Search Results - "Lee, Chun G."

Chitin recognition via chitotriosidase promotes pathologic type-2 helper T cell responses to cryptococcal infection by Wiesner, Darin L, Specht, Charles A, Lee, Chrono K, Smith, Kyle D, Mukaremera, Liliane, Lee, S Thera, Lee, Chun G, Elias, Jack A, Nielsen, Judith N, Boulware, David R, Bohjanen, Paul R, Jenkins, Marc K, Levitz, Stuart M, Nielsen, Kirsten

“…Pulmonary mycoses are often associated with type-2 helper T (Th2) cell responses. However, mechanisms of Th2 cell accumulation are multifactorial and…”
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TLR-2 and IL-17A in Chitin-Induced Macrophage Activation and Acute Inflammation by Da Silva, Carla A, Hartl, Dominik, Liu, Wei, Lee, Chun G, Elias, Jack A

“…Chitin is a ubiquitous polysaccharide in fungi, insects, and parasites. To test the hypothesis that chitin is an important immune modulator, we characterized…”
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Chitin Is a Size-Dependent Regulator of Macrophage TNF and IL-10 Production by Da Silva, Carla A, Chalouni, Cecile, Williams, Adam, Hartl, Dominik, Lee, Chun G, Elias, Jack A

“…Chitin is a ubiquitous polysaccharide in fungi, insects, and parasites. We hypothesized that chitin is a size-dependent regulator of innate immunity. To test…”
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Hyperoxia causes angiopoietin 2-mediated acute lung injury and necrotic cell death by Elias, Jack A, Bhandari, Vineet, Choo-Wing, Rayman, Lee, Chun G, Zhu, Zhou, Nedrelow, Jonathan H, Chupp, Geoffrey L, Zhang, Xucher, Matthay, Michael A, Ware, Lorraine B, Homer, Robert J, Lee, Patty J, Geick, Anke, de Fougerolles, Antonin R

“…The angiogenic growth factor angiopoietin 2 (Ang2) destabilizes blood vessels, enhances vascular leak and induces vascular regression and endothelial cell…”
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Chitinase 3-like 1 synergistically activates IL6-mediated STAT3 phosphorylation in intestinal epithelial cells in murine models of infectious colitis by Tran, Hoa T, Lee, In-Ah, Low, Daren, Kamba, Alan, Mizoguchi, Atsushi, Shi, Hai N, Lee, Chun G, Elias, Jack A, Mizoguchi, Emiko

“…Chitinase 3-like 1 (CHI3L1) is an inducible molecule on intestinal epithelial cells during the development of inflammatory bowel disease. To investigate the…”
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Antifibrotic role of vascular endothelial growth factor in pulmonary fibrosis by Murray, Lynne A, Habiel, David M, Hohmann, Miriam, Camelo, Ana, Shang, Huilan, Zhou, Yang, Coelho, Ana Lucia, Peng, Xueyan, Gulati, Mridu, Crestani, Bruno, Sleeman, Matthew A, Mustelin, Tomas, Moore, Meagan W, Ryu, Changwan, Osafo-Addo, Awo D, Elias, Jack A, Lee, Chun G, Hu, Buqu, Herazo-Maya, Jose D, Knight, Darryl A, Hogaboam, Cory M, Herzog, Erica L

“…The chronic progressive decline in lung function observed in idiopathic pulmonary fibrosis (IPF) appears to result from persistent nonresolving injury to the…”
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Essential Role of Nitric Oxide in VEGF-Induced, Asthma-like Angiogenic, Inflammatory, Mucus, and Physiologic Responses in the Lung by Bhandari, Vineet, Choo-Wing, Rayman, Chapoval, Svetlana P., Lee, Chun G., Tang, C., Kim, Y. K., Ma, Bing, Baluk, Peter, Lin, Michelle I., McDonald, Donald M., Homer, Robert J., Sessa, William C., Elias, Jack A.

“…VEGF, nitric oxide (NO), inflammation, and vascular- and extravascular remodeling coexist in asthma and other disorders. In these responses, VEGF regulates…”
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Acidic Mammalian Chitinase Is Secreted via an ADAM17/Epidermal Growth Factor Receptor-dependent Pathway and Stimulates Chemokine Production by Pulmonary Epithelial Cells by Hartl, Dominik, He, Chuan Hua, Koller, Barbara, Da Silva, Carla A., Homer, Robert, Lee, Chun G., Elias, Jack A.

“…Acidic mammalian chitinase (AMCase) is expressed in an exaggerated fashion in epithelial cells at sites of pulmonary T helper cell type 2 inflammation and…”
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Vascular endothelial growth factor enhances macrophage clearance of apoptotic cells by Kearns, Mark T, Dalal, Samay, Horstmann, Sarah A, Richens, Tiffany R, Tanaka, Takeshi, Doe, Jenna M, Boe, Darren M, Voelkel, Norbert F, Taraseviciene-Stewart, Laimute, Janssen, William J, Lee, Chun G, Elias, Jack A, Bratton, Donna, Tuder, Rubin M, Henson, Peter M, Vandivier, R William

“…Efficient clearance of apoptotic cells from the lung by alveolar macrophages is important for the maintenance of tissue structure and function. Lung tissue…”
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Fatty Acid Binding Protein 4 Regulates VEGF-Induced Airway Angiogenesis and Inflammation in a Transgenic Mouse Model by Ghelfi, Elisa, Yu, Chen-Wei, Elmasri, Harun, Terwelp, Matthew, Lee, Chun G, Bhandari, Vineet, Comhair, Suzy A, Erzurum, Serpil C, Hotamisligil, Gökhan S, Elias, Jack A, Cataltepe, Sule

“…Neovascularization of the airways occurs in several inflammatory lung diseases, including asthma. Vascular endothelial growth factor (VEGF) plays an important…”
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Cloning and Characterization of a Cell Surface Receptor for Xenotropic and Polytropic Murine Leukemia Viruses by Tailor, Chetankumar S., Nouri, Ali, Lee, Chun G., Kozak, Christine, Kabat, David

“…Xenotropic and polytropic murine leukemia viruses (X-MLVs and P-MLVs) cross-interfere to various extents in non-mouse species and in wild Asian mice,…”
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Chitinase 3-like-1 regulates both visceral fat accumulation and asthma-like Th2 inflammation by Ahangari, Farida, Sood, Akshay, Ma, Bing, Takyar, Seyedtaghi, Schuyler, Mark, Qualls, Clifford, Dela Cruz, Charles S, Chupp, Geoffrey L, Lee, Chun G, Elias, Jack A

“…Obesity, especially truncal obesity, is a risk factor for asthma incidence, prevalence, and severity. Chitinase 3-like-1 (Chi3l1) is an evolutionarily…”
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Fatty acid binding protein 4 regulates VEGF-induced airway angiogenesis and inflammation in a transgenic mouse model: implications for asthma by Ghelfi, Elisa, Yu, Chen-Wei, Elmasri, Harun, Terwelp, Matthew, Lee, Chun G, Bhandari, Vineet, Comhair, Suzy A, Erzurum, Serpil C, Hotamisligil, Gökhan S, Elias, Jack A, Cataltepe, Sule

“…Neovascularization of the airways occurs in several inflammatory lung diseases, including asthma. Vascular endothelial growth factor (VEGF) plays an important…”
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Developmental Regulation of NO-Mediated VEGF-Induced Effects in the Lung by Bhandari, Vineet, Choo-Wing, Rayman, Lee, Chun G, Yusuf, Kamran, Nedrelow, Jonathan H, Ambalavanan, Namasivayam, Malkus, Herbert, Homer, Robert J, Elias, Jack A

“…Vascular endothelial growth factor (VEGF) is known to have a pivotal role in lung development and in a variety of pathologic conditions in the adult lung. Our…”
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Adenosine mediates IL-13-induced inflammation and remodeling in the lung and interacts in an IL-13-adenosine amplification pathway by Blackburn, Michael R, Lee, Chun G, Young, Hays W J, Zhu, Zhou, Chunn, Janci L, Kang, Min Jong, Banerjee, Suman K, Elias, Jack A

“…IL-13 is an important mediator of inflammation and remodeling. We hypothesized that adenosine accumulation, alterations in adenosine receptors, and…”
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Genetic Control of a Mouse Serum Lipoprotein Factor That Inactivates Murine Leukemia Viruses: Evaluation of Apolipoprotein F as a Candidate by Wu, Tiyun, Lee, Chun G, Buckler-White, Alicia, Kozak, Christine A

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Partially adenosine deaminase-deficient mice develop pulmonary fibrosis in association with adenosine elevations by Chunn, Janci L, Mohsenin, Amir, Young, Hays W J, Lee, Chun G, Elias, Jack A, Kellems, Rodney E, Blackburn, Michael R

“…Adenosine, a signaling nucleoside, exhibits tissue-protective and tissue-destructive effects. Adenosine levels in tissues are controlled in part by the enzyme…”
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Novel biomarkers in asthma: chemokines and chitinase-like proteins by Hartl, Dominik, Lee, Chun G, Da Silva, Carla A, Chupp, Geoffrey L, Elias, Jack A

“…PURPOSE OF REVIEWAllergic asthma is a frequent lung disease in Western civilizations and is characterized by airway inflammation and tissue remodeling. Without…”
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Tetracycline-controlled transcriptional regulation systems: advances and application in transgenic animal modeling by Zhu, Zhou, Zheng, Tao, Lee, Chun G, Homer, Robert J, Elias, Jack A

“…Since the first tetracycline-controlled transcriptional activation system was designed nearly a decade ago, new variants, modifications, and improvements have…”
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Role of 5-Lipoxygenase in IL-13-Induced Pulmonary Inflammation and Remodeling by Shim, Yun M, Zhu, Zhou, Zheng, Tao, Lee, Chun G, Homer, Robert J, Ma, Bing, Elias, Jack A

“…Exaggerated levels of IL-13 and leukotriene (LT) pathway activation frequently coexist at sites of Th2 inflammation and in tissue fibrotic responses. However,…”
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