Search Results - "Ledet, T"

Arterial osteoprotegerin: increased amounts in diabetes and modifiable synthesis from vascular smooth muscle cells by insulin and TNF-alpha by Olesen, P, Ledet, T, Rasmussen, L M

“…Extracellular matrix modifications and linear medial calcifications are elements of diabetic macroangiopathy. We hypothesised that the bone-related protein…”
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Rough-Form Lipopolysaccharide Increases Apoptosis in Human CD4+ and CD8+ T Lymphocytes by Nielsen, J. S., Larsson, A., Ledet, T., Turina, M., Tønnesen, E., Krog, J.

“…Immunosuppression induced by lymphocyte apoptosis is considered an important factor in the pathogenesis of sepsis and has been demonstrated in both animal…”
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Osteoprotegerin and diabetic macroangiopathy by Rasmussen, L M, Ledet, T

“…Osteoprotegerin (OPG) is a bone-related protein that is also present in the vasculature. Recent data suggest that it may play a special role in arterial…”
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Diverse effects of inhibition of 3-hydroxy-3-methylglutaryl-CoA reductase on the expression of VCAM-1 and E-selectin in endothelial cells by Rasmussen, L M, Hansen, P R, Nabipour, M T, Olesen, P, Kristiansen, M T, Ledet, T

“…The expression of monocyte adhesion molecules, such as VCAM-1 (vascular cell adhesion molecule-1) and E-selectin, on the surface of the endothelium is an…”
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Effects of androstenedione, insulin and luteinizing hormone on steroidogenesis in human granulosa luteal cells by Greisen, S., Ledet, T., Ovesen, P.

“…BACKGROUND: The present study was conducted to investigate the effect of androstenedione, insulin and LH on human granulosa cell oestrogen and progesterone…”
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Effects of glucose, glycerol, 3-hydroxybutyrate, insulin, and leptin on placental growth hormone secretion in placental explants by Fuglsang, J, Møller, N, Ledet, T, Ovesen, P

“…Placental growth hormone (PGH) is secreted from the syncytiotrophoblast in increasing amounts during pregnancy. The physiology and regulation of PGH is not…”
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Arterial osteoprotegerin : increased amounts in diabetes and modifiable synthesis from vascular smooth muscle cells by insulin and TNF by OLESEN, P, LEDET, T, RASMUSSEN, L. M

“…Extracellular matrix modifications and linear medial calcifications are elements of diabetic macroangiopathy. We hypothesised that the bone-related protein…”
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Expression of somatostatin receptors on human pituitary adenomas in vivo and ex vivo by NIELSEN, S, MELLEMKJAER, S, RASMUSSEN, L. M, LEDET, T, OLSEN, N, BOJSEN-MØLLER, M, ASTRUP, J, WEEKE, J, JØRGENSEN, J. O. L

“…The distribution and biologic activity of somatostatin receptor subtypes (SSTR) in pituitary adenomas is not clarified, especially regarding clinically…”
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The use of transgenic animals in the study of diabetic kidney disease by Wogensen, L, Krag, S, Chai, Q, Ledet, T

“…Diabetic nephropathy is one of the most common diseases leading to fibrosis and end-stage renal disease (ESRD) world wide. Under normal conditions, a delicate…”
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Glycosaminoglycans in the human aorta in diabetes mellitus: a study of tunica media from areas with and without atherosclerotic plaque by Heickendorff, L, Ledet, T, Rasmussen, L M

“…Alterations in the connective tissue of the arterial wall have been suggested to play a role in the development of macrovascular disease in diabetes mellitus…”
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Production of hyaluronan and chondroitin sulphate proteoglycans from human arterial smooth muscle : the effect of glucose, insulin, IGF-I or growth hormone by ERIKSTRUP, Christian, PEDERSEN, Lene-Marie, HEICKENDORFF, Lene, LEDET, Thomas, RASMUSSEN, Lars M

“…Although it is recognized that the extracellular matrix is important for cell proliferation, migration and metabolism of growth factors, the regulation of the…”
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E-selectin-inducing activity in plasma from type 2 diabetic patients with maculopathy by Knudsen, S T, Foss, C H, Poulsen, P L, Bek, T, Ledet, T, Mogensen, C E, Rasmussen, L M

“…Diabetic maculopathy (DMa) is a leading cause of visual loss in the western world. We examined whether plasma from type 2 diabetic patients with DMa contains…”
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An experimental model for stricture studies in the anterior urethra of the male rabbit by Andersen, H L, Duch, B U, Nielsen, J B, Joergensen, B, Ledet, T

“…In this study, an animal model was developed for the examination of urethral strictures (US). Through a resectoscope, a resection was made in the urethras of…”
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Aortic collagen alterations in human diabetes mellitus. Changes in basement membrane collagen content and in the susceptibility of total collagen to cyanogen bromide solubilisation by RASMUSSEN, L. M, LEDET, T

“…Structural alterations in arterial extracellular matrix components have been suggested to play a role in the development of arterial disease among patients…”
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Aortic atherosclerosis in diabetes mellitus is associated with an insertion/deletion polymorphism in the angiotensin I-converting enzyme gene : No relation between the polymorphism and aortic collagen content by RAMUSSEN, L. M, LEDET, T

“…An insertion(I)/deletion(D) polymorphism in the angiotensin I-converting enzyme (ACE) gene seems to be associated with clinical heart disease in patients with…”
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Increased expression of vascular cell adhesion molecule-1 (VCAM-1) in cultured endothelial cells exposed to serum from type 1 diabetic patients: no effects of high glucose concentrations by Ramussen, L. M., Schmitz, O., Ledet, T.

“…Activation of the arterial endothelium may play an important role in the development of an atherosclerosis-prone vascular wall in diabetes. The induction of…”
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Expression of leptin receptor isoforms and effects of leptin on the proliferation and hormonal secretion in human pituitary adenomas by Kristiansen, M T, Clausen, L R, Nielsen, S, Blaabjerg, O, Ledet, T, Rasmussen, L M, Jørgensen, J O L

“…To pursue whether leptin regulates anterior pituitary cells, we studied the ex vivo expression of several isoforms of the leptin receptor (OB-R) as well as the…”
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Effect of growth hormone on steroidogenesis, insulin-like growth factor-I (IGF-I) and IGF-binding protein-1 production and DNA synthesis in cultured human luteinized granulosa cells by Ovesen, P, Ingerslev, H J, Orskov, H, Ledet, T

“…Numerous clinical and experimental observations have suggested that GH is important in ovarian function. We have investigated the effect of GH alone and GH in…”
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Diabetic macroangiopathy: quantitative histopathological studies of the extramural coronary arteries from Type 2 (non-insulin-dependent) diabetic patients by DYBDAHKL, H, LEDET, T

“…A morphometric study was performed on histological sections of the extramural coronary arteries from 10 Type 2 (non-insulin-dependent) diabetic patients and 10…”
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Under control of the Ren-1c promoter, locally produced transforming growth factor-beta1 induces accumulation of glomerular extracellular matrix in transgenic mice by Wogensen, L, Nielsen, C B, Hjorth, P, Rasmussen, L M, Nielsen, A H, Gross, K, Sarvetnick, N, Ledet, T

“…Under control of the Ren-1c promoter, locally produced transforming growth factor-beta1 induces accumulation of glomerular extracellular matrix in transgenic…”
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