Search Results - "Leduc, R"

Tumor-on-a-chip for integrating a 3D tumor microenvironment: chemical and mechanical factors by Wan, L, Neumann, C A, LeDuc, P R

“…Tumor progression, including metastasis, is significantly influenced by factors in the tumor microenvironment (TME) such as mechanical force, shear stress,…”
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Characterization of neural mechanotransduction response in human traumatic brain injury organoid model by Beltrán, Susana M., Bobo, Justin, Habib, Ahmed, Kodavali, Chowdari V., Edwards, Lincoln, Mamindla, Priyadarshini, Taylor, Rebecca E., LeDuc, Philip R., Zinn, Pascal O.

“…The ability to model physiological systems through 3D neural in-vitro systems may enable new treatments for various diseases while lowering the need for…”
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Inflammation in Areas of Tubular Atrophy in Kidney Allograft Biopsies: A Potent Predictor of Allograft Failure by Mannon, R. B., Matas, A. J., Grande, J., Leduc, R., Connett, J., Kasiske, B., Cecka, J. M., Gaston, R. S., Cosio, F., Gourishankar, S., Halloran, P. F., Hunsicker, L., Rush, D.

“…The Banff scoring schema provides a common ground to analyze kidney transplant biopsies. Interstitial inflammation (i) and tubulitis (t) in areas of viable…”
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Author Correction: Characterization of neural mechanotransduction response in human traumatic brain injury organoid model by Beltrán, Susana M., Bobo, Justin, Habib, Ahmed, Kodavali, Chowdari V., Edwards, Lincoln, Mamindla, Priyadarshini, Taylor, Rebecca E., LeDuc, Philip R., Zinn, Pascal O.

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Microbial electricity generation via microfluidic flow control by Li, Zhiqiang, Zhang, Ying, LeDuc, Philip R., Gregory, Kelvin B.

“…Next generation battery technology is rapidly evolving to meet the demand for higher power densities and smaller footprints through novel catalysts and battery…”
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Fabrication of circular microfluidic channels by combining mechanical micromilling and soft lithography by Wilson, Mary E, Kota, Nithyanand, Kim, YongTae, Wang, Yadong, Stolz, Donna B, LeDuc, Philip R, Ozdoganlar, O Burak

“…The fabrication of microfluidic channels with complex three-dimensional (3D) geometries presents a major challenge to the field of microfluidics, because…”
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Toward Vasculature in Skeletal Muscle-on-a-Chip through Thermo-Responsive Sacrificial Templates by Wan, Li, Flegle, James, Ozdoganlar, Burak, LeDuc, Philip

“…Developing new approaches for vascularizing synthetic tissue systems will have a tremendous impact in diverse areas. One area where this is particularly…”
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Novel Tools in Determining the Physiological Demands and Nutritional Practices of Ontario FireRangers during Fire Deployments by Robertson, A H, Larivière, C, Leduc, C R, McGillis, Z, Eger, T, Godwin, A, Larivière, M, Dorman, S C

“…The seasonal profession of wildland fire fighting in Canada requires individuals to work in harsh environmental conditions that are physically demanding. The…”
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Proteoforms in Peripheral Blood Mononuclear Cells as Novel Rejection Biomarkers in Liver Transplant Recipients by Toby, T. K., Abecassis, M., Kim, K., Thomas, P. M., Fellers, R. T., LeDuc, R. D., Kelleher, N. L., Demetris, J., Levitsky, J.

“…Biomarker profiles of acute rejection in liver transplant recipients could enhance the diagnosis and management of recipients. Our aim was to identify…”
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Lower Calcineurin Inhibitor Doses in Older Compared to Younger Kidney Transplant Recipients Yield Similar Troughs by Jacobson, P. A., Schladt, D., Oetting, W. S., Leduc, R., Guan, W., Matas, A. J., Israni, A.

“…The number of older adults undergoing kidney transplantation has increased, yet little is known about calcineurin inhibitor (CNI) metabolism in this group. We…”
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Probing coordinated co-culture cancer related motility through differential micro-compartmentalized elastic substrates by Chou, Szu-Yuan, Lin, Chang-You, Cassino, Theresa, Wan, Li, LeDuc, Philip R.

“…Cell development and behavior are driven by internal genetic programming, but the external microenvironment is increasingly recognized as a significant factor…”
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Geometric effects in microfluidics on heterogeneous cell stress using an Eulerian-Lagrangian approach by Warren, K M, Mpagazehe, J N, LeDuc, P R, Higgs, 3rd, C F

“…The response of individual cells at the micro-scale in cell mechanics is important in understanding how they are affected by changing environments. To control…”
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Investigating Circular Dorsal Ruffles through Varying Substrate Stiffness and Mathematical Modeling by Zeng, Yukai, Lai, Tanny, Koh, Cheng Gee, LeDuc, Philip R., Chiam, K.-H.

“…Circular dorsal ruffles (CDRs) are transient actin-rich ringlike structures that form on the dorsal surface of growth-factor stimulated cells. However, the…”
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Feeding ecology of eastern North Pacific killer whales Orcinus orca from fatty acid, stable isotope, and organochlorine analyses of blubber biopsies by HERMAN, D. P, BURROWS, D. G, WADE, P. R, DURBAN, J. W, MATKIN, C. O, LEDUC, R. G, BARRETT-LENNARD, L. G, KRAHN, M. M

“…Blubber biopsy samples from eastern North Pacific killer whales Orcinus orca were analyzed for fatty acids, carbon and nitrogen stable isotopes and…”
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Understanding sensory nerve mechanotransduction through localized elastomeric matrix control by Lin, Yi-Wen, Cheng, Chao-Min, Leduc, Philip R, Chen, Chih-Cheng

“…While neural systems are known to respond to chemical and electrical stimulation, the effect of mechanics on these highly sensitive cells is still not well…”
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Signaling switch of the urotensin II vasosactive peptide GPCR: prototypic chemotaxic mechanism in glioma by Lecointre, C, Desrues, L, Joubert, J E, Perzo, N, Guichet, P-O, Le Joncour, V, Brulé, C, Chabbert, M, Leduc, R, Prézeau, L, Laquerrière, A, Proust, F, Gandolfo, P, Morin, F, Castel, H

“…Multiform glioblastomas (GBM) are the most frequent and aggressive primary brain tumors in adults. The poor prognosis is due to neo-angiogenesis and cellular…”
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Mechanochemical actuators of embryonic epithelial contractility by Kim, YongTae, Hazar, Melis, Vijayraghavan, Deepthi S., Song, Jiho, Jackson, Timothy R., Joshi, Sagar D., Messner, William C., Davidson, Lance A., LeDuc, Philip R.

“…Spatiotemporal regulation of cell contractility coordinates cell shape change to construct tissue architecture and ultimately directs the morphology and…”
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Defining the role of syndecan-4 in mechanotransduction using surface-modification approaches by Bellin, Robert M, Kubicek, James D, Frigault, Matthew J, Kamien, Andrew J, Steward, Robert L. Jr, Barnes, Hillary M, DiGiacomo, Michael B, Duncan, Luke J, Edgerly, Christina K, Morse, Elizabeth M, Park, Chan Young, Fredberg, Jeffrey J, Cheng, Chao-Min, LeDuc, Philip R

“…The ability of cells to respond to external mechanical stimulation is a complex and robust process involving a diversity of molecular interactions. Although…”
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Towards an in vivo biologically inspired nanofactory by LeDuc, Philip R, Wong, Michael S, Ferreira, Placid M, Groff, Richard E, Haslinger, Kiryn, Koonce, Michael P, Lee, Woo Y, Love, J. Christopher, McCammon, J. Andrew, Monteiro-Riviere, Nancy A, Rotello, Vincent M, Rubloff, Gary W, Westervelt, Robert, Yoda, Minami

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Genetic variation in blue whales in the eastern pacific: implication for taxonomy and use of common wintering grounds by Leduc, R. G., Archer, F. I., Lang, A. R., Martien, K. K., Hancock‐Hanser, B., Torres‐Florez, J. P., Hucke‐Gaete, R., Rosenbaum, H. C., Waerebeek, K., Brownell, R. L., Taylor, B. L.

“…Many aspects of blue whale biology are poorly understood. Some of the gaps in our knowledge, such as those regarding their basic taxonomy and seasonal…”
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