Search Results - "Ledda, F"

Architecture and regulation of a GDNF-GFRα1 synaptic adhesion assembly by Houghton, F. M., Adams, S. E., Ríos, A. S., Masino, L., Purkiss, A. G., Briggs, D. C., Ledda, F., McDonald, N. Q.

“…Glial-cell line derived neurotrophic factor (GDNF) bound to its co-receptor GFRα1 stimulates the RET receptor tyrosine kinase, promoting neuronal survival and…”
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Analysis Framework for Nuclear Heating Effects on HTS-Based Conductors in Fusion Power Plants by Sparacio, S., Viarengo, S., Ledda, F., Torsello, D., Riva, N., Hartwig, Z. S., Savoldi, L., Laviano, F.

“…High-temperature superconducting-slotted cables, including the VIPER cable, are being investigated as possible candidates for winding the toroidal field coils…”
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Molecular pathways triggered by COVID-19 in different organs: ACE2 receptor-expressing cells under attack? A review by Saba, L, Gerosa, C, Fanni, D, Marongiu, F, La Nasa, G, Caocci, G, Barcellona, D, Balestrieri, A, Coghe, F, Orru, G, Coni, P, Piras, M, Ledda, F, Suri, J S, Ronchi, A, D'Andrea, F, Cau, R, Castagnola, M, Faa, G

“…In human pathology, SARS-CoV-2 utilizes multiple molecular pathways to determine structural and biochemical changes within the different organs and cell types…”
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Acyl-CoA binding protein (ACBP) is highly expressed in the developing human kidney by Piras, M, Gerosa, C, Fanni, D, Cau, F, Coni, P, Murru, R, Denotti, G, Orrù, G, Scano, A, Ledda, F, Van Eyken, P, Coghe, F, Faa, G, Castagnola, M

“…Acyl-CoA-binding protein (ACBP), also known as diazepam binding inhibitor (DBI), is a small phylogenetically conserved protein. This ancestral peptide is…”
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3D Analysis of magnetic field lines to assess the impact of stray fields at breakdown in ITER by Formisano, A., Albanese, R., Ambrosino, G., de Magistris, M., De Vries, P., Gribov, Y., Ledda, F., Martone, R., Mattei, M., Minucci, S., Pironti, A., Pizzo, F., Snipes, J., Villone, F., Zabeo, L.

“…•Lines tracing for 3D magnetic fields is discussed.•ITER breakdown field in presence of coils manufacturing and assembly tolerances is taken as a test…”
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Biodiversity assessment in Western Mediterranean marine protected areas (MPAs): Porifera of Posidonia oceanica meadows (Asinara Island MPA) and marine caves (Capo Caccia-Isola Piana MPA) of Sardinia by Padiglia, A., Cadeddu, B., Ledda, F. D., Bertolino, M., Costa, G., Pronzato, R., Manconi, R.

“…This paper focuses on a faunistic inventory and the biogeographic pattern of Sardinian Porifera in a scarcely investigated Italian sea belonging to the Eastern…”
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The bradykinin/B1 receptor promotes angiogenesis by up‐regulation of endogenous FGF‐2 in endothelium via the nitric oxide synthase pathway by Parenti, Astrid, Morbidelli, Lucia, Ledda, Fabrizio, Granger, Harris J., Ziche, Marina

“…ABSTRACT Bradykinin (BK) mediates inflammation and contributes to angiogenesis. We assessed the mechanisms for BK contribution to angiogenesis. Nanomolar…”
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Nitric oxide mediates mitogenic effect of VEGF on coronary venular endothelium by Morbidelli, L, Chang, C H, Douglas, J G, Granger, H J, Ledda, F, Ziche, M

“…Vascular endothelial growth factor (VEGF) is a secreted protein that is a specific growth factor for endothelial cells. We have recently demonstrated that…”
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Tubulin posttranslational modifications induced by cadmium in the sponge Clathrina clathrus by Ledda, F.D., Ramoino, P., Ravera, S., Perino, E., Bianchini, P., Diaspro, A., Gallus, L., Pronzato, R., Manconi, R.

“…•The effect of Cd2+ on Clathrina clathrus microtubule network was studied.•Cd2+ exposure increases acetylated and detyrosinated α-tubulin levels.•Microtubules…”
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Erectile dysfunction: from biochemical pharmacology to advances in medical therapy by Maggi, M, Filippi, S, Ledda, F, Magini, A, Forti, G

“…Research on penile smooth muscle physiology has increased the number of drugs available for treating erectile dysfunction (ED). Penile erection involves the…”
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Identification, localization and functional activity of oxytocin receptors in epididymis by Filippi, S, Vannelli, G.B, Granchi, S, Luconi, M, Crescioli, C, Mancina, R, Natali, A, Brocchi, S, Vignozzi, L, Bencini, E, Noci, I, Ledda, F, Forti, G, Maggi, Mario

“…Oxytocin (OT) is a neurohypophysial hormone with unclear physiological functions in the male. Several previous studies indicated that OT might have a role in…”
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Sponges of marine caves: Notes on the status of the Mediterranean palaeoendemic Petrobiona massiliana (Porifera: Calcarea: Lithonida) with new records from Sardinia by Manconi, R., Ledda, F. D., Serusi, A., Corso, G., Stocchino, G. A.

“…The discovery of conspicuous populations of the rare species Petrobiona massiliana is reported from shallow water karstic caves of Sardinia. The morphological…”
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Expression and regulation of endothelin-1 and its receptors in human penile smooth muscle cells by Granchi, S., Vannelli, G.B., Vignozzi, L., Crescioli, C., Ferruzzi, P., Mancina, R., Vinci, M.C., Forti, G., Filippi, S., Luconi, M., Ledda, F., Maggi, M.

“…We report for the first time that penile smooth muscle cells (SMC) not only respond to, but also synthesize, endothelin-1 (ET-1), one of the main regulators of…”
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Role of oxytocin in the ejaculatory process by FILIPPI, S, VIGNOZZI, L, VANNELLI, G. B, LEDDA, F, FORTI, G, MAGGI, M

“…Oxytocin (OT) is a neurohypophysial hormone with overall unclear physiological functions in the male. Several studies indicated that OT has a key role in the…”
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Effects of hypoxia on endothelin‐1 sensitivity in the corpus cavernosum by Filippi, S., Marini, M., Vannelli, G.B., Crescioli, C., Granchi, S., Vignozzi, L., Luconi, M., Ferruzzi, P., Morelli, A., Forti, G., Ledda, F., Maggi, M.

“…The penis remains in a hypo‐oxygenated, flaccid state for a large majority of the time. In this study, we investigated the effect of changing oxygen tension on…”
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Nitric oxide promotes DNA synthesis and cyclic GMP formation in endothelial cells from postcapillary venules by Ziche, M, Morbidelli, L, Masini, E, Granger, H, Geppetti, P, Ledda, F

“…The nitric oxide (NO)-generating drug sodium nitroprusside (SNP) has been assayed on DNA synthesis in cultured endothelial cells isolated from coronary…”
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IL-10 expression by CT26 colon carcinoma cells inhibits their malignant phenotype and induces a T cell-mediated tumor rejection in the context of a systemic Th2 response by ADRIS, S. K, KLEIN, S, JASNIS, M. A, CHULUYAN, E, LEDDA, M. F, BRAVO, A. I, CARBONE, C, CHERNAJOVSKY, Y, PODHAJCER, O. L

“…In spite of the evidence that IL-10 has Th1-immunosuppressive and anti-inflammatory effects, it has been shown that IL-10 may reduce the tumorigenic capacity…”
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GDNF and GFRα: a versatile molecular complex for developing neurons by Paratcha, Gustavo, Ledda, Fernanda

“…The GDNF family ligands (GFLs) signal through the canonical signaling receptor Ret and a glycosyl-phosphatidylinositol-anchored co-receptor, GFRα. In recent…”
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Endothelium-dependency of yohimbine-induced corpus cavernosum relaxation by FILIPPI, S, LUCONI, M, GRANCHI, S, NATALI, A, TOZZI, P, FORTI, G, LEDDA, F, MAGGI, M

“…Development and maintenance of penile erection requires the relaxation of the smooth muscle cells in the cavernous bodies and is essentially mediated by nitric…”
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Hypergravity Effects on Dendritic Cells and Vascular Wall Interactions by Bellik, L., Parenti, A., Ledda, F., Basile, V., Romano, G., Fusi, F., Monici, M.

“…Dendritic cells (DCs), the most potent antigen-presenting cells inducing specific immune responses, are involved in the pathogenesis of atherosclerosis. In…”
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