Search Results - "Ledet, Melissa M"

Secreted sphingomyelins modulate low mammary cancer incidence observed in certain mammals by Ledet, Melissa M., Harman, Rebecca M., Fan, Jennifer C., Schmitt-Matzen, Emily, Diaz-Rubio, Maria Elena, Zhang, Sheng, Van de Walle, Gerlinde R.

“…Determining mechanisms that naturally protect species from developing cancer is critical in order to prevent and treat cancer. Here, we describe a novel…”
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Conserved and variable: Understanding mammary stem cells across species by Rauner, Gat, Ledet, Melissa M., Van de Walle, Gerlinde R.

“…Postnatal mammary gland development requires the presence of mammary stem and progenitor cells (MaSC), which give rise to functional milk‐secreting cells and…”
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BB-Cl-Amidine as a novel therapeutic for canine and feline mammary cancer via activation of the endoplasmic reticulum stress pathway by Ledet, Melissa M, Anderson, Robyn, Harman, Rebecca, Muth, Aaron, Thompson, Paul R, Coonrod, Scott A, Van de Walle, Gerlinde R

“…Mammary cancer is highly prevalent in dogs and cats and results in a poor prognosis due to critically lacking viable treatment options. Recent human and mouse…”
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Differential signaling pathway activation in 7,12-dimethylbenz[a] anthracene (DMBA)-treated mammary stem/progenitor cells from species with varying mammary cancer incidence by Ledet, Melissa M, Oswald, Meghan, Anderson, Robyn, Van de Walle, Gerlinde R

“…A natural variation exists in the susceptibility to mammary cancer among wild and domestic mammalian species. Mammary stem/progenitor cells (MaSC) represent a…”
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The secretome from bovine mammosphere-derived cells (MDC) promotes angiogenesis, epithelial cell migration, and contains factors associated with defense and immunity by Ledet, Melissa M., Vasquez, Amy K., Rauner, Gat, Bichoupan, Allison A., Moroni, Paolo, Nydam, Daryl V., Van de Walle, Gerlinde R.

“…Treatment of bovine mastitis with intramammary antibiotics is common, yet several concerns exist including failed efficacy for individual hosts or pathogens…”
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