Search Results - "Lee, E Y P"

miR-495 is upregulated by E12 E47 in breast cancer stem cells, and promotes oncogenesis and hypoxia resistance via downregulation of E-cadherin and REDD1 by Hwang-Verslues, W W, Chang, P-H, Wei, P-C, Yang, C-Y, Huang, C-K, Kuo, W-H, Shew, J-Y, Chang, K-J, Lee, E Y-H P, Lee, W-H

“…MicroRNAs (miRNAs) are involved in tumorigenecity by regulating specific oncogenes and tumor suppressor genes, and their roles in breast cancer stem cells…”
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Regulation of cell lineage specification by the retinoblastoma tumor suppressor by Skapek, S X, Pan, Y-R, Lee, E Y-H P

“…Early studies of the retinoblastoma gene (RB) have uncovered its critical role as a regulator of the G(1)/S cell cycle phase progression. Surprisingly, genetic…”
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Novel small molecules disrupting Hec1/Nek2 interaction ablate tumor progression by triggering Nek2 degradation through a death-trap mechanism by Hu, C-M, Zhu, J, Guo, X E, Chen, W, Qiu, X-L, Ngo, B, Chien, R, Wang, Y V, Tsai, C Y, Wu, G, Kim, Y, Lopez, R, Chamberlin, A R, Lee, EY-HP, Lee, W-H

“…Hec1 (highly expressed in cancer 1) or Nek2 (NIMA-related kinase 2) is often overexpressed in cancers with poor prognosis. Both are critical mitotic…”
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The emerging roles of functional imaging in ovarian cancer with peritoneal carcinomatosis by An, H., Lee, E.Y.P., Chiu, K., Chang, C.

“…This article reviews the emerging roles of functional imaging in the assessment of peritoneal carcinomatosis in ovarian cancer, focusing on the use of…”
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Contrast induced nephropathy in vascular surgery by Wong, G.T.C., Lee, E.Y.P., Irwin, M.G.

“…Contrast induced nephropathy (CIN) is traditionally associated with outpatient imaging studies. More recently, patients afflicted with vascular pathologies are…”
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Isolated popliteus tendon avulsion in skeletally immature patients by Wheeler, L.D, Lee, E.Y.P, Lloyd, D.C.F

“…Four cases of isolated popliteus tendon avulsion in skeletally immature patients that presented to our institution over an 11 month period are reviewed. All…”
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Functional tumour volume and peritoneal carcinomatosis to identify suitable candidates for cytoreductive surgery in ovarian carcinoma: abridged secondary publication by Lee, E Y P, Hui, E S K, Ngan, H Y S

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Functional link between ataxia-telangiectasia and Nijmegen breakage syndrome gene products by Lee, Eva Y.-H. P, Zhao, Song, Weng, Yi-Chinn, Yuan, Shyng-Shiou F, Lin, Yi-Tzu, Hsu, Hao-Chi, Lin, Suh-Chin J, Gerbino, Elvira, Song, Mei-hua, Zdzienicka, Malgorzata Z, Gatti, Richard A, Shay, Jerry W, Ziv, Yael, Shiloh, Yosef

“…Ataxia-telangiectasia (A-T) and Nijmegen breakage syndrome (NBS) are recessive genetic disorders with susceptibility to cancer and similar cellular phenotypes…”
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BRCA2 is required for ionizing radiation-induced assembly of Rad51 complex in vivo by YUAN, S.-S. F, LEE, S.-Y, GANG CHEN, MEIHUA SONG, TOMLINSON, G. E, LEE, E. Y.-H. P

“…Mutations in BRCA1 and BRCA2 account for the majority of familial breast cancers. Cells with mutated BRCA1 or BRCA2 are hypersensitive to ionizing radiation…”
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The retinoblastoma gene product regulates progression through the G1 phase of the cell cycle by Goodrich, D W, Wang, N P, Qian, Y W, Lee, E Y, Lee, W H

“…The RB gene product is a nuclear phosphoprotein that undergoes cell cycle-dependent changes in its phosphorylation status. To test whether RB regulates cell…”
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Current Strategies and Recent Advances in Gynaecological Oncology Imaging by Wong, EMF, Lai, AYT, Lee, EYP

“…Imaging is now a crucial tool in the management of gynaecological cancers to optimise clinical outcomes. This review provides an update on the current role and…”
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Oncogenes and tumor suppressor genes by Lee, Eva Y H P, Muller, William J

“…Breast cancer progression involves multiple genetic events, which can activate dominant-acting oncogenes and disrupt the function of specific tumor suppressor…”
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Mice deficient in both p53 and Rb develop tumors primarily of endocrine origin by HARVEY, M, VOGEL, H, LEE, E. Y.-H. P, BRADLEY, A, DONEHOWER, L. A

“…To examine whether a cooperative role exists between inherited Rb and p53 deficiency in tumorigenesis, crosses were made between p53- and Rb-deficient mice and…”
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The retinoblastoma susceptibility gene encodes a nuclear phosphoprotein associated with DNA binding activity by Lee, Wen-Hwa, Shew, Jin-Yuh, Hong, Frank D, Sery, Theodore W, Donoso, Larry A, Young, Lih-Jiuan, Bookstein, Robert, Lee, Eva Y.-H. P

“…The human gene (RB) that determines susceptibility to hereditary retinoblastoma has been identified recently by molecular genetic techniques. Previous results…”
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Structure of the Human Retinoblastoma Gene by Hong, Frank D., Huang, Huei-Jen S., To, Hoang, Young, Lih-Jiuan S., Oro, Anthony, Bookstein, Robert, Eva Y.-H. P. Lee, Lee, Wen-Hwa

“…Complete inactivation of the human retinoblastoma gene (RB) is believed to be an essential step in tumorigenesis of several different cancers. To provide a…”
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Retinoblastoma gene deficiency has mitogenic but not tumorigenic effects on erythropoiesis by HU, N, GULLEY, M. L, KUNG, J. T, LEE, E. Y.-H. P

“…The retinoblastoma protein (Rb), an important ubiquitous cell cycle regulator, was initially identified as the retinoblastoma tumor suppressor. To further…”
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Human Retinoblastoma Susceptibility Gene: Genomic Organization and Analysis of Heterozygous Intragenic Deletion Mutants by Bookstein, Robert, Eva Y.-H. P. Lee, To, Hoang, Young, Lih-Jiuan, Sery, Theodore W., Hayes, Robert C., Friedmann, Theodore, Lee, Wen-Hwa

“…A gene in chromosome region 13q14 has been identified as the human retinoblastoma susceptibility (RB) gene on the basis of altered gene expression found in…”
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Molecular Cloning of the Human Esterase D Gene, a Genetic Marker of Retinoblastoma by Eva Y.-H. P. Lee, Lee, Wen-Hwa

“…Retinoblastoma, the most common intraocular tumor, represents one of the prototypes of inheritable cancers. To elucidate the mechanisms that give rise to this…”
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Susceptibility to tumors induced in mice by ethylnitrosourea is independent of retinoblastoma gene dosage by RILEY, D. J, CHEN-CHING LAI, CHI-YAO CHANG, JONES, D, LEE, E. Y.-H. P, WEN-HWA LEE

“…The retinoblastoma gene (RB) is a classical tumor suppressor. Several studies have shown that RB dosage is important in determining biological effects. To…”
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The Divergent Robo Family Protein Rig-1/Robo3 Is a Negative Regulator of Slit Responsiveness Required for Midline Crossing by Commissural Axons by Sabatier, Christelle, Plump, Andrew S, Le Ma, Brose, Katja, Tamada, Atsushi, Murakami, Fujio, Lee, Eva Y.-H.P, Tessier-Lavigne, Marc

“…Commissural axons in vertebrates and insects are initially attracted to the nervous system midline, but once they reach this intermediate target they undergo a…”
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