Search Results - "Lee, Agatha D."
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1
Genetics of Brain Fiber Architecture and Intellectual Performance
Published in The Journal of neuroscience (18-02-2009)“…The study is the first to analyze genetic and environmental factors that affect brain fiber architecture and its genetic linkage with cognitive function. We…”
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2
Genetic influences on brain asymmetry: A DTI study of 374 twins and siblings
Published in NeuroImage (Orlando, Fla.) (15-08-2010)“…Brain asymmetry, or the structural and functional specialization of each brain hemisphere, has fascinated neuroscientists for over a century. Even so, genetic…”
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3
Brain structure changes visualized in early- and late-onset blind subjects
Published in NeuroImage (Orlando, Fla.) (01-01-2010)“…We examined 3D patterns of volume differences in the brain associated with blindness, in subjects grouped according to early and late onset. Using tensor-based…”
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4
Three-Dimensional Brain Growth Abnormalities in Childhood-Onset Schizophrenia Visualized by Using Tensor-Based Morphometry
Published in Proceedings of the National Academy of Sciences - PNAS (14-10-2008)“…Earlier studies revealed progressive cortical gray matter (GM) loss in childhood-onset schizophrenia (COS) across both lateral and medial surfaces of the…”
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5
3D pattern of brain abnormalities in Williams syndrome visualized using tensor-based morphometry
Published in NeuroImage (Orlando, Fla.) (15-07-2007)“…Williams syndrome (WS) is a neurodevelopmental disorder associated with deletion of ∼ 20 contiguous genes in chromosome band 7q11.23. Individuals with WS…”
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Abnormal Cortical Complexity and Thickness Profiles Mapped in Williams Syndrome
Published in The Journal of neuroscience (20-04-2005)“…We identified and mapped an anatomically localized failure of cortical maturation in Williams syndrome (WS), a genetic condition associated with deletion of…”
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Increased local gyrification mapped in Williams syndrome
Published in NeuroImage (Orlando, Fla.) (15-10-2006)“…Applying a recently developed method to analyze gyrification with excellent spatial resolution across thousands of points across the lateral and medial…”
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8
3D pattern of brain abnormalities in Fragile X syndrome visualized using tensor-based morphometry
Published in NeuroImage (Orlando, Fla.) (01-02-2007)“…Fragile X syndrome (FraX), a genetic neurodevelopmental disorder, results in impaired cognition with particular deficits in executive function and…”
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9
Automated Extraction of the Cortical Sulci Based on a Supervised Learning Approach
Published in IEEE transactions on medical imaging (01-04-2007)“…It is important to detect and extract the major cortical sulci from brain images, but manually annotating these sulci is a time-consuming task and requires the…”
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10
Tensor-based analysis of genetic influences on brain integrity using DTI in 100 twins
Published in Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention (2009)“…Information from the full diffusion tensor (DT) was used to compute voxel-wise genetic contributions to brain fiber microstructure. First, we designed a new…”
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11
Greater Cortical Gray Matter Density in Lithium-Treated Patients with Bipolar Disorder
Published in Biological psychiatry (1969) (01-07-2007)“…Background The neurobiological underpinnings of bipolar disorder are not well understood. Previous neuroimaging findings have been inconsistent; however, new…”
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12
Developmental changes in multivariate neuroanatomical patterns that predict risk for psychosis in 22q11.2 deletion syndrome
Published in Journal of psychiatric research (01-03-2011)“…Abstract The primary objective of the current prospective study was to examine developmental patterns of voxel-by-voxel gray and white matter volumes (GMV,…”
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13
Reduced Neocortical Thickness and Complexity Mapped in Mesial Temporal Lobe Epilepsy with Hippocampal Sclerosis
Published in Cerebral cortex (New York, N.Y. 1991) (01-09-2007)“…We mapped the profile of neocortical thickness and complexity in patients with mesial temporal lobe epilepsy (MTLE) and hippocampal sclerosis. Thirty…”
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14
The contribution of genes to cortical thickness and volume
Published in Neuroreport (16-02-2011)“…We analyzed brain MRI data from 372 young adult twins toidentify cortical regions in which gray matter thickness and volume are influenced by genetics. This…”
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Increased volume of the amygdala and hippocampus in bipolar patients treated with lithium
Published in Neuroreport (22-01-2008)“…Previous structural neuroimaging studies of bipolar disorder have reported conflicting findings in limbic structures. Medication heterogeneity of patient…”
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Mapping the regional influence of genetics on brain structure variability — A Tensor-Based Morphometry study
Published in NeuroImage (Orlando, Fla.) (15-10-2009)“…Genetic and environmental factors influence brain structure and function profoundly. The search for heritable anatomical features and their influencing genes…”
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17
Statistical Properties of Jacobian Maps and the Realization of Unbiased Large-Deformation Nonlinear Image Registration
Published in IEEE transactions on medical imaging (01-06-2007)“…Maps of local tissue compression or expansion are often computed by comparing magnetic resonance imaging (MRI) scans using nonlinear image registration. The…”
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How does angular resolution affect diffusion imaging measures?
Published in NeuroImage (Orlando, Fla.) (15-01-2010)“…A key question in diffusion imaging is how many diffusion-weighted images suffice to provide adequate signal-to-noise ratio (SNR) for studies of fiber…”
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Alterations in Midline Cortical Thickness and Gyrification Patterns Mapped in Children with 22q11.2 Deletions
Published in Cerebral cortex (New York, N.Y. 1991) (01-01-2009)“…The 22q11.2 deletion syndrome (velocardiofacial/DiGeorge syndrome) is a neurogenetic condition associated with visuospatial deficits, as well as elevated rates…”
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3D Mapping of brain differences in native signing congenitally and prelingually deaf subjects
Published in Human brain mapping (01-07-2010)“…In the prelingual and congenital deaf, functional reorganization is known to occur throughout brain regions normally associated with hearing. However, the…”
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