Search Results - "Lee, Daniel"
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1
Chromatin mechanics dictates subdiffusion and coarsening dynamics of embedded condensates
Published in Nature physics (01-04-2021)“…DNA is organized into chromatin, a complex polymeric material that stores information and controls gene expression. An emerging mechanism for biological…”
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2
Competing Protein-RNA Interaction Networks Control Multiphase Intracellular Organization
Published in Cell (16-04-2020)“…Liquid-liquid phase separation (LLPS) mediates formation of membraneless condensates such as those associated with RNA processing, but the rules that dictate…”
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3
Graphene electro-optic modulator with 30 GHz bandwidth
Published in Nature photonics (01-08-2015)“…Scientists have realized a graphene electro-optic modulator operating with a 30 GHz bandwidth and with a state-of-the-art modulation efficiency of 1.5 dB V −1…”
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4
Separability and geometry of object manifolds in deep neural networks
Published in Nature communications (06-02-2020)“…Stimuli are represented in the brain by the collective population responses of sensory neurons, and an object presented under varying conditions gives rise to…”
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5
Mechanical Frustration of Phase Separation in the Cell Nucleus by Chromatin
Published in Physical review letters (25-06-2021)“…Liquid-liquid phase separation is a fundamental mechanism underlying subcellular organization. Motivated by the striking observation that optogenetically…”
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Liquid Nuclear Condensates Mechanically Sense and Restructure the Genome
Published in Cell (29-11-2018)“…Phase transitions involving biomolecular liquids are a fundamental mechanism underlying intracellular organization. In the cell nucleus, liquid-liquid phase…”
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7
'Delegating sovereignty': Chapter 5: Governing sovereignty: Negotiating French absolutism in Europe
Published in European Journal of International Law (01-08-2021)Get full text
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8
A versatile approach for the synthesis of degradable polymers via controlled ring-opening metathesis copolymerization
Published in Nature chemistry (01-01-2022)“…Norbornene derivatives (NBEs) are common monomers for living ring-opening metathesis polymerization and yield polymers with low dispersities and diverse…”
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9
Classification and Geometry of General Perceptual Manifolds
Published in Physical review. X (01-07-2018)“…Perceptual manifolds arise when a neural population responds to an ensemble of sensory signals associated with different physical features (e.g., orientation,…”
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10
HIV: how to manage dyslipidaemia in HIV
Published in Drugs in Context (01-03-2022)“…Dyslipidaemia is a common metabolic condition occurring in people with HIV (PWH), whether treated or untreated with antiretroviral therapy (ART). As people…”
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11
Learning Optimal Resource Allocations in Wireless Systems
Published in IEEE transactions on signal processing (15-05-2019)“…This paper considers the design of optimal resource allocation policies in wireless communication systems, which are generically modeled as a functional…”
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12
Access to Sudden Hearing Loss Care at Urgent Care Centers
Published in The Laryngoscope (01-12-2024)“…Objectives To compare patient access to urgent care centers (UCCs) with a diagnosis of sudden hearing loss based on insurance. Methods One hundred twenty‐five…”
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13
Current concepts in the diagnosis and management of cytokine release syndrome
Published in Blood (10-07-2014)“…As immune-based therapies for cancer become potent, more effective, and more widely available, optimal management of their unique toxicities becomes…”
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14
Size distributions of intracellular condensates reflect competition between coalescence and nucleation
Published in Nature physics (2023)“…Phase separation of biomolecules into condensates has emerged as a mechanism for intracellular organization and affects many intracellular processes, including…”
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15
The Clinician-Administered PTSD Scale for DSM-5 (CAPS-5): Development and Initial Psychometric Evaluation in Military Veterans
Published in Psychological assessment (01-03-2018)“…The Clinician-Administered PTSD Scale (CAPS) is an extensively validated and widely used structured diagnostic interview for posttraumatic stress disorder…”
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16
Making the Grade (But Not Disclosing It): How Withholding Grades Affects Student Behavior and Employment
Published in Management science (01-04-2024)“…We study the effects of grade nondisclosure (GND) policies implemented within master of business administration (MBA) programs at highly ranked business…”
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17
Population coding of affect across stimuli, modalities and individuals
Published in Nature neuroscience (01-08-2014)“…The authors found human neuroimaging evidence that entire valence spectrum is represented as a collective pattern in regional neural activity, with…”
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Reliable and Clinically Significant Change in the Clinician-Administered PTSD Scale for DSM-5 and PTSD Checklist for DSM-5 Among Male Veterans
Published in Psychological assessment (01-02-2022)“…We calculated the reliable change index (RCI) and clinically significant change (CSC) values for two widely used measures of posttraumatic stress disorder…”
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19
The role of microglia in amyloid clearance from the AD brain
Published in Journal of Neural Transmission (01-08-2010)“…Alzheimer’s disease (AD), the most prominent cause of senile dementia, is clinically characterized by the extracellular deposition of β-amyloid (Aβ) and the…”
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Elevated TREM2 Gene Dosage Reprograms Microglia Responsivity and Ameliorates Pathological Phenotypes in Alzheimer’s Disease Models
Published in Neuron (Cambridge, Mass.) (07-03-2018)“…Variants of TREM2 are associated with Alzheimer’s disease (AD). To study whether increasing TREM2 gene dosage could modify the disease pathogenesis, we…”
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