Search Results - "Lee, David Y.W."

Identification of hepatoprotective flavonolignans from silymarin by Polyak, Stephen J, Morishima, Chihiro, Lohmann, Volker, Pal, Sampa, Lee, David Y.W, Liu, Yanze, Graf, Tyler N, Oberlies, Nicholas H

“…Silymarin, also known as milk thistle extract, inhibits hepatitis C virus (HCV) infection and also displays antioxidant, anti-inflammatory, and…”
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A UPLC-MS/MS method for simultaneous quantitation of three monoterpene glycosides and four alkaloids in rat plasma: application to a comparative pharmacokinetic study of Huo Luo Xiao Ling Dan and single herb extract by Ai, Yu, Wu, Yun, Wang, Fenrong, Ma, Wen, Bian, Qiaoxia, Lee, David Y.-W., Dai, Ronghua

“…The objective of this study was to develop a sensitive and reliable ultra performance liquid chromatography‐tandem mass spectrometry (UPLC‐MS/MS) method for…”
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Ultra-high performance liquid chromatography with tandem mass spectrometry method for the simultaneous quantitation of five phthalides in rat plasma: Application to a comparative pharmacokinetic study of Huo Luo Xiao Ling Dan and herb-pair extract by Ma, Wen, Wang, Weihui, Peng, Yan, Bian, Qiaoxia, Wang, Nannan, Lee, David Y.-W., Dai, Ronghua

“…A fast, sensitive, and reliable ultra‐high performance liquid chromatography with tandem mass spectrometry method has been developed and validated for the…”
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Pharmacokinetics, tissue distribution, and excretion studies of l‐isocorypalmine using ultra high performance liquid chromatography with tandem mass spectrometry by Wang, Weihui, Liu, Jing, Zhao, Xiaoning, Peng, Yan, Wang, Nannan, Lee, David Y. W., Dai, Ronghua

“…l‐Isocorypalmine is a newly identified metabolite of l‐tetrahydropalmatine with a unique dual pharmacological profile as a partial dopamine receptor 1 agonist…”
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Systematic chemical profiling of a multicomponent Chinese herbal formula Huo Luo Xiao Ling Dan by ultra high performance liquid chromatography coupled with electrospray ionization quadrupoletime-of-flight mass spectrometry by Wang, Fenrong, Ai, Yu, Wu, Yun, Ma, Wen, Bian, Qiaoxia, Lee, David Y.-W., Dai, Ronghua

“…Huo Luo Xiao Ling Dan, a Chinese herbal formula consisting of 11 different herbs, has been used in folk medicine for the treatment of arthritis and other…”
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Making a bigger deal of the smaller words: Function words and other key items in research writing by Chinese learners by Lee, David Y.W., Chen, Sylvia Xiao

“…In many mainland Chinese universities, undergraduate students specializing in English language and applied linguistics are required to write a dissertation, in…”
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Synthesis and biological evaluation of C-2 halogenated analogs of salvinorin A by Lee, David Y.W., Yang, Lu, Xu, Wei, Deng, Gang, Guo, Lin, Liu-Chen, Lee-Yuan

“…We have carried out the synthesis and biological evaluation of C-2 halogenation analogs of salvinorin A. KOPR binding and functional studies reveal β isomer in…”
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Thermal degradation products derived from the smoke of Salvia divinorum leaves by Ma, Zhongze, Deng, Gang, Dai, Ronghua, Xu, Wei, Liu-Chen, Lee-Yuan, Lee, David Y.W.

“…Smoking of Salvia divinorum leaves is the most common method for its psychotropic effects. Eleven thermal degradation products, including a new neoclerodane…”
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Total synthesis of puerarin, an isoflavone C-glycoside by Lee, David Y.W., Zhang, Wu-Yan, Karnati, Vishnu Vardhan R.

“…We completed the first total synthesis of puerarin ( 1 ), an isoflavone C-glycoside. The key intermediate, β- d-glucopyranosyl-2,6-dimethoxybenzene ( 9 ), was…”
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A comparison of oral and intravenous pimonidazole in canine tumors using intravenous CCI-103F as a control hypoxia marker by Kleiter, Miriam M, Thrall, Donald E, Malarkey, David E, Ji, Xiaoshen, Lee, David Y W, Chou, Shu-Chuan, Raleigh, James A

“…Pimonidazole HCl is widely used in immunohistochemical analyses of hypoxia in normal and malignant tissues. The present study investigates oral administration…”
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Traditional Chinese herbal medicine at the forefront battle against COVID-19: Clinical experience and scientific basis by Lee, David Y.W., Li, Qing Y., Liu, Jing, Efferth, Thomas

“…Throughout the 5000-year history of China, more than 300 epidemics were recorded. Traditional Chinese herbal medicine (TCM) has been used effectively to combat…”
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Role of Levo-tetrahydropalmatine and its metabolites for management of chronic pain and opioid use disorders by Liu, Jing, Dai, Ronghua, Damiescu, Roxana, Efferth, Thomas, Lee, David Y.W.

“…•L-THP and its metabolites have dual pharmacological properties, acting as D1 agonists and D2 antagonists.•Preclinical data using various relapse models show…”
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Combining the wisdoms of traditional medicine with cutting-edge science and technology at the forefront of medical sciences by Efferth, Thomas, Xu, An-Long, Lee, David Y.W.

“…A central topic is to bring traditional medicine to a new horizon by integrating the latest advances in genomic, metabolomic, and system biological approaches,…”
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Can Essential Oils Provide an Alternative Adjuvant Therapy for COVID-19 Infections and Pain Management at the Same Time? by Damiescu, Roxana, Lee, David Y. W, Efferth, Thomas

“…The active compounds from essential oils have been an important asset in treating different diseases for many centuries. Nowadays, there are various available…”
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GENRES, REGISTERS, TEXT TYPES, DOMAINS, AND STYLES: CLARIFYING THE CONCEPTS AND NAVIGATING A PATH THROUGH THE BNC JUNGLE by Lee, David Y W

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Health(care) in the Crisis: Reflections in Science and Society on Opioid Addiction by Damiescu, Roxana, Banerjee, Mita, Lee, David Y W, Paul, Norbert W, Efferth, Thomas

“…Opioid abuse and misuse have led to an epidemic which is currently spreading worldwide. Since the number of opioid overdoses is still increasing, it is…”
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Defining Core Vocabulary and Tracking Its Distribution across Spoken and Written Genres: Evidence of a Gradience of Variation from the British National Corpus by Lee, David Y. W.

“…Seven different working definitions of the notion of core vocabulary are critically examined, & a practical amalgam is adopted to clarify intuitions regarding…”
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Natural medicine HLXL targets multiple pathways of amyloid-mediated neuroinflammation and immune response in treating alzheimer's disease by Liang, Yingxia, Lee, David Y.W., Zhen, Sherri, Sun, Haoqi, Zhu, Biyue, Liu, Jing, Lei, Dan, Lin, Chih-Chung Jerry, Zhang, Siyi, Jacques, Nicholas A., Quinti, Luisa, Ran, Chongzhao, Wang, Changning, Griciuc, Ana, Choi, Se Hoon, Dai, Rong Hua, Efferth, Thomas, Tanzi, Rudolph E., Zhang, Can

“…Based on the complex pathology of AD, a single chemical approach may not be sufficient to deal simultaneously with multiple pathways of amyloid-tau…”
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Inhibition of T-Cell Inflammatory Cytokines, Hepatocyte NF-κB Signaling, and HCV Infection by Standardized Silymarin by Polyak, Stephen J, Morishima, Chihiro, Shuhart, Margaret C, Wang, Chia C, Liu, Yanze, Lee, David Y.–W

“…Background & Aims: Chronic hepatitis C is a serious global medical problem necessitating effective treatment. Because standard of care with pegylated…”
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Asymmetric total synthesis of tetrahydroprotoberberine derivatives and evaluation of their binding affinities at dopamine receptors by Lee, David Y.W., Liu, Jing, Zhang, Shuzhen, Huang, Peng, Liu-Chen, Lee-Yuan

“…[Display omitted] Cocaine addiction remains a serious challenge for clinical and medical research because there is no effective pharmacological treatment…”
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