Search Results - "Lee, Andy J"

Effect of Blood on Synovial Joint Tissues: Potential Role of Ferroptosis by Nicholson, Howard J., Sakhrani, Neeraj, Rogot, James, Lee, Andy J., Ojediran, Inioluwa G., Sharma, Ratna, Chahine, Nadeen O., Ateshian, Gerard A., Shah, Roshan P., Hung, Clark T.

“…Recurrent bleeding in the synovial joint, such as the knee, can give rise to chronic synovitis and degenerative arthritis, which are major causes of morbidity…”
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Toward Development of a Diabetic Synovium Culture Model by Sakhrani, Neeraj, Lee, Andy J, Murphy, Lance A, Kenawy, Hagar M, Visco, Christopher J, Ateshian, Gerard A, Shah, Roshan P, Hung, Clark T

“…Osteoarthritis (OA) is a degenerative joint disease characterized by articular cartilage degradation and inflammation of synovium, the specialized connective…”
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Red blood cell exposure increases chondrocyte susceptibility to oxidative stress following hemarthrosis by Lee, Andy J., Gangi, Lianna R., Zandkarimi, Fereshteh, Stockwell, Brent R., Hung, Clark T.

“…The detrimental effects of blood exposure on articular tissues are well characterized, but the individual contributions of specific whole blood components are…”
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Sustained low-dose dexamethasone delivery via a PLGA microsphere-embedded agarose implant for enhanced osteochondral repair by Stefani, Robert M., Lee, Andy J., Tan, Andrea R., Halder, Saiti S., Hu, Yizhong, Guo, X. Edward, Stoker, Aaron M., Ateshian, Gerard A., Marra, Kacey G., Cook, James L., Hung, Clark T.

“…Articular cartilage defects are a common source of joint pain and dysfunction. We hypothesized that sustained low-dose dexamethasone (DEX) delivery via an…”
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Blocking toll-like receptor 4 mitigates static loading induced pro-inflammatory expression in intervertebral disc motion segments by Kenawy, Hagar M., Marshall, Samantha L., Rogot, James, Lee, Andy J., Hung, Clark T., Chahine, Nadeen O.

“…While the anabolic effects of mechanical loading on the intervertebral disc (IVD) have been extensively studied, inflammatory responses to loading have not…”
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Hedgehog Activation for Enhanced Rotator Cuff Tendon-to-Bone Healing by Luzzi, Andrew J., Ferrer, Xavier, Fang, Fei, Golman, Mikhail, Song, Lee, Marshall, Brittany P., Lee, Andy J., Kim, Jieon J., Hung, Clark T., Thomopoulos, Stavros

“…Background: Rotator cuff repair is a common orthopaedic procedure, yet the rate of failure to heal after surgery is high. Repair site rupture is due to poor…”
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Toward defining the role of the synovium in mitigating normal articular cartilage wear and tear by Pellicore, Matthew J., Gangi, Lianna R., Murphy, Lance A., Lee, Andy J., Jacobsen, Timothy, Kenawy, Hagar M., Shah, Roshan P., Chahine, Nadeen O., Ateshian, Gerard A., Hung, Clark T.

“…Cartilage repair has been studied extensively in the context of injury and disease, but the joint’s management of regular sub-injurious damage to cartilage, or…”
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Cartilage Wear Particles Induce an Inflammatory Response Similar to Cytokines in Human Fibroblast‐Like Synoviocytes by Estell, Eben G., Silverstein, Amy M., Stefani, Robert M., Lee, Andy J., Murphy, Lance A., Shah, Roshan P., Ateshian, Gerard A., Hung, Clark T.

“…ABSTRACT The synovium plays a key role in the development of osteoarthritis, as evidenced by pathological changes to the tissue observed in both early and late…”
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The subacromial bursa modulates tendon healing after rotator cuff injury in rats by Marshall, Brittany P, Ashinsky, Beth G, Ferrer, Xavier E, Kunes, Jennifer A, Innis, Astia C, Luzzi, Andrew J, Forrester, Lynn Ann, Burt, Kevin G, Lee, Andy J, Song, Lee, Lisiewski, Lauren E, Soni, Rajesh K, Hung, Clark T, Levine, William N, Kovacevic, David, Thomopoulos, Stavros

“…Rotator cuff injuries result in more than 500,000 surgeries annually in the United States, many of which fail. These surgeries typically involve repair of the…”
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Sustained Delivery of SB-431542, a Type I Transforming Growth Factor Beta-1 Receptor Inhibitor, to Prevent Arthrofibrosis by Lee, Andy J, Mahoney, Christopher M, Cai, Charles C, Ichinose, Rika, Stefani, Robert M, Marra, Kacey G, Ateshian, Gerard A, Shah, Roshan P, Vunjak-Novakovic, Gordana, Hung, Clark T

“…Fibrosis of the knee is a common disorder resulting from an aberrant wound healing response and is characterized by extracellular matrix deposition, joint…”
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A Functional Tissue-Engineered Synovium Model to Study Osteoarthritis Progression and Treatment by Stefani, Robert M, Halder, Saiti S, Estell, Eben G, Lee, Andy J, Silverstein, Amy M, Sobczak, Evie, Chahine, Nadeen O, Ateshian, Gerard A, Shah, Roshan P, Hung, Clark T

“…The synovium envelops the diarthrodial joint and plays a key regulatory role in defining the composition of the synovial fluid through filtration and…”
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Risk factors for ischaemic stroke recurrence after hospitalisation by Lee, Andy H, Somerford, Peter J, Yau, Kelvin K W

“…Objective: To determine risk factors for ischaemic stroke recurrence among patients admitted to hospital for a first‐ever occurrence of ischaemic stroke…”
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