Search Results - "Lee, Casey S"
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Thymus-derived B cell clones persist in the circulation after thymectomy in myasthenia gravis
Published in Proceedings of the National Academy of Sciences - PNAS (01-12-2020)“…Myasthenia gravis (MG) is a neuromuscular, autoimmune disease caused by autoantibodies that target postsynaptic proteins, primarily the acetylcholine receptor…”
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Early B cell tolerance defects in neuromyelitis optica favour anti-AQP4 autoantibody production
Published in Brain (London, England : 1878) (01-06-2019)“…Neuromyelitis optica spectrum disorders (NMOSD) constitute rare autoimmune disorders of the CNS that are primarily characterized by severe inflammation of the…”
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Fate induction in CD8 CAR T cells through asymmetric cell division
Published in Nature (London) (19-09-2024)“…Early expansion and long-term persistence predict efficacy of chimeric antigen receptor T cells (CARTs) 1 – 7 , but mechanisms governing effector versus memory…”
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Circulating plasmablasts are elevated and produce pathogenic anti‐endothelial cell autoantibodies in idiopathic pulmonary arterial hypertension
Published in European journal of immunology (01-05-2018)“…Idiopathic pulmonary arterial hypertension (IPAH) is a devastating pulmonary vascular disease in which autoimmune and inflammatory phenomena are implicated. B…”
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Compromised fidelity of B‐cell tolerance checkpoints in AChR and MuSK myasthenia gravis
Published in Annals of clinical and translational neurology (01-06-2016)“…Objective Myasthenia gravis (MG) is an autoimmune condition in which neurotransmission is impaired by binding of autoantibodies to acetylcholine receptors…”
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