Search Results - "Lee, Donghoon M."
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Dynamin regulates the dynamics and mechanical strength of the actin cytoskeleton as a multifilament actin-bundling protein
Published in Nature cell biology (01-06-2020)“…The dynamin GTPase is known to bundle actin filaments, but the underlying molecular mechanism and physiological relevance remain unclear. Our genetic analyses…”
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2
Projective light-sheet microscopy with flexible parameter selection
Published in Nature communications (29-03-2024)“…Projection imaging accelerates volumetric interrogation in fluorescence microscopy, but for multi-cellular samples, the resulting images may lack contrast, as…”
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3
An Arf-GEF Regulates Antagonism between Endocytosis and the Cytoskeleton for Drosophila Blastoderm Development
Published in Current biology (04-11-2013)“…Actin cytoskeletal networks push and pull the plasma membrane (PM) to control cell structure and behavior. Endocytosis also regulates the PM and can be…”
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4
Polarized E-cadherin endocytosis directs actomyosin remodeling during embryonic wound repair
Published in The Journal of cell biology (31-08-2015)“…Embryonic epithelia have a remarkable ability to rapidly repair wounds. A supracellular actomyosin cable around the wound coordinates cellular movements and…”
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5
An Actomyosin-Arf-GEF Negative Feedback Loop for Tissue Elongation under Stress
Published in Current biology (07-08-2017)“…In response to a pulling force, a material can elongate, hold fast, or fracture. During animal development, multi-cellular contraction of one region often…”
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6
Spectrin is a mechanoresponsive protein shaping fusogenic synapse architecture during myoblast fusion
Published in Nature cell biology (01-06-2018)“…Spectrin is a membrane skeletal protein best known for its structural role in maintaining cell shape and protecting cells from mechanical damage. Here, we…”
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PH Domain-Arf G Protein Interactions Localize the Arf-GEF Steppke for Cleavage Furrow Regulation in Drosophila
Published in PloS one (10-11-2015)“…The recruitment of GDP/GTP exchange factors (GEFs) to specific subcellular sites dictates where they activate small G proteins for the regulation of various…”
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Drosophila Myoblast Fusion: Invasion and Resistance for the Ultimate Union
Published in Annual review of genetics (03-12-2019)“…Cell-cell fusion is indispensable for creating life and building syncytial tissues and organs. Ever since the discovery of cell-cell fusion, how cells join…”
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9
A modifier screen for Bazooka/PAR-3 interacting genes in the Drosophila embryo epithelium
Published in PloS one (01-04-2010)“…The development and homeostasis of multicellular organisms depends on sheets of epithelial cells. Bazooka (Baz; PAR-3) localizes to the apical circumference of…”
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10
Germ Cell Segregation from the Drosophila Soma Is Controlled by an Inhibitory Threshold Set by the Arf-GEF Steppke
Published in Genetics (Austin) (01-07-2015)“…Germline cells segregate from the soma to maintain their totipotency, but the cellular mechanisms of this segregation are unclear. The Drosophila melanogaster…”
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11
Stepping stone: a cytohesin adaptor for membrane cytoskeleton restraint in the syncytial Drosophila embryo
Published in Molecular biology of the cell (15-02-2015)“…Cytohesin Arf-GEFs are conserved plasma membrane regulators. The sole Drosophila cytohesin, Steppke, restrains Rho1-dependent membrane cytoskeleton activity at…”
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12
Coordinating the cytoskeleton and endocytosis for regulated plasma membrane growth in the early Drosophila embryo
Published in Bioarchitecture (11-03-2014)“…Plasma membrane organization is under the control of cytoskeletal networks and endocytic mechanisms, and a growing literature is showing how closely these…”
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13
Theoretical investigation of the conformational intricacies and thermodynamic functions of noradrenaline
Published in Canadian journal of chemistry (01-08-2011)“…Noradrenaline is a neurotransmitter that is involved in various psychological processes. In the neurotransmission process, noradrenaline binds to an adrenergic…”
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PH Domain-Arf G Protein Interactions Localize the Arf-GEF Steppke for Cleavage Furrow Regulation in Drosophila: e0142562
Published in PloS one (01-11-2015)“…The recruitment of GDP/GTP exchange factors (GEFs) to specific subcellular sites dictates where they activate small G proteins for the regulation of various…”
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15
The Arf-GEF Steppke controls cell division in the early Drosophila embryo
Published 01-01-2015“…The early Drosophila embryo forms somatic and germ cells by cell division from a syncytium. This process requires dynamic plasma membrane remodelling shaped by…”
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Dissertation -
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A case of rectus sheath hematoma caused by yoga exercise
Published in The American journal of emergency medicine (01-09-2009)“…Rectus sheath hematoma is a relatively rare condition but a significant cause of acute abdominal pain. The acute abdominal pain associated with rectus sheath…”
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The relationship between alcohol consumption and injury in ED trauma patients
Published in The American journal of emergency medicine (01-10-2009)“…Abstract Background Alcohol-related injuries are significantly more serious than non–alcohol-related injuries. However, there have been few data on the…”
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