Search Results - "Lee, Cheryl Q. E."
-
1
Coding and non-coding roles of MOCCI (C15ORF48) coordinate to regulate host inflammation and immunity
Published in Nature communications (09-04-2021)“…Mito-SEPs are small open reading frame-encoded peptides that localize to the mitochondria to regulate metabolism. Motivated by an intriguing negative…”
Get full text
Journal Article -
2
Inhibition of Phosphoinositide‐3‐Kinase Signaling Promotes the Stem Cell State of Trophoblast
Published in Stem cells (Dayton, Ohio) (01-10-2019)“…Trophoblast stem cells (TSCs) are a heterogeneous cell population despite the presence of fibroblast growth factor (FGF) and transforming growth factor β…”
Get full text
Journal Article -
3
Integrin α2 marks a niche of trophoblast progenitor cells in first trimester human placenta
Published in Development (Cambridge) (16-04-2018)“…During pregnancy the trophoblast cells of the placenta are the only fetal cells in direct contact with maternal blood and decidua. Their functions include…”
Get full text
Journal Article -
4
A high-resolution map of human RNA translation
Published in Molecular cell (04-08-2022)“…Translated small open reading frames (smORFs) can have important regulatory roles and encode microproteins, yet their genome-wide identification has been…”
Get full text
Journal Article -
5
Viral proteases activate the CARD8 inflammasome in the human cardiovascular system
Published in The Journal of experimental medicine (03-10-2022)“…Nucleotide-binding oligomerization domain (NBD), leucine-rich repeat (LRR) containing protein family (NLRs) are intracellular pattern recognition receptors…”
Get full text
Journal Article -
6
What Is Trophoblast? A Combination of Criteria Define Human First-Trimester Trophoblast
Published in Stem cell reports (09-02-2016)“…Controversy surrounds reports describing the derivation of human trophoblast cells from placentas and embryonic stem cells (ESC), partly due to the difficulty…”
Get full text
Journal Article -
7
Mast cell activation in lungs during SARS-CoV-2 infection associated with lung pathology and severe COVID-19
Published in The Journal of clinical investigation (01-10-2023)“…Lung inflammation is a hallmark of Coronavirus disease 2019 (COVID-19) in patients who are severely ill, and the pathophysiology of disease is thought to be…”
Get full text
Journal Article -
8
Esrrb function is required for proper primordial germ cell development in presomite stage mouse embryos
Published in Developmental biology (15-11-2019)“…Estrogen related receptor beta (Esrrb) is an orphan nuclear receptor that is required for self-renewal and pluripotency in mouse embryonic stem (ES) cells…”
Get full text
Journal Article -
9
A niche of trophoblast progenitor cells identified by integrin α2 is present in first trimester human placentas
Published in Development (Cambridge) (01-01-2018)“…During pregnancy the trophoblast cells of the placenta are the only fetal cells in direct contact with maternal blood and decidua. Their functions include…”
Get full text
Journal Article