Search Results - "Lee, C Soon"

Multigene panel next generation sequencing in metastatic colorectal cancer in an Australian population by Nindra, Udit, Pal, Abhijit, Lea, Vivienne, Lim, Stephanie Hui-Su, Wilkinson, Kate, Asghari, Ray, Roberts, Tara L, Becker, Therese M, Farzin, Mahtab, Rutland, Tristan, Lee, Mark, MacKenzie, Scott, Ng, Weng, Wang, Bin, Lee, C. Soon, Chua, Wei

“…Background Next generation sequencing (NGS) is increasingly used in standard clinical practice to identify patients with potentially actionable mutations…”
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A rat model of ataxia-telangiectasia: evidence for a neurodegenerative phenotype by Quek, Hazel, Luff, John, Cheung, KaGeen, Kozlov, Sergei, Gatei, Magtouf, Lee, C Soon, Bellingham, Mark C, Noakes, Peter G, Lim, Yi Chieh, Barnett, Nigel L, Dingwall, Steven, Wolvetang, Ernst, Mashimo, Tomoji, Roberts, Tara L, Lavin, Martin F

“…Ataxia-telangiectasia (A-T), an autosomal recessive disease caused by mutations in the ATM gene is characterised by cerebellar atrophy and progressive…”
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Human papillomavirus, smoking status and outcomes in tonsillar squamous cell carcinoma by Hong, Angela M., Martin, Andrew, Chatfield, Mark, Jones, Deanna, Zhang, Mei, Armstrong, Bruce, Lee, C. Soon, Harnett, Gerald, Milross, Christopher, Clark, Jonathan, Elliott, Michael, Smee, Robert, Corry, June, Liu, Chen, Porceddu, Sandro, Rees, Guy, Rose, Barbara

“…It is now clear that the two separate entitles of tonsillar cancer, HPV induced and non‐HPV induced (smoking induced), have significantly different presenting…”
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Molecular patterns in salivary duct carcinoma identify prognostic subgroups by Mueller, Simon A., Gauthier, Marie-Emilie A., Blackburn, James, Grady, John P., Kraitsek, Spiridoula, Hajdu, Elektra, Dettmer, Matthias S., Dahlstrom, Jane E., Lee, C. Soon, Luk, Peter P., Yu, Bing, Giger, Roland, Kummerfeld, Sarah, Clark, Jonathan R., Gupta, Ruta, Cowley, Mark J.

“…Salivary duct carcinoma (SDCa) is a rare cancer with high rate of metastases and poor survival despite aggressive multimodality treatment. This study analyzes…”
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Breast ductal carcinoma in situ carry mutational driver events representative of invasive breast cancer by Pang, Jia-Min B, Savas, Peter, Fellowes, Andrew P, Mir Arnau, Gisela, Kader, Tanjina, Vedururu, Ravikiran, Hewitt, Chelsee, Takano, Elena A, Byrne, David J, Choong, David YH, Millar, Ewan KA, Lee, C Soon, O'Toole, Sandra A, Lakhani, Sunil R, Cummings, Margaret C, Mann, G Bruce, Campbell, Ian G, Dobrovic, Alexander, Loi, Sherene, Gorringe, Kylie L, Fox, Stephen B

“…The spectrum of genomic alterations in ductal carcinoma in situ (DCIS) is relatively unexplored, but is likely to provide useful insights into its biology, its…”
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Rats with a missense mutation in Atm display neuroinflammation and neurodegeneration subsequent to accumulation of cytosolic DNA following unrepaired DNA damage by Quek, Hazel, Luff, John, Cheung, KaGeen, Kozlov, Sergei, Gatei, Magtouf, Lee, C. Soon, Bellingham, Mark C., Noakes, Peter G., Lim, Yi Chieh, Barnett, Nigel L., Dingwall, Steven, Wolvetang, Ernst, Mashimo, Tomoji, Roberts, Tara L., Lavin, Martin F.

“…Decreased ATM expression leads to accumulation of cytosolic DNA and neuroinflammation. Mutations in the ataxia‐telangiectasia (A‐T)‐mutated (ATM) gene give…”
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International study group on rectal cancer regression grading: interobserver variability with commonly used regression grading systems by Chetty, Runjan, MB BCh, FRCPath, DPhil, Gill, Pelvender, MB ChB, Govender, Dhirendra, MB ChB, FRCPath, PhD, Bateman, Adrian, FRCPath, Chang, Hee Jin, MD, Deshpande, Vikram, MD, Driman, David, MD, Gomez, Marisa, MD, Greywoode, Godman, FRCPath, Jaynes, Eleanor, FRCPath, Lee, C. Soon, FRCPA, PhD, Locketz, Michael, FCPath, Rowsell, Corwyn, FRCPC, Rullier, Anne, MD, Serra, Stefano, MD, Shepherd, Neil, FRCPath, Szentgyorgyi, Eva, FRCPC, Vajpeyi, Rajkumar, FRCPC, Wang, Lai Mun, FRCPath, Bateman, Andrew, MD

“…Summary The aim of this study was to ascertain the level of concordance among gastrointestinal pathologists for regression grading in rectal cancers treated…”
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The role of NDRG1 in the pathology and potential treatment of human cancers by Bae, Dong-Hun, Jansson, Patric J, Huang, Michael L, Kovacevic, Zaklina, Kalinowski, Danuta, Lee, C Soon, Sahni, Sumit, Richardson, Des R

“…N-myc downstream regulated gene 1 (NDRG1) has been well characterised to act as a metastatic suppressor in a number of human cancers. It has also been…”
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HPV Status of Oropharyngeal Cancer by Combination HPV DNA/p16 Testing: Biological Relevance of Discordant Results by Hong, Angela, Jones, Deanna, Chatfield, Mark, Soon Lee, C., Zhang, Mei, Clark, Jonathan, Elliott, Michael, Harnett, Gerald, Milross, Christopher, Rose, Barbara

“…Background and Purpose Human papillomavirus (HPV) causes up to 70 % of oropharyngeal cancers (OSCC). HPV positive OSCC has a more favorable outcome, thus HPV…”
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Relationships between epidermal growth factor receptor expression and human papillomavirus status as markers of prognosis in oropharyngeal cancer by Hong, Angela, Dobbins, Timothy, Lee, C. Soon, Jones, Deanna, Jackson, Elise, Clark, Jonathan, Armstrong, Bruce, Harnett, Gerald, Milross, Christopher, O’Brien, Christopher, Rose, Barbara

“…Abstract Purpose This study examines the prognostic significance of epidermal growth factor receptor (EGFR) expression in relation to human papillomavirus…”
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MRE11 and ATM Expression Levels Predict Rectal Cancer Survival and Their Association with Radiotherapy Response by Ho, Vincent, Chung, Liping, Revoltar, Maxine, Lim, Stephanie H, Tut, Thein-Ga, Abubakar, Askar, Henderson, Chris J, Chua, Wei, Ng, Weng, Lee, Mark, De Souza, Paul, Morgan, Matthew, Lee, C Soon, Shin, Joo-Shik

“…Aberrant expression of DNA repair proteins is associated with poor survival in cancer patients. We investigated the combined expression of MRE11 and ATM as a…”
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Expression of S100A2 Calcium-Binding Protein Predicts Response to Pancreatectomy for Pancreatic Cancer by Biankin, Andrew V, Kench, James G, Colvin, Emily K, Segara, Davendra, Scarlett, Christopher J, Nguyen, Nam Q, Chang, David K, Morey, Adrienne L, Lee, C.–Soon, Pinese, Mark, Kuo, Samuel C.L, Susanto, Johana M, Cosman, Peter H, Lindeman, Geoffrey J, Visvader, Jane E, Nguyen, Tuan V, Merrett, Neil D, Warusavitarne, Janindra, Musgrove, Elizabeth A, Henshall, Susan M, Sutherland, Robert L

“…Background & Aims Current methods of preoperative staging and predicting outcome following pancreatectomy for pancreatic cancer (PC) are inadequate. We…”
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Squamous cell carcinoma of the oropharynx in Australian males induced by human papillomavirus vaccine targets by Hong, Angela M, Grulich, Andrew E, Jones, Deanna, Lee, C. Soon, Garland, Suzanne M, Dobbins, Timothy A, Clark, Jonathan R, Harnett, Gerald B, Milross, Christopher G, O’Brien, Christopher J, Rose, Barbara R

“…Abstract This study provides Australian data on the incidence of human papillomavirus (HPV)-related oropharyngeal cancer to aid the debate on extending the HPV…”
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Ki67 Expression has Prognostic Significance in Relation to Human Papillomavirus Status in Oropharyngeal Squamous Cell Carcinoma by Liu, Jia, Zhang, Mei, Rose, Barbara, Veillard, Anne-Sophie, Jones, Deanna, Zhang, Xiaoying, Soon Lee, C., Milross, Chris, Hong, Angela

“…Background Human papillomavirus (HPV) is the major predictor of outcome in oropharyngeal squamous cell carcinoma (OSCC) but the disease is heterogeneous and…”
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Low AZGP1 expression predicts for recurrence in margin-positive, localized prostate cancer by Yip, Po Yee, Kench, James G., Rasiah, Krishan K., Benito, Ruth Pe, Lee, C.-Soon, Stricker, Phillip D., Henshall, Susan M., Sutherland, Robert L., Horvath, Lisa G.

“…BACKGROUND Men with positive margins after radical prostatectomy (RP) for localized prostate cancer (PC) have a 40–50% biochemical relapse rate at 5 years…”
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Development of Two-Dimensional Classroom Discourse Analysis Tool (CDAT): scientific reasoning and dialog patterns in the secondary science classes by Lee, Soon C., Irving, Karen E.

“…Background In a science classroom, students do not simply learn scientific ways of doing, knowing, and reasoning unless they find ways of appropriating…”
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Expression of glucose-regulated stress protein GRP78 is related to progression of melanoma by Zhuang, Liquing, Scolyer, Richard A, Lee, C Soon, McCarthy, Stanley W, Cooper, Wendy A, Zhang, Xu D, Thompson, John F, Hersey, Peter

“…Aims:  Glucose‐regulated protein 78 (GRP78) is a protein translated in response to endoplasmic reticulum (ER) stress that has been implicated in the…”
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Prognostic Significance of Vascular Endothelial Growth Factor in Squamous Cell Carcinomas of the Tonsil in Relation to Human Papillomavirus Status and Epidermal Growth Factor Receptor by Fei, Jimin, Hong, Angela, Dobbins, Timothy A., Jones, Deanna, Soon Lee, C., Loo, Christine, Al-Ghamdi, Mohammad, Harnett, Gerald B., Clark, Jonathan, O’Brien, Christopher J., Rose, Barbara

“…Background Angiogenesis markers, vascular endothelial growth factor (VEGF) and microvessel density (MVD) have been associated with prognosis in squamous cell…”
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Prognostic Impact of TP53 Mutations and Tumor Mutational Load in Colorectal Cancer by Ho, Vincent, Chung, Liping, Lim, Stephanie H., Ma, Yafeng, Wang, Bin, Lea, Vivienne, Abubakar, Askar, Ng, Weng, Lee, Mark, Roberts, Tara L., Chua, Wei, Lee, C. Soon

“…The DNA damage response (DDR) is critical for maintaining genome stability, and abnormal DDR—resulting from mutations in DNA damage-sensing and repair…”
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The significance of the Wnt pathway in the pathology of human cancers by Karim, Rooshdiya Z., Tse, Gary M.K., Putti, Thomas C., Scolyer, Richard A., Soon Lee, C.

“…The wingless-type (Wnt) signalling transduction pathway is essentially a network of a number of separate but interacting pathways. Specific Wnt ligands bind to…”
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