Search Results - "Ledebur, H C"

Lymphoid signal transduction mechanisms linked to cellular prion protein by Mazzoni, I E, Ledebur, Jr, H C, Paramithiotis, E, Cashman, N

“…The normal cellular isoform of the prion protein (PrPC) is a glycosylphosphatidylinositol-anchored cell surface protein that is expressed widely, including in…”
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Dendritic cell delivery of plasmid DNA: Applications for controlled genetic immunization by MUMPER, Russell J, LEDEBUR, Harry C

“…Positive human clinical data using biolistic-mediated gene transfer (i.e., gene gun) to administer a nucleic acid-based Hepatitis B vaccine has validated…”
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Synergistic effect of formulated plasmid and needle-free injection for genetic vaccines by ANWER, K, EARLE, K. A, ROLLAND, A. P, MEI SHI, JIJUN WANG, MUMPER, R. J, PROCTOR, B, JANSA, K, LEDEBUR, H. C, DAVIS, S, EAGLSTEIN, W

“…A plasmid-based gene expression system was complexed with protective, interactive, and non-condensing (PINC) polymer system and administered with Medi-Jector,…”
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Transcriptional regulation of the intercellular adhesion molecule-1 gene by inflammatory cytokines in human endothelial cells. Essential roles of a variant NF-kappa B site and p65 homodimers by Ledebur, H C, Parks, T P

“…Intercellular adhesion molecule-1 (ICAM-1) is greatly up-regulated on endothelial cells at sites of inflammation and is involved in leukocyte attachment and…”
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A prion protein epitope selective for the pathologically misfolded conformation by Cashman, Neil R, Paramithiotis, Eustache, Pinard, Marc, Lawton, Trebor, LaBoissiere, Sylvie, Leathers, Valerie L, Zou, Wen-Quan, Estey, Lisa A, Lamontagne, Julie, Lehto, Marty T, Kondejewski, Leslie H, Francoeur, Gregory P, Papadopoulos, Maria, Haghighat, Ashkan, Spatz, Stephen J, Head, Mark, Will, Robert, Ironside, James, O'Rourke, Katherine, Tonelli, Quentin, Ledebur, Harry C, Chakrabartty, Avi

“…Conformational conversion of proteins in disease is likely to be accompanied by molecular surface exposure of previously sequestered amino-acid side chains. We…”
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A mammalian artificial chromosome engineering system (ACE System) applicable to biopharmaceutical protein production, transgenesis and gene-based cell therapy by Lindenbaum, Michael, Perkins, Ed, Csonka, Erika, Fleming, Elena, Garcia, Lisa, Greene, Amy, Gung, Lindsay, Hadlaczky, Gyula, Lee, Edmond, Leung, Josephine, MacDonald, Neil, Maxwell, Alexisann, Mills, Kathleen, Monteith, Diane, Perez, Carl F., Shellard, Joan, Stewart, Sandy, Stodola, Tom, Vandenborre, Dana, Vanderbyl, Sandy, Ledebur, Harry C.

“…Mammalian artificial chromosomes (MACs) provide a means to introduce large payloads of genetic information into the cell in an autonomously replicating,…”
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Transgene expression after stable transfer of a mammalian artificial chromosome into human hematopoietic cells by Vanderbyl, Sandra L., Sullenbarger, Brent, White, Nicole, Perez, Carl F., MacDonald, G. Neil, Stodola, Tom, Bunnell, Bruce A., Ledebur, Harry C., Lasky, Larry C.

“…The transfer of mammalian artificial chromosomes (MACs) to hematopoietic stem and progenitor cells (HSPCs) presents a promising new strategy for ex vivo gene…”
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Development of mammalian artificial chromosomes for the treatment of genetic diseases: Sandhoff and Krabbe diseases by Bunnell, Bruce A, Izadpanah, Reza, Ledebur, Jr, Harry C, Perez, Carl F

“…Mammalian artificial chromosomes (MACs) are being developed as alternatives to viral vectors for gene therapy applications, as they allow for the introduction…”
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