Search Results - "Lee, Christina E"

Posttranslational Modifications Mediate the Structural Diversity of Tauopathy Strains by Arakhamia, Tamta, Lee, Christina E., Carlomagno, Yari, Kumar, Mukesh, Duong, Duc M., Wesseling, Hendrik, Kundinger, Sean R., Wang, Kevin, Williams, Dewight, DeTure, Michael, Dickson, Dennis W., Cook, Casey N., Seyfried, Nicholas T., Petrucelli, Leonard, Steen, Judith A., Fitzpatrick, Anthony W.P.

“…Tau aggregation into insoluble filaments is the defining pathological hallmark of tauopathies. However, it is not known what controls the formation and…”
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Targeted Lysosomal Degradation of Secreted and Cell Surface Proteins through the LRP‑1 Pathway by Loppinet, Elise, Besser, Harrison A., Lee, Christina E., Zhang, Wei, Cui, Bianxiao, Khosla, Chaitan

“…Protein dysregulation has been characterized as the cause of pathogenesis in many different diseases. For proteins lacking easily druggable pockets or…”
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Probing mechanical forces in curvature-sensitive cell adhesions by Lee, Christina E., Zhang, Wei, Cui, Bianxiao

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Curved adhesions mediate cell attachment to soft matrix fibres in three dimensions by Zhang, Wei, Lu, Chih-Hao, Nakamoto, Melissa L., Tsai, Ching-Ting, Roy, Anish R., Lee, Christina E., Yang, Yang, Jahed, Zeinab, Li, Xiao, Cui, Bianxiao

“…Integrin-mediated focal adhesions are the primary architectures that transmit forces between the extracellular matrix (ECM) and the actin cytoskeleton…”
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Single piconewton forces regulate dissociation of the Latrophilin-3 gain domain by Zhong, Brian L., Lee, Christina E., Vachharajani, Vipul T., Sudhof, Thomas C., Dunn, Alexander R.

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Piconewton Forces Mediate GAIN Domain Dissociation of the Latrophilin‑3 Adhesion GPCR by Zhong, Brian L., Lee, Christina E., Vachharajani, Vipul T., Bauer, Magnus S., Südhof, Thomas C., Dunn, Alexander R.

“…Latrophilins are adhesion G-protein coupled receptors (aGPCRs) that control excitatory synapse formation. Most aGPCRs, including latrophilins, are…”
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Posttranslational Modifications Mediate the Structural Diversity of Tauopathy Strains by Arakhamia, Tamta, Lee, Christina E., Carlomagno, Yari, Kumar, Mukesh, Duong, Duc M., Wesseling, Hendrik, Kundinger, Sean R., Wang, Kevin, Williams, Dewight, DeTure, Michael, Dickson, Dennis W., Cook, Casey N., Seyfried, Nicholas T., Petrucelli, Leonard, Steen, Judith A., Fitzpatrick, Anthony W.P.

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Potent, Low-Molecular-Weight Non-Peptide Inhibitors of Malarial Aspartyl Protease Plasmepsin II by Haque, Tasir S, Skillman, A. Geoffrey, Lee, Christina E, Habashita, Hiromu, Gluzman, Ilya Y, Ewing, Todd J. A, Goldberg, Daniel E, Kuntz, Irwin D, Ellman, Jonathan A

“…A number of single-digit nanomolar, low-molecular-weight plasmepsin II aspartyl protease inhibitors have been identified using combinatorial chemistry and…”
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General Solid-Phase Synthesis Approach To Prepare Mechanism-Based Aspartyl Protease Inhibitor Libraries. Identification of Potent Cathepsin D Inhibitors by Lee, Christina E, Kick, Ellen K, Ellman, Jonathan A

“…A general method has been developed for the expedient solid-phase synthesis of aspartyl protease inhibitors that do not incorporate any amino acids. The…”
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(Silox) 3Nb(η 2-N,C-4-picoline) as a source of (silox) 3Nb: structure of [(silox) 3Nb] 2(μ-η 2,η 2-C 6H 6) (silox= tBu 3SiO) by Veige, Adam S., Kleckley, Troy S., Chamberlin, Rebecca M., Neithamer, David R., Lee, Christina E., Wolczanski, Peter T., Lobkovsky, Emil B., Glassey, Wingfied V.

“…Electrochemical and chemical reductions of (silox) 3NbCl 2 ( 1, −1.42 V versus Ag/Ag +) and (silox) 3TaCl 2 ( 2, −2.18 V) generated [(silox) 3NbCl 2] − ( 1 −)…”
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Approximating the Stationary Probability of a Single State in a Markov chain by Lee, Christina E, Ozdaglar, Asuman, Shah, Devavrat

“…In this paper, we present a novel iterative Monte Carlo method for approximating the stationary probability of a single state of a positive recurrent Markov…”
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Scanty journalism: The reporting of non-election public opinion polls by Canadian newspapers by Lee, Christina E

“…Canadian daily newspapers are frequently publishing non-election public opinion poll results that are unsophisticated, unfair, and do not disclose important…”
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