon footprint, partly due…”
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A Direct Test of the Reductionist Approach to Structural Studies of Calmodulin Activity by Kranz, James K., Lee, Eun K., Nairn, Angus C., Wand, A. Joshua

“…Ca2+-saturated calmodulin (CaM) directly associates with and activates CaM-dependent protein kinase I (CaMKI) through interactions with a short sequence in its…”
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EVALUATION OF THE APPLICABLE REACTIVITY RANGE OF A REACTIVITY COMPUTER FOR A CANDU-6 REACTOR by LEE, EUN KI, PARK, DONG HWAN, LEE, WHAN SOO

“…Recently, a CANDU digital reactivity computer system (CDRCS) to measure the worth of the liquid zone controller in a CANDU-6 was developed and successfully…”
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Cover Image, Volume 20, Issue 9 by Han, Ji H., Shin, Hanho, Rho, Jun G., Kim, Jung‐Eun, Son, Dong H., Yoon, Juhwan, Lee, Yong J., Park, Jung‐Hyuck, Song, Byung J., Choi, Chang‐Sik, Yoon, Seul G., Kim, Il Y., Lee, Eun K., Seong, Je K., Kim, Ki W., Kim, Wook

“…The cover image, by Ji H. Han et al., is based on the Original Article Peripheral cannabinoid 1 receptor blockade mitigates adipose tissue inflammation via…”
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AAV-based gene therapy prevents neuropathology and results in normal cognitive development in the hyperargininemic mouse by Lee, E K, Hu, C, Bhargava, R, Ponnusamy, R, Park, H, Novicoff, S, Rozengurt, N, Marescau, B, De Deyn, P, Stout, D, Schlichting, L, Grody, W W, Cederbaum, S D, Lipshutz, G S

“…Complete arginase I deficiency is the least severe urea cycle disorder, characterized by hyperargininemia and infrequent episodes of hyperammonemia. Patients…”
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IDENTIFICATION OF HURDLES FOR IMPROVING STORAGE STABILITY OF BRAISED KIDNEY BEANS, A KOREAN SEASONED SIDE DISH by LEE, KI-EUN, AN, DUCK SOON, LYU, EUN SOON, CHUNG, SUN KYUNG, LEE, DONG SUN

“…The aim of this study was to identify factors affecting the preservation of braised kidney beans, a traditional Korean side dish, to extend its shelf life. The…”
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Caspase Activation and Extracellular Signal-Regulated Kinase/Akt Inhibition Were Involved in Luteolin-Induced Apoptosis in Lewis Lung Carcinoma Cells by KIM, JIN-HYUNG, LEE, EUN-OK, LEE, HYO-JUNG, KU, JIN-SOOK, LEE, MIN-HO, YANG, DEOK-CHUN, KIM, SUNG-HOON

“…:  Luteolin was isolated from Scutellaria barbata D. Don (S. barbata). In the present study, we examined the underlying molecular mechanism of luteolin and its…”
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Long-term Survival of the Juvenile Lethal Arginase-deficient Mouse With AAV Gene Therapy by Lee, Eun K, Hu, Chuhong, Bhargava, Ragini, Rozengurt, Nora, Stout, David, Grody, Wayne W, Cederbaum, Stephen D, Lipshutz, Gerald S

“…Arginase deficiency is characterized by hyperargininemia and infrequent episodes of hyperammonemia. Human patients suffer from neurological impairment with…”
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Oncogenic potential of CK2[alpha] and its regulatory role in EGF-induced HDAC2 expression in human liver cancer by Kim, Hyung S, Chang, Young G, Bae, Hyun J, Eun, Jung W, Shen, Qingyu, Park, Se J, Shin, Woo C, Lee, Eun K, Park, Soha, Ahn, Young M, Park, Won S, Lee, Jung Y, Nam, Suk W

“…Histone deacetylase 2 (HDAC2) is aberrantly regulated and plays a pivotal role in the development of hepatocellular carcinoma (HCC) through regulation of…”
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Oncogenic potential of CK 2α and its regulatory role in EGF ‐induced HDAC 2 expression in human liver cancer by Kim, Hyung S., Chang, Young G., Bae, Hyun J., Eun, Jung W., Shen, Qingyu, Park, Se J., Shin, Woo C., Lee, Eun K., Park, Soha, Ahn, Young M., Park, Won S., Lee, Jung Y., Nam, Suk W.

“…Histone deacetylase 2 ( HDAC 2) is aberrantly regulated and plays a pivotal role in the development of hepatocellular carcinoma ( HCC ) through regulation of…”
Get full text