Search Results - "Lee, David Y. W."

Can Essential Oils Provide an Alternative Adjuvant Therapy for COVID-19 Infections and Pain Management at the Same Time? by Damiescu, Roxana, Lee, David Y. W, Efferth, Thomas

“…The active compounds from essential oils have been an important asset in treating different diseases for many centuries. Nowadays, there are various available…”
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Identification of hepatoprotective flavonolignans from silymarin by Polyak, Stephen J, Morishima, Chihiro, Lohmann, Volker, Pal, Sampa, Lee, David Y.W, Liu, Yanze, Graf, Tyler N, Oberlies, Nicholas H

“…Silymarin, also known as milk thistle extract, inhibits hepatitis C virus (HCV) infection and also displays antioxidant, anti-inflammatory, and…”
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A single dose of kudzu extract reduces alcohol consumption in a binge drinking paradigm by Penetar, David M, Toto, Lindsay H, Lee, David Y.-W, Lukas, Scott E

“…Highlights • Isoflavone containing compounds have traditionally been studied to alleviate alcohol problems. • An extract of the kudzu root is shown to…”
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Silymarin Inhibits In Vitro T-Cell Proliferation and Cytokine Production in Hepatitis C Virus Infection by Morishima, Chihiro, Shuhart, Margaret C, Wang, Chia C, Paschal, Denise M, Apodaca, Minjun C, Liu, Yanze, Sloan, Derek D, Graf, Tyler N, Oberlies, Nicholas H, Lee, David Y.–W, Jerome, Keith R, Polyak, Stephen J

“…Background & Aims Silymarin, an extract from the seeds of the milk thistle plant Silybum marianum , has been used for centuries for the treatment of chronic…”
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l -Isocorypalmine reduces behavioral sensitization and rewarding effects of cocaine in mice by acting on dopamine receptors by Xu, Wei, Wang, Yujun, Ma, Zhongze, Chiu, Yi-Ting, Huang, Peng, Rasakham, Khampaseuth, Unterwald, Ellen, Lee, David Y.-W, Liu-Chen, Lee-Yuan

“…Abstract Background We previously reported isolation of l -isocorypalmine ( l -ICP), a mono-demethylated analog of l -tetrahydropalmatine ( l -THP), from the…”
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Ultra-high performance liquid chromatography with tandem mass spectrometry method for the simultaneous quantitation of five phthalides in rat plasma: Application to a comparative pharmacokinetic study of Huo Luo Xiao Ling Dan and herb-pair extract by Ma, Wen, Wang, Weihui, Peng, Yan, Bian, Qiaoxia, Wang, Nannan, Lee, David Y.-W., Dai, Ronghua

“…A fast, sensitive, and reliable ultra‐high performance liquid chromatography with tandem mass spectrometry method has been developed and validated for the…”
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A UPLC-MS/MS method for simultaneous quantitation of three monoterpene glycosides and four alkaloids in rat plasma: application to a comparative pharmacokinetic study of Huo Luo Xiao Ling Dan and single herb extract by Ai, Yu, Wu, Yun, Wang, Fenrong, Ma, Wen, Bian, Qiaoxia, Lee, David Y.-W., Dai, Ronghua

“…The objective of this study was to develop a sensitive and reliable ultra performance liquid chromatography‐tandem mass spectrometry (UPLC‐MS/MS) method for…”
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A standardized kudzu extract (NPI-031) reduces alcohol consumption in nontreatment-seeking male heavy drinkers by Lukas, Scott E., Penetar, David, Su, Zhaohui, Geaghan, Thomas, Maywalt, Melissa, Tracy, Michael, Rodolico, John, Palmer, Christopher, Ma, Zhongze, Lee, David Y.-W.

“…Objective We previously demonstrated that short-term treatment with a standardized kudzu extract (NPI-031) reduced alcohol drinking by men and women in a…”
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The isoflavone puerarin reduces alcohol intake in heavy drinkers: A pilot study by Penetar, David M, Toto, Lindsay H, Farmer, Stacey L, Lee, David Y.-W, Ma, Zhongze, Liu, Yanze, Lukas, Scott E

“…Abstract Background Isoflavone compounds naturally occurring in the root of the kudzu plant have been used historically to treat alcohol-related problems. A…”
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Silymarin Protects Against Acute Ethanol-Induced Hepatotoxicity in Mice by Song, Zhenyuan, Deaciuc, Ion, Song, Ming, Lee, David Y.-W., Liu, Yanze, Ji, Xiaosheng, McClain, Craig

“…Background: Accumulated evidence has demonstrated that both oxidative stress and abnormal cytokine production, especially tumor necrosis factor‐α (TNF), play…”
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Pharmacokinetic comparison of five tanshinones in normal and arthritic rats after oral administration of Huo Luo Xiao Ling Dan or its single herb extract by UPLC-MS/MS by Ma, Wen, Peng, Yan, Wang, Weihui, Bian, Qiaoxia, Wang, Nannan, Lee, David Y.-W., Dai, Ronghua

“…A fast, sensitive and reliable ultra performance liquid chromatography–tandem mass spectrometry (UPLC‐MS/MS) method has been developed and validated for…”
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Molecular structure and stereochemistry of silybin A, silybin B, isosilybin A, and isosilybin B, isolated from Silybum marianum (milk thistle) by Lee, D.Y.W, Liu, Y

“…Two pairs of diastereoisomeric flavonolignans, silybin A, silybin B, isosilybin A, and isosilybin B, were successfully separated from Silybum marianum by…”
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Metabolites identification of Huo Luo Xiao Ling Dan in rat urine by UPLC coupled with electrospray ionization time-of-flight mass spectrometry by Wang, Fenrong, Wu, Yun, Ai, Yu, Bian, Qiaoxia, Ma, Wen, Lee, David Y.-W., Dai, Ronghua

“…Huo Luo Xiao Ling Dan (HLXLD), a Chinese herbal formula, is used in folk medicine for the treatment of arthritis and other chronic inflammatory diseases…”
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Comparative pharmacokinetic study of two boswellic acids in normal and arthritic rat plasma after oral administration of Boswellia serrata extract or Huo Luo Xiao Ling Dan by LC-MS by Wang, Hui, Zhang, Chenning, Wu, Yun, Ai, Yu, Lee, David Y.-W., Dai, Ronghua

“…ABSTRACT Huo Luo Xiao Ling Dan (HLXLD), a Chinese herbal formula composed of 11 different herbs, has been used traditionally for the treatment of arthritis and…”
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Simultaneous determination of four secoiridoid and iridoid glycosides in rat plasma by ultra performance liquid chromatography-tandem mass spectrometry and its application to a comparative pharmacokinetic study by Wu, Yun, Ai, Yu, Wang, Fenrong, Ma, Wen, Bian, Qiaoxia, Lee, David Y.-W., Dai, Ronghua

“…A simple, reliable and rapid ultra‐performance liquid chromatography–tandem mass spectrometry method was developed and validated for the simultaneous…”
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Palmitic Acid Is a Novel CD4 Fusion Inhibitor That Blocks HIV Entry and Infection by Lee, David Y-W, Lin, Xudong, Paskaleva, Elena E, Liu, Yanze, Puttamadappa, Shadakshara S, Thornber, Carol, Drake, James R, Habulin, Maja, Shekhtman, Alexander, Canki, Mario

“…The high rate of HIV-1 mutation and the frequent sexual transmission highlight the need for novel therapeutic modalities with broad activity against both CXCR4…”
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An Extract of the Chinese Herbal Root Kudzu Reduces Alcohol Drinking by Heavy Drinkers in a Naturalistic Setting by Lukas, Scott E., Penetar, David, Berko, Jeff, Vicens, Luke, Palmer, Christopher, Mallya, Gopinath, Macklin, Eric A., Lee, David Y.-W.

“…Background: Of the available medications for treating alcohol‐related problems, none are universally effective, and all have side effects that may limit their…”
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Inhibition of T-Cell Inflammatory Cytokines, Hepatocyte NF-κB Signaling, and HCV Infection by Standardized Silymarin by Polyak, Stephen J, Morishima, Chihiro, Shuhart, Margaret C, Wang, Chia C, Liu, Yanze, Lee, David Y.–W

“…Background & Aims: Chronic hepatitis C is a serious global medical problem necessitating effective treatment. Because standard of care with pegylated…”
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Suppression of Ongoing Experimental Arthritis by a Chinese Herbal Formula (Huo-Luo-Xiao-Ling Dan) Involves Changes in Antigen-Induced Immunological and Biochemical Mediators of Inflammation by Yang, Ying-Hua, Rajaiah, Rajesh, Lee, David Y.-W., Ma, Zhongze, Yu, Hua, Fong, Harry H. S., Lao, Lixing, Berman, Brian, Moudgil, Kamal D.

“…Rheumatoid arthritis (RA) is one of the major autoimmune diseases of global prevalence. The use of the anti-inflammatory drugs for the treatment of RA is…”
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Simultaneous determination of seven coumarins by UPLC–MS/MS: Application to a comparative pharmacokinetic study in normal and arthritic rats after oral administration of Huo Luo Xiao Ling Dan or single-herb extract by Wu, Yun, Wang, Fenrong, Ai, Yu, Ma, Wen, Bian, Qiaoxia, Lee, David Y.-W., Dai, Ronghua

“…•A UPLC–MS/MS method was developed for pharmacokinetic study of Huo Luo Xiao Ling Dan.•Simultaneous determination of seven coumarins.•The lower limits of…”
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