Search Results - "Ledda, Lorenzo"
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Closed-Form Exact Solution for Free Vibration Analysis of Symmetric Functionally Graded Beams
Published in Symmetry (Basel) (01-09-2024)“…The dynamic stiffness method is developed to analyze the natural vibration characteristics of functionally graded beams, where material properties change…”
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Uncovering the expression of circPVT1 in the extracellular vesicles of acute myeloid leukemia patients
Published in Biomedicine & pharmacotherapy (01-09-2023)“…Extracellular vesicles (EVs) act as molecular mediators in the tumor microenvironment, by shuttling information contained within malignant cells and…”
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P451: GENE FUSIONS AND OTHER GENOMIC EVENTS UNDERLIE VENETOCLAX AND HYPOMETHYLATING AGENT RESISTANCE AND PROVIDE NEW TARGETS IN ACUTE MYELOID LEUKEMIA
Published in HemaSphere (08-08-2023)Get full text
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Novel Mechanisms of Venetoclax Resistance in Acute Myeloid Leukemia Based on Genomic Rearrangements
Published in Blood (02-11-2023)“…Introduction: Venetoclax (VEN), a BCL-2 inhibitor, effectively induces apoptosis in acute myeloid leukemia (AML) cells. Resistance to VEN in the treatment of…”
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Exploring the ATR-CHK1 pathway in the response of doxorubicin-induced DNA damages in acute lymphoblastic leukemia cells
Published in Cell biology and toxicology (01-06-2023)“…Doxorubicin (Dox) is one of the most commonly used anthracyclines for the treatment of solid and hematological tumors such as B−/T cell acute lymphoblastic…”
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Correction to: Exploring the ATR-CHK1 pathway in the response of doxorubicin-induced DNA damages in acute lymphoblastic leukemia cells
Published in Cell biology and toxicology (31-08-2024)Get full text
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Abstract 1555: circPVT1 and linear PVT1 isoforms regulate cell growth, metabolic and DNA damage response related gene signatures in acute myeloid leukemia
Published in Cancer research (Chicago, Ill.) (15-06-2022)“…Abstract Non-coding (nc)RNAs, including circular (circ)RNAs, contribute to tumor development and progression. Several ncRNAs were shown to affect the onset,…”
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Abstract 5956: FLT3 alterations and inhibition in triple negative B-cell adult acute lymphoblastic leukemia patients
Published in Cancer research (Chicago, Ill.) (22-03-2024)“…Abstract Backgroud: The prognosis of B cell ALL patients (pts) relapsing after Hematopoietic Transplant is poor and new drugs are needed. In acute myeloid…”
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Abstract 3001: Targeting autophagy in acute lymphoblastic leukemia: Synergism between ponatinib, hydroxychloroquine and rapamycin
Published in Cancer research (Chicago, Ill.) (15-06-2022)“…Abstract Currently, the role of autophagy in acute lymphoblastic leukemia (ALL) is not fully understood however it has been linked to drug resistance. Several…”
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Abstract 5788: Genomic and transcriptomic profiles of DNA damage response genes in acute myeloid leukemia
Published in Cancer research (Chicago, Ill.) (15-06-2022)“…Abstract The DNA damage response (DDR) pathway is frequently deregulated in cancer and it represent an attractive therapeutic opportunity. In acute myeloid…”
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Abstract 3804: Linear PVT1 isoforms and circPVT1 regulate DNA damage response and immunological pathways in acute myeloid leukemia and have a potential role in the crosstalk between leukemic cells and the tumor microenvironment
Published in Cancer research (Chicago, Ill.) (04-04-2023)“…Abstract The human Plasmacytoma Variant Translocation 1 (PVT1) gene encodes for 176 linear (PVT1, lncipedia.org) and 29 circular isoforms (circPVT1,…”
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