Search Results - "Lee, A. Reum"
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Characteristics and pathogenic role of adherent-invasive Escherichia coli in inflammatory bowel disease: Potential impact on clinical outcomes
Published in PloS one (29-04-2019)“…Adherent-invasive Escherichia coli (AIEC) has been reported as associated with the pathogenesis of inflammatory bowel disease (IBD). We aimed to investigate…”
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Evaluation of gastric microbiome and metagenomic function in patients with intestinal metaplasia using 16S rRNA gene sequencing
Published in Helicobacter (Cambridge, Mass.) (01-02-2019)“…Background Despite recent advances in studies on the gastric microbiome, the role of the non‐Helicobacter pylori gastric microbiome in gastric carcinogenesis…”
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The impact of gut microbiota manipulation with antibiotics on colon tumorigenesis in a murine model
Published in PloS one (20-12-2019)“…It has been suggested that manipulation of gut microbiota using antibiotics can inhibit colitis-associated colorectal cancer (CAC) in a mouse model. We…”
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Reduced allergic lung inflammation by root extracts from two species of Peucedanum through inhibition of Th2 cell activation
Published in Journal of ethnopharmacology (20-01-2017)“…Peucedani Radix (PR), the root of Peucedanum praeruptorum Dunn (PPD) or Peucedanum decursivum (Miq.) Maxim. (PDM), has long been used in Korea to eliminate…”
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5
Lecithin nano-liposomal particle as a CRISPR/Cas9 complex delivery system for treating type 2 diabetes
Published in Journal of nanobiotechnology (29-01-2019)“…Protein-based Cas9 in vivo gene editing therapeutics have practical limitations owing to their instability and low efficacy. To overcome these obstacles and…”
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HDAC Inhibitor, CG-745, Enhances the Anti-Cancer Effect of Anti-PD-1 Immune Checkpoint Inhibitor by Modulation of the Immune Microenvironment
Published in Journal of Cancer (01-01-2020)“…Histone deacetylase inhibitors (HDACis) are well-known epigenetic regulators with therapeutic potential in various diseases. Recent studies have shown that…”
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Role of innate lymphoid cells in chronic colitis during anti-IL-17A therapy
Published in Scientific reports (15-01-2020)“…IL-17A is an important cytokine in intestinal inflammation. However, anti-IL-17A therapy does not improve clinical outcomes in patients with Crohn’s disease…”
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The immune modulatory effects of mitochondrial transplantation on cecal slurry model in rat
Published in Critical care (London, England) (07-01-2021)“…Sepsis has a high mortality rate, but no specific drug has been proven effective, prompting the development of new drugs. Immunologically, sepsis can involve…”
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Role of IL-17A in the development of colitis-associated cancer
Published in Carcinogenesis (New York) (01-04-2012)“…A close relationship between inflammation and colon cancer has been widely accepted, and interleukin (IL)-17A plays an important role in controlling colonic…”
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Network construction of gastric microbiome and organization of microbial modules associated with gastric carcinogenesis
Published in Scientific reports (27-08-2019)“…In addition to Helicobacter pylori infection, nitrosating/nitrate-reducing bacteria and type IV secretion system (T4SS) protein gene-contributing bacteria have…”
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Peucedanum japonicum extract attenuates allergic airway inflammation by inhibiting Th2 cell activation and production of pro-inflammatory mediators
Published in Journal of ethnopharmacology (30-01-2018)“…The root of Peucedanum japonicum Thunberg is traditionally used to treat coughs, colds, headache and inflammatory diseases in Korea and Japan. Its effects on…”
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Helicobacter pylori antibody and pepsinogen testing for predicting gastric microbiome abundance
Published in PloS one (04-12-2019)“…Although the high-throughput sequencing technique is useful for evaluating gastric microbiome, it is difficult to use clinically. We aimed to develop a…”
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A Fully Automated System Using A Convolutional Neural Network to Predict Renal Allograft Rejection: Extra-validation with Giga-pixel Immunostained Slides
Published in Scientific reports (26-03-2019)“…Pathologic diagnoses mainly depend on visual scoring by pathologists, a process that can be time-consuming, laborious, and susceptible to inter- and/or…”
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Theoretical study of ethyl alcohol adsorbed on a germanium (100) surface
Published in Bulletin of the Korean Chemical Society (01-12-2021)“…The chemical reaction of ethyl alcohol on a germanium surface was investigated through density functional theory analysis. The most stable product containing…”
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Role of the global gut microbial community in the development of colitis-associated cancer in a murine model
Published in Biomedicine & pharmacotherapy (01-03-2021)“…The gut microbiota has been implicated in the development of colitis-associated cancer (CAC). We investigated how the gut microbiota affects the development of…”
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Highly Ordered TiO2 Nanotube Electrodes for Efficient Quasi-Solid-State Dye-Sensitized Solar Cells
Published in Energies (Basel) (01-11-2020)“…Free-standing TiO2 nanotube (NT) electrodes have attracted much attention for application in solid- or quasi-solid-state dye-sensitized solar cells (DSSCs)…”
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Role of Fusobacteria in the serrated pathway of colorectal carcinogenesis
Published in Scientific reports (29-04-2016)“…Fusobacteria are associated with colorectal cancer (CRC) and are amplified during colorectal carcinogenesis. Compared to the adenoma-carcinoma sequence of…”
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Local Stabilization of Hypoxia-Inducible Factor-1α Controls Intestinal Inflammation via Enhanced Gut Barrier Function and Immune Regulation
Published in Frontiers in immunology (14-01-2021)“…Intestinal epithelial cells are adapted in mucosal hypoxia and hypoxia-inducible factors in these cells can fortify barrier integrity to support mucosal tissue…”
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In Vitro Preventive Effect and Mechanism of Action of Weissella cibaria CMU against Streptococcus mutans Biofilm Formation and Periodontal Pathogens
Published in Microorganisms (Basel) (01-04-2023)“…In this study, we evaluated the in vitro anti-biofilm, antibacterial, and anti-inflammatory activity of CMU (CMU), an oral probiotic, against…”
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The Effects of Mitochondrial Transplantation on Sepsis Depend on the Type of Cell from Which They Are Isolated
Published in International journal of molecular sciences (01-06-2023)“…Previously, we have shown that mitochondrial transplantation in the sepsis model has immune modulatory effects. The mitochondrial function could have different…”
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