Search Results - "Ledwon, Joanna K"

Biological Cover Mitigates Disruption of the Dermal Structure in Mechanically Expanded Skin in a Porcine Model by Ledwon, Joanna K, Applebaum, Sarah A, Progri, Bianka, Vignesh, Oveyaa, Gutowski, Kristof S, Chang, Alec B, Tepole, Adrian B, Gosain, Arun K

“…Tissue expansion is an integral procedure of the vast majority of breast reconstruction and has a significant impact on the final clinical outcomes. Therefore,…”
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The expression of fgfr3 in the zebrafish head by Ledwon, Joanna K., Turin, Sergey Y., Gosain, Arun K., Topczewska, Jolanta M.

“…Fibroblast growth factor (FGF) signaling is essential for many developmental processes and plays a pivotal role in skeletal homeostasis, regeneration and wound…”
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Pooled sample-based GWAS: a cost-effective alternative for identifying colorectal and prostate cancer risk variants in the Polish population by Gaj, Pawel, Maryan, Natalia, Hennig, Ewa E, Ledwon, Joanna K, Paziewska, Agnieszka, Majewska, Aneta, Karczmarski, Jakub, Nesteruk, Monika, Wolski, Jan, Antoniewicz, Artur A, Przytulski, Krzysztof, Rutkowski, Andrzej, Teumer, Alexander, Homuth, Georg, Starzyńska, Teresa, Regula, Jaroslaw, Ostrowski, Jerzy

“…Prostate cancer (PCa) and colorectal cancer (CRC) are the most commonly diagnosed cancers and cancer-related causes of death in Poland. To date, numerous…”
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Tissue expansion mitigates radiation-induced skin fibrosis in a porcine model by Nunez-Alvarez, Laura, Ledwon, Joanna K., Applebaum, Sarah, Progri, Bianka, Han, Tianhong, Laudo, Joel, Tac, Vahidullah, Gosain, Arun K., Tepole, Adrian Buganza

“…[Display omitted] Tissue expansion (TE) is the primary method for breast reconstruction after mastectomy. In many cases, mastectomy patients undergo radiation…”
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12-Year Trends of Orofacial Clefts in the United States: Highlighting Racial/Ethnic Differences in Prevalence of Cleft Lip and Cleft Palate by Taritsa, Iulianna C, Ledwon, Joanna K, Bajaj, Anitesh, Gosain, Arun K

“…Discrepancies in prevalence among infants with orofacial clefts are public health research priorities. Our objective was to calculate updated estimated…”
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Transcriptomic analysis reveals dynamic molecular changes in skin induced by mechanical forces secondary to tissue expansion by Ledwon, Joanna K., Kelsey, Lauren J., Vaca, Elbert E., Gosain, Arun K.

“…Tissue expansion procedures (TE) utilize mechanical forces to induce skin growth and regeneration. While the impact of quick mechanical stimulation on…”
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Modeling Tissue Expansion with Isogeometric Analysis: Skin Growth and Tissue Level Changes in the Porcine Model by Janes, Lindsay E., Ledwon, Joanna K., Vaca, Elbert E., Turin, Sergey Y., Lee, Taeksang, Tepole, Adrian B., Bae, Hanah, Gosain, Arun K.

“…Tissue expansion relies on the ability of skin to grow in response to sustained mechanical strain. This study focuses on correlation of cellular and histologic…”
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Acellular dermal matrix cover improves skin growth during tissue expansion by affecting distribution of mechanical forces by Ledwon, Joanna K., Applebaum, Sarah A., Progri, Bianka, Han, Tianhong, Vignesh, Oveyaa, Gutowski, Kristof S., Chang, Alec B., Reddy, Narainsai K., Tepole, Adrian B., Gosain, Arun K.

“…Biological cover over tissue expander prostheses has been introduced to provide soft-tissue support for tissue expanders during breast reconstruction. However,…”
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Mechanical stretching stimulates growth of the basal layer and rete ridges in the epidermis by Topczewska, Jolanta M., Ledwon, Joanna K., Vaca, Elbert E., Gosain, Arun K.

“…We have developed four experimental models of mechanical stimulation applied to the back skin using tissue expansion (TE) procedure performed on minipigs. The…”
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Langerhans cells and SFRP2/Wnt/beta‐catenin signalling control adaptation of skin epidermis to mechanical stretching by Ledwon, Joanna K., Vaca, Elbert E., Huang, Chiang C., Kelsey, Lauren J., McGrath, Jennifer L., Topczewski, Jacek, Gosain, Arun K., Topczewska, Jolanta M.

“…Skin can be mechanically stimulated to grow through a clinical procedure called tissue expansion (TE). Using a porcine TE model, we determined that expansion…”
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Drop-off in axonal regeneration along the length of a cross-face nerve graft: An experimental study in rats by Janes, Lindsay E, Kelsey, Lauren J, Sasson, Daniel C, Applebaum, Sarah, Ledwon, Joanna K, Gosain, Arun K

“…The average nerve graft length utilized in cross-face nerve grafting for reconstruction of facial nerve palsy is 20-22 cm. While the graft length is thought to…”
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The role of prospero homeobox 1 (PROX1) expression in follicular thyroid carcinoma cells by Rudzinska, Magdalena, Ledwon, Joanna K, Gawel, Damian, Sikorska, Justyna, Czarnocka, Barbara

“…The prospero homeobox 1 (Prox1) transcription factor is a key player during embryogenesis and lymphangiogenesis. Altered Prox1 expression has been found in a…”
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Improving tissue expansion protocols through computational modeling by Lee, Taeksang, Vaca, Elbert E, Ledwon, Joanna K, Bae, Hanah, Topczewska, Jolanta M, Turin, Sergey Y, Kuhl, Ellen, Gosain, Arun K, Tepole, Adrian Buganza

“…Tissue expansion is a common technique in reconstructive surgery used to grow skin in vivo for correction of large defects. Despite its popularity, there is a…”
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Digital analysis yields more reliable and accurate measures of dermal and epidermal thickness in histologically processed specimens compared to traditional methods by Turin, Sergey Y., Ledwon, Joanna K., Bae, Hanna, Buganza‐Tepole, Adrian, Topczewska, Jolanta, Gosain, Arun K.

“…Changes in the thickness of the dermis and epidermis have been described in the scenario of tissue expansion as well as inflammatory skin processes (psoriasis,…”
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SP29. Evaluation Of Mechanosensitive Markers And Their Role In Keratinocyte Proliferation In Tissue Expansion by Ledwon, Joanna K., Progri, Bianka, Applebaum, Sarah A., Vignesh, Oveyaa, Gosain, Arun K.

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Common low-penetrance risk variants associated with breast cancer in Polish women by Ledwoń, Joanna K, Hennig, Ewa E, Maryan, Natalia, Goryca, Krzysztof, Nowakowska, Dorota, Niwińska, Anna, Ostrowski, Jerzy

“…Breast cancer is the most common type of cancer and the second leading cause of cancer-death among women in Poland. The known high-risk mutations account for…”
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71. Evaluation of Axonal Regeneration Across a Long Cross-face Nerve Graft in Rats by Kelsey, Lauren J., Janes, Lindsay E., Sasson, Daniel, Ledwon, Joanna K., Gosain, Arun K.

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QS69. The Biological Role of Acellular Dermal Matrix in Improving Outcomes of Tissue Expansion When Subject to Radiation Therapy by Applebaum, Sarah A., Ledwon, Joanna K., Progri, Bianka, Gutowski, Kristof, Gosain, Arun K.

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44. The Effect of Acellular Dermal Matrix on Skin Growth and Collagen Deposition Induced by Tissue Expansion by Ledwon, Joanna K., Applebaum, Sarah A., Progri, Bianka, Han, Tianhong, Vignesh, Oveyaa, Gutowski, Kristof S., Chang, Alec B., Tepole, Adrian B., Gosain, Arun K.

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1: MicroRNAs: Potential For Molecular Modulation Of Mechanically-induced Skin Growth During TE by Ledwon, Joanna K., Stoehr, Jenna R., Vaca, Elbert E., Gosain, Arun K.

“…PurposeTissue expansion (TE) is commonly utilized to promote skin growth prior to reconstructing a defect or deformity. In spite of its ubiquitous use, the…”
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