Search Results - "Lee, Beom Suk"
-
1
Doxorubicin/gold-loaded core/shell nanoparticles for combination therapy to treat cancer through the enhanced tumor targeting
Published in Journal of controlled release (28-04-2016)“…A combination therapy consisting of radiotherapy and chemotherapy is performed using the core/shell nanoparticles (NPs) containing gold NPs and doxorubicin…”
Get full text
Journal Article -
2
Inhibitory Role of TRIP-Br1/XIAP in Necroptosis under Nutrient/Serum Starvation
Published in Molecules and cells (2020)“…Currently, many available anti-cancer therapies are targeting apoptosis. However, many cancer cells have acquired resistance to apoptosis. To overcome this…”
Get full text
Journal Article -
3
Production of a thermo-tolerant κ-carrageenase via a food-grade host and anti-oxidant activity of its enzymatic hydrolysate
Published in Food chemistry (01-03-2021)“…•A new κ-carrageenase was expressed in a food-grade host.•The recombinant κ-carrageenase showed thermo-tolerant property.•Yielding a single homogeneous…”
Get full text
Journal Article -
4
Enhancing the Thermo-Stability and Anti-Biofilm Activity of Alginate Lyase by Immobilization on Low Molecular Weight Chitosan Nanoparticles
Published in International journal of molecular sciences (14-09-2019)“…Bacterial biofilm causes severe antibiotic resistance. An extracellular polymeric substance (EPS) is the main component in the bacterial biofilm. Alginate is a…”
Get full text
Journal Article -
5
Theranostic nanoparticles based on PEGylated hyaluronic acid for the diagnosis, therapy and monitoring of colon cancer
Published in Biomaterials (01-09-2012)“…Abstract Colon cancer is the second leading cause of cancer-related death in the United States. The considerable mortality from colon cancer is due to…”
Get full text
Journal Article -
6
Biochemical Characterization of a New Oligoalginate Lyase and Its Biotechnological Application in Laminaria japonica Degradation
Published in Frontiers in microbiology (10-03-2020)“…Oligoalginate lyases catalyze the degradation of alginate polymers and oligomers into monomers, a prerequisite for biotechnological utilizing alginate. In this…”
Get full text
Journal Article -
7
Tumor targeting efficiency of bare nanoparticles does not mean the efficacy of loaded anticancer drugs: Importance of radionuclide imaging for optimization of highly selective tumor targeting polymeric nanoparticles with or without drug
Published in Journal of controlled release (15-10-2010)“…The better understanding of polymeric nanoparticles as a drug delivery carrier is a decisive factor to get more efficient therapeutic response in vivo. Here,…”
Get full text
Journal Article -
8
SERTAD1 Sensitizes Breast Cancer Cells to Doxorubicin and Promotes Lysosomal Protein Biosynthesis
Published in Biomedicines (17-05-2022)“…Acquired chemoresistance of tumor cells is an unwanted consequence of cancer treatment. Overcoming chemoresistance is particularly important for efficiently…”
Get full text
Journal Article -
9
Potentiation of anti-angiogenic activity of heparin by blocking the ATIII-interacting pentasaccharide unit and increasing net anionic charge
Published in Biomaterials (01-12-2012)“…Abstract Heparin, a potent anticoagulant used for the prevention of venous thromboembolism, has been recognized as a tumor angiogenesis inhibitor. Its…”
Get full text
Journal Article -
10
Exploring the Role of TRIP-Brs in Human Breast Cancer: An Investigation of Expression, Clinicopathological Significance, and Prognosis
Published in Molecular therapy. Oncolytics (16-12-2020)“…TRIP-Brs, a group of transcription factors (TFs) that modulate several mechanisms in higher organisms. However, the novel paradigm to target TRIP-Brs in…”
Get full text
Journal Article -
11
Moderately decreased renal function negatively affects the health-related quality of life among the elderly Korean population: a population-based study
Published in Nephrology, dialysis, transplantation (01-09-2008)“…Background. The incidence of chronic kidney disease (CKD) is increasing in Korea, especially in the aged population. The health-related quality of life (HRQOL)…”
Get full text
Journal Article -
12
Output Formulation for Symmetrically Excited One-to- N Multimode Interference Coupler
Published in IEEE journal of selected topics in quantum electronics (01-01-2010)“…In this paper, we present a closed form formulation for the output signals of one-to- N multimode interference coupler under symmetric excitation. We derive…”
Get full text
Journal Article -
13
Demonstration of a Linearized Traveling Wave Y-Fed Directional Coupler Modulator Based on Electro-Optic Polymer
Published in Journal of lightwave technology (01-07-2011)“…In this paper, we demonstrate a traveling wave linear modulator for high speed analog optical link applications. A two-section Y-fed directional coupler…”
Get full text
Journal Article -
14
Blockchain Architectures for P2P Energy Trading Between Neighbors
Published in 2019 International Conference on Information and Communication Technology Convergence (ICTC) (01-10-2019)“…We consider blockchain architectures for P2P energy trading of surpluses and demands between prosumers and consumers in the neighborhood without any…”
Get full text
Conference Proceeding -
15
Induced phenotype targeted therapy: radiation-induced apoptosis-targeted chemotherapy
Published in JNCI : Journal of the National Cancer Institute (01-02-2015)“…Tumor heterogeneity and evolutionary complexity may underlie treatment failure in spite of the development of many targeted agents. We suggest a novel strategy…”
Get full text
Journal Article -
16
Electro-optic polymer infiltrated silicon photonic crystal slot waveguide modulator with 23 dB slow light enhancement
Published in Applied physics letters (30-08-2010)“…A silicon/organic hybrid modulator integrating photonic crystal (PC) waveguide, 75 nm slot, and electro-optic (EO) polymer is experimentally demonstrated. Slow…”
Get full text
Journal Article -
17
Novel Carbazole-Piperazine Hybrid Small Molecule Induces Apoptosis by Targeting BCL-2 and Inhibits Tumor Progression in Lung Adenocarcinoma in Vitro and Xenograft Mice Model
Published in Cancers (25-08-2019)“…Lung cancer is a type of deadly cancer and a leading cause of cancer associated death worldwide. BCL-2 protein is considered as an imperative target for the…”
Get full text
Journal Article -
18
Synergistic anti-tumor effects of bevacizumab and tumor targeted polymerized VEGF siRNA nanoparticles
Published in Biochemical and biophysical research communications (15-07-2017)“…A variety of VEGF inhibitors have been reported to treat cancers by suppressing tumor angiogenesis. Bevacizumab, a monoclonal VEGF antibody, was the first FDA…”
Get full text
Journal Article -
19
Glycol Chitosan/Heparin Immobilized Iron Oxide Nanoparticles with a Tumor-Targeting Characteristic for Magnetic Resonance Imaging
Published in Biomacromolecules (13-06-2011)“…We described the preparation of the glycol chitosan/heparin immobilized iron oxide nanoparticles (composite NPs) as a magnetic resonance imaging agent with a…”
Get full text
Journal Article -
20
High dynamic range electric field sensor for electromagnetic pulse detection
Published in Optics express (29-08-2011)“…We design a high dynamic range electric field sensor based on domain inverted electro-optic (E-O) polymer Y-fed directional coupler for electromagnetic wave…”
Get full text
Journal Article