Search Results - "Lee, Chieh A."
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Aryl Hydrocarbon Receptor Agonist VAF347 Impedes Retinal Pathogenesis in Diabetic Mice
Published in International journal of molecular sciences (21-04-2021)“…Diabetic retinopathy is the leading cause of blindness in the working-age population worldwide. Although the cause of diabetic retinopathy is multifactorial,…”
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Anti-IL17A Halts the Onset of Diabetic Retinopathy in Type I and II Diabetic Mice
Published in International journal of molecular sciences (10-01-2023)“…There are ~463 million diabetics worldwide, and more than half have diabetic retinopathy. Yet, treatments are still lacking for non-proliferative diabetic…”
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3
IL-17A Enhances Retinal Neovascularization
Published in International journal of molecular sciences (16-01-2023)“…Retinal neovascularization occurs in proliferative diabetic retinopathy, neovascular glaucoma, and age-related macular degeneration. This type of retinal…”
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4
RORγt Inhibitor-SR1001 Halts Retinal Inflammation, Capillary Degeneration, and the Progression of Diabetic Retinopathy
Published in International journal of molecular sciences (17-05-2020)“…Diabetic retinopathy is a diabetes-mediated retinal microvascular disease that is the leading cause of blindness in the working-age population worldwide…”
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Retinal Inflammation, Oxidative Stress, and Vascular Impairment Is Ablated in Diabetic Mice Receiving XMD8-92 Treatment
Published in Frontiers in pharmacology (11-08-2021)“…The global number of diabetics continues to rise annually. As diabetes progresses, almost all of Type I and more than half of Type II diabetics develop…”
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Inhibition of CD40-TRAF6-dependent inflammatory activity halts the onset of diabetic retinopathy in streptozotocin-diabetic mice
Published in Nutrition & diabetes (30-10-2022)“…Diabetes initiates inflammation that can impair the retinal vasculature, and lead to diabetic retinopathy; one of the leading causes of blindness. Inflammatory…”
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Diabetes-mediated IL-17A enhances retinal inflammation, oxidative stress, and vascular permeability
Published in Cellular immunology (01-07-2019)“…•Th17 cells and IL-17-producing neutrophils adhere to diabetic retinal vasculature.•Muller glia, photoreceptors, and retinal endothelial cells constitutively…”
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Diabetes induces IL-17A-Act1-FADD-dependent retinal endothelial cell death and capillary degeneration
Published in Journal of diabetes and its complications (01-09-2019)“…Diabetes leads to progressive complications such as diabetic retinopathy, which is the leading cause of blindness within the working-age population worldwide…”
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Aortic valve replacement in the elderly. Risk factors and long-term results
Published in Annals of surgery (01-06-1997)“…The current study was undertaken to determine long-term results of aortic valve replacement (AVR) in the elderly, to ascertain predictors of poor outcome, and…”
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