Search Results - "Lee, Eun Ji"

Transcriptional and Epigenomic Regulation of Adipogenesis by Lee, Ji-Eun, Schmidt, Hannah, Lai, Binbin, Ge, Kai

“…Understanding adipogenesis, the process of adipocyte development, may provide new ways to treat obesity and related metabolic diseases. Adipogenesis is…”
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Comprehensive understanding of risk and protective factors related to adolescent pregnancy in low- and middle-income countries: A systematic review by Chung, Hye Won, Kim, Eun Mee, Lee, Ji-Eun

“…Adolescent pregnancy causes serious problems not only for girls, but also for their family, and society. This study aimed to understand factors related to…”
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Olfactory function in mild cognitive impairment and Alzheimer's disease: A meta‐analysis by Jung, Hahn Jin, Shin, In‐Soo, Lee, Ji‐Eun

“…Objective Olfactory function is altered in mild cognitive impairment (MCI) and Alzheimer's disease (AD); therefore, it may serve as a useful tool for the early…”
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Student profiles based on in‐game performance and help‐seeking behaviours in an online mathematics game by Norum, Reilly, Lee, Ji‐Eun, Ottmar, Erin, Harrison, Lane

“…Well‐designed online educational games can improve students' math knowledge, skills and engagement; however, more research is needed to understand how to…”
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Disruption of KMT2D perturbs germinal center B cell development and promotes lymphomagenesis by Zhang, Jiyuan, Dominguez-Sola, David, Hussein, Shafinaz, Lee, Ji-Eun, Holmes, Antony B, Bansal, Mukesh, Vlasevska, Sofija, Mo, Tongwei, Tang, Hongyan, Basso, Katia, Ge, Kai, Dalla-Favera, Riccardo, Pasqualucci, Laura

“…Two studies demonstrate that the methyltransferase KMT2D, which is recurrently mutated in several types of human B cell lymphoma, suppresses tumorigenesis by…”
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Distinct roles of GCN5/PCAF-mediated H3K9ac and CBP/p300-mediated H3K18/27ac in nuclear receptor transactivation by Jin, Qihuang, Yu, Li-Rong, Wang, Lifeng, Zhang, Zhijing, Kasper, Lawryn H, Lee, Ji-Eun, Wang, Chaochen, Brindle, Paul K, Dent, Sharon Y R, Ge, Kai

“…Histone acetyltransferases (HATs) GCN5 and PCAF (GCN5/PCAF) and CBP and p300 (CBP/p300) are transcription co‐activators. However, how these two distinct…”
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MLL3/MLL4 are required for CBP/p300 binding on enhancers and super-enhancer formation in brown adipogenesis by Lai, Binbin, Lee, Ji-Eun, Jang, Younghoon, Wang, Lifeng, Peng, Weiqun, Ge, Kai

“…Histone H3K4me1/2 methyltransferases MLL3/MLL4 and H3K27 acetyltransferases CBP/p300 are major enhancer epigenomic writers. To understand how these epigenomic…”
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Brd4 binds to active enhancers to control cell identity gene induction in adipogenesis and myogenesis by Lee, Ji-Eun, Park, Young-Kwon, Park, Sarah, Jang, Younghoon, Waring, Nicholas, Dey, Anup, Ozato, Keiko, Lai, Binbin, Peng, Weiqun, Ge, Kai

“…The epigenomic reader Brd4 is an important drug target for cancers. However, its role in cell differentiation and animal development remains largely unclear…”
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Histone H3K9 methyltransferase G9a represses PPARγ expression and adipogenesis by Wang, Lifeng, Xu, Shiliyang, Lee, Ji-Eun, Baldridge, Anne, Grullon, Sean, Peng, Weiqun, Ge, Kai

“…PPARγ promotes adipogenesis while Wnt proteins inhibit adipogenesis. However, the mechanisms that control expression of these positive and negative master…”
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Replication fork stability confers chemoresistance in BRCA-deficient cells by Ray Chaudhuri, Arnab, Callen, Elsa, Ding, Xia, Gogola, Ewa, Duarte, Alexandra A., Lee, Ji-Eun, Wong, Nancy, Lafarga, Vanessa, Calvo, Jennifer A., Panzarino, Nicholas J., John, Sam, Day, Amanda, Crespo, Anna Vidal, Shen, Binghui, Starnes, Linda M., Ruiter, Julian R. de, Daniel, Jeremy A., Konstantinopoulos, Panagiotis A., Cortez, David, Cantor, Sharon B., Fernandez-Capetillo, Oscar, Ge, Kai, Jonkers, Jos, Rottenberg, Sven, Sharan, Shyam K., Nussenzweig, André

“…Cells deficient in the Brca1 and Brca2 genes have reduced capacity to repair DNA double-strand breaks by homologous recombination and consequently are…”
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A Preference-Driven Smart Home Service for the Elderly’s Biophilic Experience by Lee, Eun-Ji, Park, Sung-Jun

“…Smart home services (SHS) should support the positive experiences of the elderly in homes with a focus on getting closer to nature. The study identified the…”
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Gut microbiome diversity and function during hibernation and spring emergence in an aquatic frog by Lee, Ji-Eun, Park, Jun-Kyu, Do, Yuno

“…The gut microbiota maintains a deeply symbiotic relationship with host physiology, intricately engaging with both internal (endogenous) and external…”
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Opposing Functions of BRD4 Isoforms in Breast Cancer by Wu, Shwu-Yuan, Lee, Chien-Fei, Lai, Hsien-Tsung, Yu, Cheng-Tai, Lee, Ji-Eun, Zuo, Hao, Tsai, Sophia Y., Tsai, Ming-Jer, Ge, Kai, Wan, Yihong, Chiang, Cheng-Ming

“…Bromodomain-containing protein 4 (BRD4) is a cancer therapeutic target in ongoing clinical trials disrupting primarily BRD4-regulated transcription programs…”
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Hepatic triglyceride accumulation via endoplasmic reticulum stress-induced SREBP-1 activation is regulated by ceramide synthases by Kim, Ye-Ryung, Lee, Eun-Ji, Shin, Kyong-Oh, Kim, Min Hee, Pewzner-Jung, Yael, Lee, Yong-Moon, Park, Joo-Won, Futerman, Anthony H., Park, Woo-Jae

“…The endoplasmic reticulum (ER) is not only important for protein synthesis and folding but is also crucial for lipid synthesis and metabolism. In the current…”
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UTX regulates mesoderm differentiation of embryonic stem cells independent of H3K27 demethylase activity by Wang, Chaochen, Lee, Ji-Eun, Cho, Young-Wook, Xiao, Ying, Jin, Qihuang, Liu, Chengyu, Ge, Kai

“…To investigate the role of histone H3K27 demethylase UTX in embryonic stem (ES) cell differentiation, we have generated UTX knockout (KO) and enzyme-dead…”
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Continued Journey: Women’s Travel Kasa in Early Twentieth Century Korea by Ji-Eun LEE

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Single‐Molecule Two‐Color Coincidence Detection of Unlabeled alpha‐Synuclein Aggregates by Chappard, Alexandre, Leighton, Craig, Saleeb, Rebecca S., Jeacock, Kiani, Ball, Sarah R., Morris, Katie, Kantelberg, Owen, Lee, Ji‐Eun, Zacco, Elsa, Pastore, Annalisa, Sunde, Margaret, Clarke, David J., Downey, Patrick, Kunath, Tilo, Horrocks, Mathew H.

“…Protein misfolding and aggregation into oligomeric and fibrillar structures is a common feature of many neurogenerative disorders. Single‐molecule techniques…”
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Gold-Catalyzed Waste-Free Generation and Reaction of Azomethine Ylides: Internal Redox/Dipolar Cycloaddition Cascade by Yeom, Hyun-Suk, Lee, Ji-Eun, Shin, Seunghoon

“…High‐octane synthesis: Azomethine ylides can be generated from an internal redox reaction of a nitrone‐tethered alkyne under electrophilic metal catalysis (see…”
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KMT2D regulates specific programs in heart development via histone H3 lysine 4 di-methylation by Ang, Siang-Yun, Uebersohn, Alec, Spencer, C Ian, Huang, Yu, Lee, Ji-Eun, Ge, Kai, Bruneau, Benoit G

“…KMT2D, which encodes a histone H3K4 methyltransferase, has been implicated in human congenital heart disease in the context of Kabuki syndrome. However, its…”
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Multi-dimensional super-resolution imaging enables surface hydrophobicity mapping by Bongiovanni, Marie N., Godet, Julien, Horrocks, Mathew H., Tosatto, Laura, Carr, Alexander R., Wirthensohn, David C., Ranasinghe, Rohan T., Lee, Ji-Eun, Ponjavic, Aleks, Fritz, Joelle V., Dobson, Christopher M., Klenerman, David, Lee, Steven F.

“…Super-resolution microscopy allows biological systems to be studied at the nanoscale, but has been restricted to providing only positional information. Here,…”
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