Search Results - "Ledin, Evgeny"
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Utility of public knowledge bases for the interpretation of comprehensive tumor molecular profiling results
Published in Clinical and experimental medicine (01-10-2023)“…With the growing use of comprehensive tumor molecular profiling (CTMP), the therapeutic landscape of cancer is rapidly evolving. NGS produces large amounts of…”
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Effectiveness and tolerability of FOLFOXIRI regimen in the third- and subsequent lines of therapy in patients with metastatic colorectal cancer
Published in Journal of clinical oncology (20-05-2021)“…Abstract only e15584 Background: Options of therapy are limited for patients with colorectal cancer who developed disease progression during standard 5-FU-,…”
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Clinical application of next-generation sequencing in cancer patients
Published in Journal of clinical oncology (20-05-2021)“…Abstract only e15090 Background: Next-generation sequencing (NGS) has been moving rapidly from pure cancer genomics research towards clinical oncology to…”
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The role of surgery (metastasectomy) in advanced BRAF positive melanoma during modern therapy
Published in Journal of clinical oncology (01-06-2022)“…e21512 Background: Improved overall survival in patients undergoing metаstasectomy for melanoma have been reported in several retrospective studies before era…”
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Phase Ib study of BI 836880 (VEGF/Ang2 inhibitor) plus ezabenlimab (BI 754091; anti-PD-1 antibody) in patients (pts) with advanced hepatocellular carcinoma (HCC)
Published in Journal of clinical oncology (01-02-2022)“…Abstract only 434 Background: Combination of anti-VEGF compounds and immune checkpoint inhibitors is an approved therapy across multiple solid tumors,…”
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Utility of public Knowledge Bases (KB) for comprehensive tumor molecular profiling (CTMP) result interpretation
Published in Journal of clinical oncology (01-06-2022)“…e15119 Background: With the spread of CTMP in cancer patient management and expansion of molecular-targeted treatment opportunities, resources for quick and…”
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7
Failure of immune checkpoint inhibitors for microsatellite instability-positive pancreatic adenocarcinoma with atypical pattern of short tandem repeat mutation
Published in Immunotherapy (19-07-2024)“…Microsatellite instability (MSI) is an important biomarker in cancer. While routine methods can detect MSI in certain tumor types, in other tumor types the…”
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Multicenter observational prospective study of nivolumab (Nivo) as 2+ line treatment in advanced refractory NSCLC pts: Clinical and quality of life outcomes
Published in Journal of clinical oncology (20-05-2019)“…Abstract only e20567 Background: We aimed to evaluate clinical and quality of life (QoL) outcomes of Nivo as 2+ line treatment in NSCLC pts within expanded…”
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