Search Results - "Leducq, N"

Binding characteristics of SSR180575, a potent and selective peripheral benzodiazepine ligand by Vin, V, Leducq, N, Bono, F, Herbert, J.M

“…The peripheral benzodiazepine receptor (PBR), has been recently shown to play a key role in the regulation of the mitochondrial process leading to apoptosis,…”
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Early transitory rise in intracellular pH leads to Bax conformation change during ceramide-induced apoptosis by Belaud-Rotureau, M A, Leducq, N, Macouillard Poulletier de Gannes, F, Diolez, P, Lacoste, L, Lacombe, F, Bernard, P, Belloc, F

“…Ceramide can induce apoptosis through a caspase independent pathway. Bax has been described as able to kill cells in the absence of caspase activity, therefore…”
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TNF-alpha induced PMN apoptosis in whole human blood: Protective effect of SSR180575, a potent and selective peripheral benzodiazepine ligand by Leducq-Alet, N., Vin, V., Savi, P., Bono, F.

“…► TNF-alpha induces blood cell apoptosis in a whole blood assay. ► Blood cell apoptosis can be measured by PI staining with flow cytometry. ► SSR180575…”
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Mitochondrial and energetic dysfunctions of the liver during normothermic reperfusion: protective effect of cyclosporine and role of the mitochondrial permeability transition pore by Leducq, N, Delmas-Beauvieux, M.-C, Bourdel-Marchasson, I, Dufour, S, Gallis, J.-L, Canioni, P, Diolez, P

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Oxidative stress by monoamine oxidase mediates receptor-independent cardiomyocyte apoptosis by serotonin and postischemic myocardial injury by BIANCHI, Pascale, KUNDUZOVA, Oxana, PARINI, Angelo, MASINI, Emanuela, CAMBON, Claudie, BANI, Daniele, RAIMONDI, Laura, SEGUELAS, Marie-Helene, NISTRI, Silvia, COLUCCI, Wilson, LEDUCQ, Nathalie

“…Serotonin (5-hydroxytryptamine [5-HT]), released by activated platelets during cardiac ischemia, is metabolized by the mitochondrial enzyme monoamine oxidase A…”
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Liposomes as fatty acids carriers in isolated rat liver: effect on energy metabolism and on isolated mitochondria activity by Delmas-Beauvieux, M C, Leducq, N, Thiaudière, E, Diolez, P, Gin, H, Canioni, P, Gallis, J L

“…The effects of fatty acids (FA)-carrier, egg-lecithin liposomes (LIPO) as alternative to BSA, on ATP, glycogen and glucose contents in isolated perfused liver…”
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Role of peripheral benzodiazepine receptors in mitochondrial, cellular, and cardiac damage induced by oxidative stress and ischemia-reperfusion by Leducq, Nathalie, Bono, Françoise, Sulpice, Thierry, Vin, Valérie, Janiak, Philip, Fur, Gérard Le, O'Connor, Steve E, Herbert, Jean-Marc

“…Mitochondrial dysfunction has been identified as a possible early event in ischemia-reperfusion damage. The peripheral benzodiazepine receptor, a mitochondrial…”
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Involvement of peripheral benzodiazepine receptor in the oxidative stress, death-signaling pathways, and renal injury induced by ischemia-reperfusion by KUNDUZOVA, Oxana R, ESCOURROU, Ghislaine, DE LA FARGE, France, SALVAYRE, Robert, SEGUELAS, Marie-Hélène, LEDUCQ, Nathalie, BONO, Francoise, HERBERT, Jean-Marc, PARINI, Angelo

“…The peripheral benzodiazepine receptor (PBR) is a critical component of the mitochondrial permeability transition pore, which is involved in the regulation of…”
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Mitochondrial permeability transition during hypothermic to normothermic reperfusion in rat liver demonstrated by the protective effect of cyclosporin A by Leducq, N, Delmas-Beauvieux, M C, Bourdel-Marchasson, I, Dufour, S, Gallis, J L, Canioni, P, Diolez, P

“…The purpose of this study was to test the hypothesis that mitochondrial permeability transition might be implicated in mitochondrial and intact organ…”
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Mitochondria do not control heart bioenergetics by Diolez, Philippe, Raffard, Gérard, Simon, Cécile, Leducq, Nathalie, Dos, Santos Pierre, Canioni, Paul

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Mitochondrial impairment and recovery after heat shock treatment in a human microglial cell line by Macouillard-Poulletier de Gannes, Florence, Leducq, Nathalie, Diolez, Philippe, Belloc, Francis, Merle, Michel, Canioni, Paul, Voisin, Pierre-Jean

“…The application of a heat shock on the human microglial cell line (CHME 5) has been shown to cause cytoskeleton modifications and alterations in phosphorylated…”
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Liposomes as fatty acids carriers in isolated rat liver: effect on energy metabolism and on isolated mitochondria activity by Delmas-Beauvieux, M

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Top down analysis ceramide-induced mitochondrial dysfunctions: role of mitochondrial swelling by Leducq, Nathalie, Macouillard-Poulletier de Gannes, Florence, Rotureau, Marc-Antoine Belaud, Belloc, Francis, Voisin, Pierre, Canioni, Paul, Diolez, Philippe

“…Mitochondrial role in ceramide-induced apoptosis pathway remains unclear. Direct effects of ceramide on mitochondria (cytochrome c release, respiratory chain…”
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Use of spin-traps during warm ischemia-reperfusion in rat liver: comparative effect on energetic metabolism studied using 31P nuclear magnetic resonance by Delmas-Beauvieux, M C, Pietri, S, Culcasi, M, Leducq, N, Valeins, H, Liebgott, T, Diolez, P, Canioni, P, Gallis, J L

“…Detection of free radicals by electron spin resonance (ESR) proves the involvement of reactive oxygen species (ROS) in reperfused organ injuries. Spin-traps…”
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Use of spin-traps during warm ischemia-reperfusion in rat liver: comparative effect on energetic metabolism studied using31P nuclear magnetic resonance by Delmas-Beauvieux, M. C., Pietri, S., Culcasi, M., Leducq, N., Valeins, H., Liebgott, T., Diolez, P., Canioni, P., Gallis, J. L.

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Flow cytometric analysis of mitochondrial activity in situ: Application to acetylceramide‐induced mitochondrial swelling and apoptosis by Macouillard‐Poulletier de Gannes, Florence, Belaud‐Rotureau, Marc‐Antoine, Voisin, Pierre, Leducq, Nathalie, Belloc, Francis, Canioni, Paul, Diolez, Philippe

“…Changes in mitochondrial matrix volume were studied both on isolated mitochondria and in situ on CHME 5 human microglia and monoblastoid U 937 cells using…”
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