Search Results - "Lederer, R."

Sphingolipids control dermal fibroblast heterogeneity by Capolupo, Laura, Khven, Irina, Lederer, Alex R, Mazzeo, Luigi, Glousker, Galina, Ho, Sylvia, Russo, Francesco, Montoya, Jonathan Paz, Bhandari, Dhaka R, Bowman, Andrew P, Ellis, Shane R, Guiet, Romain, Burri, Olivier, Detzner, Johanna, Muthing, Johannes, Homicsko, Krisztian, Kuonen, François, Gilliet, Michel, Spengler, Bernhard, Heeren, Ron M A, Dotto, G Paolo, La Manno, Gioele, D'Angelo, Giovanni

“…Human cells produce thousands of lipids that change during cell differentiation and can vary across individual cells of the same type. However, we are only…”
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Radiation exposure induces inflammasome pathway activation in immune cells by Stoecklein, Veit M, Osuka, Akinori, Ishikawa, Shizu, Lederer, Madeline R, Wanke-Jellinek, Lorenz, Lederer, James A

“…Radiation exposure induces cell and tissue damage, causing local and systemic inflammatory responses. Because the inflammasome pathway is triggered by cell…”
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Molecular architecture of the developing mouse brain by La Manno, Gioele, Siletti, Kimberly, Furlan, Alessandro, Gyllborg, Daniel, Vinsland, Elin, Mossi Albiach, Alejandro, Mattsson Langseth, Christoffer, Khven, Irina, Lederer, Alex R., Dratva, Lisa M., Johnsson, Anna, Nilsson, Mats, Lönnerberg, Peter, Linnarsson, Sten

“…The mammalian brain develops through a complex interplay of spatial cues generated by diffusible morphogens, cell–cell interactions and intrinsic genetic…”
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Survey of tail injuries sustained by working gundogs and terriers in Scotland by Lederer, R., Bennett, D., Parkin, T.

“…Working dog owners in Scotland were invited to take part in an internet survey regarding the 2010/2011 shooting season, which was designed to estimate the…”
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The prevalence of tail injuries in working and non-working breed dogs visiting veterinary practices in Scotland by Cameron, N., Lederer, R., Bennett, D., Parkin, T.

“…The aim of this paper was to estimate the prevalence of tail injuries that required veterinary examination in different breeds of dog in Scotland. The study…”
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Defective Excitation-Contraction Coupling in Experimental Cardiac Hypertrophy and Heart Failure by Gómez, A. M., Valdivia, H. H., Cheng, H., Lederer, Miriam R., Santana, L. F., Cannell, M. B., McCune, S. A., Altschuld, R. A., Lederer, W. J.

“…Cardiac hypertrophy and heart failure caused by high blood pressure were studied in single myocytes taken from hypertensive rats (Dahl SS/Jr) and SH-HF rats in…”
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The emergence and promise of single-cell temporal-omics approaches by Lederer, Alex R, La Manno, Gioele

“…[Display omitted] •Pseudotime trajectory inference algorithms harness the variance of asynchronously changing cells.•RNA velocity uses expression dynamics to…”
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Clinically compliant cryopreservation of differentiated retinal pigment epithelial cells by Baqué-Vidal, Laura, Main, Heather, Petrus-Reurer, Sandra, Lederer, Alex R., Beri, Nefeli-Eirini, Bär, Frederik, Metzger, Hugo, Zhao, Cheng, Efstathopoulos, Paschalis, Saietz, Sarah, Wrona, Andreas, Jaberi, Elham, Willenbrock, Hanni, Reilly, Hazel, Hedenskog, Mona, Moussaud-Lamodière, Elisabeth, Kvanta, Anders, Villaescusa, J. Carlos, La Manno, Gioele, Lanner, Fredrik

“…Age-related macular degeneration (AMD) is the most common cause of blindness in elderly patients within developed countries, affecting more than 190 million…”
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Molecular profiling of stem cell-derived retinal pigment epithelial cell differentiation established for clinical translation by Petrus-Reurer, Sandra, Lederer, Alex R, Baqué-Vidal, Laura, Douagi, Iyadh, Pannagel, Belinda, Khven, Irina, Aronsson, Monica, Bartuma, Hammurabi, Wagner, Magdalena, Wrona, Andreas, Efstathopoulos, Paschalis, Jaberi, Elham, Willenbrock, Hanni, Shimizu, Yutaka, Villaescusa, J Carlos, André, Helder, Sundstrӧm, Erik, Bhaduri, Aparna, Kriegstein, Arnold, Kvanta, Anders, La Manno, Gioele, Lanner, Fredrik

“…Human embryonic stem cell-derived retinal pigment epithelial cells (hESC-RPE) are a promising cell source to treat age-related macular degeneration (AMD)…”
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Calcium sparks and [Ca2+]i waves in cardiac myocytes by Cheng, H, Lederer, M R, Lederer, W J, Cannell, M B

“…Local elevations in intracellular calcium ("Ca2+ sparks") in heart muscle are elementary sarcoplasmic reticulum (SR) Ca(2+)-release events. Ca2+ sparks occur…”
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Nasal carriage of meticillin resistant Staphylococcus aureus: the prevalence, patients at risk and the effect of elimination on outcomes among outclinic haemodialysis patients by Lederer, S R, Riedelsdorf, G, Schiffl, H

“…Haemodialysis (HD) patients with meticillin-resistant Staphylococcus aureus (MRSA) infections face high morbidity and mortality. Nasal carriage of…”
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Provenance of LGM glacial till (sand fraction) across the Ross embayment, Antarctica by Licht, Kathy J., Lederer, Jason R., Jeffrey Swope, R.

“…The provenance of Late Quaternary Ross Embayment till was investigated by comparing the coarse sand composition of East and West Antarctic source area tills…”
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Erythropoiesis-stimulating agents, hypertension and left ventricular hypertrophy in the chronic kidney disease patient by Schmid, Holger, Schiffl, Helmut, Lederer, Stephan R

“…PURPOSE OF REVIEWLeft-ventricular hypertrophy (LVH) represents an important marker of cardiovascular morbidity and mortality. Numerous noninterventional…”
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Impact of humoral alloreactivity early after transplantation on the long-term survival of renal allografts by Lederer, Stephan R., Kluth-Pepper, Brigitte, Schneeberger, Helmut, Albert, Ekkehard, Land, Walter, Feucht, Helmut E.

“…Impact of humoral alloreactivity early after transplantation on the long-term survival of renal allografts. The contribution of humoral alloreactivity to the…”
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Frequency of feline diabetes mellitus and breed predisposition in domestic cats in Australia by Lederer, R., Rand, J.S., Jonsson, N.N., Hughes, I.P., Morton, J.M.

“…The frequency of diabetes mellitus is described for cats that received veterinary care from two large feline-only clinics in Brisbane, Australia. Frequency was…”
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New strategies for managing anemia of chronic kidney disease by Schmid, Holger, Schiffl, Helmut, Lederer, Stephan R

“…Anemia is a prevalent and premature comorbidity in chronic kidney disease (CKD) and associated with multiple adverse clinical consequences including increased…”
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Out-of-Hospital Birth in Medical Education: A Thematic Analysis of Question Banks for Medical Licensing Examinations in the United States by Lederer, Magdalene R, Hurst, Daniel J

“…This study assessed the content of US Medical Licensing Examination question banks with regard to out-of-hospital births and whether the questions aligned with…”
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Multiplexed precision genome editing with trackable genomic barcodes in yeast by Roy, Kevin R, Smith, Justin D, Vonesch, Sibylle C, Lin, Gen, Tu, Chelsea Szu, Lederer, Alex R, Chu, Angela, Suresh, Sundari, Nguyen, Michelle, Horecka, Joe, Tripathi, Ashutosh, Burnett, Wallace T, Morgan, Maddison A, Schulz, Julia, Orsley, Kevin M, Wei, Wu, Aiyar, Raeka S, Davis, Ronald W, Bankaitis, Vytas A, Haber, James E, Salit, Marc L, St.Onge, Robert P, Steinmetz, Lars M

“…A method to introduce defined mutations into the yeast genome enables saturation mutagenesis of a gene and genome-scale introduction of genetic variants. Our…”
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Statistical inference with a manifold-constrained RNA velocity model uncovers cell cycle speed modulations by Lederer, Alex R, Leonardi, Maxine, Talamanca, Lorenzo, Bobrovskiy, Daniil M, Herrera, Antonio, Droin, Colas, Khven, Irina, Carvalho, Hugo J F, Valente, Alessandro, Dominguez Mantes, Albert, Mulet Arabí, Pau, Pinello, Luca, Naef, Felix, La Manno, Gioele

“…Across biological systems, cells undergo coordinated changes in gene expression, resulting in transcriptome dynamics that unfold within a low-dimensional…”
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Effects of mycophenolate mofetil on donor-specific antibody formation in renal transplantation by Lederer, Stephan R, Friedrich, Nicole, Banas, Bernhard, von Welser, Georg, Albert, Ekkehard D, Sitter, Thomas

“…:  Background:  Mycophenolate mofetil (MMF) is a routinely used immunosuppressive agent that selectively blocks T‐ and B‐lymphocyte proliferation. The present…”
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