Search Results - "Ledreux, A"

Regional binding of tau and amyloid PET tracers in Down syndrome autopsy brain tissue by Lemoine, L, Ledreux, A, Mufson, E J, Perez, S E, Simic, G, Doran, E, Lott, I, Carroll, S, Bharani, K, Thomas, S, Gilmore, A, Hamlett, E D, Nordberg, A, Granholm, A C

“…Tau pathology is a major age-related event in Down syndrome with Alzheimer's disease (DS-AD). Although recently, several different Tau PET tracers have been…”
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Evidence for saxitoxins production by the cyanobacterium Aphanizomenon gracile in a French recreational water body by Ledreux, A., Thomazeau, S., Catherine, A., Duval, C., Yéprémian, C., Marie, A., Bernard, C.

“…In the last few years, a scientific consensus has emerged regarding the increasing frequency and severity of cyanobacterial blooms in freshwater environments…”
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BDNF Responses in Healthy Older Persons to 35 Minutes of Physical Exercise, Cognitive Training, and Mindfulness: Associations with Working Memory Function by Håkansson, Krister, Ledreux, Aurélie, Daffner, Kirk, Terjestam, Yvonne, Bergman, Patrick, Carlsson, Roger, Kivipelto, Miia, Winblad, Bengt, Granholm, Ann-Charlotte, Mohammed, Abdul Kadir H

“…Brain-derived neurotrophic factor (BDNF) has a central role in brain plasticity by mediating changes in cortical thickness and synaptic density in response to…”
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Altered levels of plasma neuron‐derived exosomes and their cargo proteins characterize acute and chronic mild traumatic brain injury by Goetzl, Edward J., Elahi, Fanny M., Mustapic, Maja, Kapogiannis, Dimitrios, Pryhoda, Moira, Gilmore, Anah, Gorgens, Kimberly A., Davidson, Bradley, Granholm, Anne‐Charlotte, Ledreux, Aurélie

“…ABSTRACTNeuron‐derived exosomes (NDEs) were enriched by anti‐L1CAM antibody immunoabsorption from plasmas of subjects ages 18–26 yr within 1 wk after a…”
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Detrimental effects of a high fat/high cholesterol diet on memory and hippocampal markers in aged rats by Ledreux, Aurélie, Wang, Xiuzhe, Schultzberg, Marianne, Granholm, Ann-Charlotte, Freeman, Linnea R.

“…•Young and Aged rats were exposed for 6 months to a high fat high cholesterol diet (HFHC).•Cognitive performance, neuroinflammation markers and phosphorylated…”
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Exosomal biomarkers in Down syndrome and Alzheimer's disease by Hamlett, Eric D., Ledreux, Aurélie, Potter, Huntington, Chial, Heidi J., Patterson, David, Espinosa, Joaquin M., Bettcher, Brianne M., Granholm, Ann-Charlotte

“…Every person with Down syndrome (DS) has the characteristic features of Alzheimer's disease (AD) neuropathology in their brain by the age of forty, and most go…”
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RvE1 treatment prevents memory loss and neuroinflammation in the Ts65Dn mouse model of Down syndrome by Hamlett, Eric D., Hjorth, Erik, Ledreux, Aurélie, Gilmore, Anah, Schultzberg, Marianne, Granholm, Ann Charlotte

“…Inflammation can be resolved by pro‐homeostatic lipids called specialized pro‐resolving mediators (SPMs) upon activation of their receptors. Dysfunctional…”
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BDNF Mediates Improvement in Cognitive Performance after Computerized Cognitive Training (4326) by Nicastri, Casey, Simon, Sharon Sanz, McFeeley, Brittany, Ledreux, Aurélie, Håkansson, Krister, Granholm, Ann-Charlotte, Mohammed, Abdul, Daffner, Kirk

“…Abstract only…”
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Neuronal exosomes reveal Alzheimer's disease biomarkers in Down syndrome by Hamlett, Eric D, Goetzl, Edward J, Ledreux, Aurélie, Vasilevko, Vitaly, Boger, Heather A, LaRosa, Angela, Clark, David, Carroll, Steven L, Carmona-Iragui, María, Fortea, Juan, Mufson, Elliott J, Sabbagh, Marwan, Mohammed, Abdul H, Hartley, Dean, Doran, Eric, Lott, Ira T, Granholm, Ann-Charlotte

“…Abstract Introduction Individuals with Down syndrome (DS) exhibit Alzheimer's disease (AD) neuropathology and dementia early in life. Blood biomarkers of AD…”
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Differential Effects of Physical Exercise, Cognitive Training, and Mindfulness Practice on Serum BDNF Levels in Healthy Older Adults: A Randomized Controlled Intervention Study by Ledreux, Aurélie, Håkansson, Krister, Carlsson, Roger, Kidane, Mhretab, Columbo, Laura, Terjestam, Yvonne, Ryan, Eliza, Tusch, Erich, Winblad, Bengt, Daffner, Kirk, Granholm, Ann-Charlotte, Mohammed, Abdul Kadir H

“…Previous studies have indicated that an active lifestyle is associated with better brain health and a longer life, compared to a more sedentary lifestyle…”
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Assessment of brain‐derived extracellular vesicle enrichment for blood biomarker analysis in age‐related neurodegenerative diseases: An international overview by Badhwar, AmanPreet, Hirschberg, Yael, Valle‐Tamayo, Natalia, Iulita, M. Florencia, Udeh‐Momoh, Chinedu T., Matton, Anna, Tarawneh, Rawan M., Rissman, Robert A., Ledreux, Aurélie, Winston, Charisse N., Haqqani, Arsalan S.

“…INTRODUCTION Brain‐derived extracellular vesicles (BEVs) in blood allows for minimally‐invasive investigations of central nervous system (CNS) ‐specific…”
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Suitability of the Neuro-2a cell line for the detection of palytoxin and analogues (neurotoxic phycotoxins) by Ledreux, Aurélie, Krys, Sophie, Bernard, Cécile

“…Palytoxin and related compounds are neurotoxic phycotoxins produced by benthic microalgae belonging to the genus Ostreopsis. For several years this family of…”
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First report in a river in France of the benthic cyanobacterium Phormidium favosum producing anatoxin-a associated with dog neurotoxicosis by Gugger, Muriel, Lenoir, Séverine, Berger, Céline, Ledreux, Aurélie, Druart, Jean-Claude, Humbert, Jean-François, Guette, Catherine, Bernard, Cécile

“…The first identification of anatoxin-a in a French lotic system is reported. Rapid deaths of dogs occurred in 2003 after the animals drank water from the…”
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BDNF mediates improvement in cognitive performance after computerized cognitive training in healthy older adults by Nicastri, Casey M., McFeeley, Brittany M., Simon, Sharon S., Ledreux, Aurélie, Håkansson, Krister, Granholm, Ann‐Charlotte, Mohammed, Abdul H., Daffner, Kirk R.

“…Introduction The often‐cited mechanism linking brain‐derived neurotrophic factor (BDNF) to cognitive health has received limited experimental study. There is…”
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Resolvin E1 Reduces Inflammation and Enhances Memory in the Ts65Dn Mouse Model of Down Syndrome by Hamlett, E, Wang, X, Ledreux, A, Hjorth, E, Granholm, AC, Schultzberg, M

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Application of the neuroblastoma assay for paralytic shellfish poisons to neurotoxic freshwater cyanobacteria: interlaboratory calibration, and comparison with other methods of analysis by Humpage, A.R, Ledreux, A, Fanok, S, Bernard, C, Briand, J.F, Eaglesham, G, Papageorgiou, J, Nicholson, B, Steffensen, D

“…Paralytic shellfish poisons (PSPs) are produced by freshwater cyanobacteria and pose a threat to human and animal drinking‐water supplies. The wide range of…”
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A non-radioactive ligand-binding assay for detection of cyanobacterial anatoxins using Torpedo electrocyte membranes by Aráoz, Rómulo, Herdman, Michael, Rippka, Rosmarie, Ledreux, Aurélie, Molgó, Jordi, Changeux, Jean-Pierre, Tandeau de Marsac, Nicole, Nghiêm, Hoàng-Oanh

“…Anatoxin-a (ANTX) and homoanatoxin-a (HANTX), neurotoxins exclusively produced by cyanobacteria (LD 50 200–250 μg kg −1, i.p. mouse), are agonists of the…”
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