Search Results - "Lecureur, V"

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    Alterations of intracellular pH homeostasis in apoptosis: origins and roles by Lagadic-Gossmann, D, Huc, L, Lecureur, V

    Published in Cell death and differentiation (01-09-2004)
    “…Intracellular pH (pHi) has an important role in the maintenance of normal cell function, and hence this parameter has to be tightly controlled within a narrow…”
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    Drug‐induced granulomatosis: is dupilumab the new kid on the block? by Belhomme, N., Gaignon, T., Jouneau, S., Misery, L., Abasq‐Thomas, C., Cador, B., Lecureur, V., Cadiou, S., Ballerie, A., Polard, E., Mensi, S., Jego, P., Lescoat, A.

    “…Dupilumab is an IgG4 antibody directed toward IL-4 and IL-13, two major effectors of the Th2 immunity response. It was originally developed for severe and/or…”
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    Mechanisms involved in lipid accumulation and apoptosis induced by 1-nitropyrene in Hepa1c1c7 cells by Podechard, N., Tekpli, X., Catheline, D., Holme, J.A., Rioux, V., Legrand, P., Rialland, M., Fardel, O., Lagadic-Gossmann, D., Lecureur, V.

    Published in Toxicology letters (30-10-2011)
    “…► 1-Nitropyrene increases apoptosis and lipid accumulation in hepatoma cells. ► 1-NP modifies cholesterol and fatty acids content. ► 1-NP alters the expression…”
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    Rifampicin enhances anti-cancer drug accumulation and activity in multidrug-resistant cells by Fardel, Olivier, Lecureur, Valérie, Loyer, Pascal, Guillouzo, André

    Published in Biochemical pharmacology (11-05-1995)
    “…Rifampicin, a semi-synthetic antibiotic used in the treatment of tuberculosis and belonging to the chemical class of rifamycins, was examined for its effect on…”
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    Interleukin-8 induction by the environmental contaminant benzo(a)pyrene is aryl hydrocarbon receptor-dependent and leads to lung inflammation by Podechard, Normand, Lecureur, Valérie, Le Ferrec, Eric, Guenon, Isabelle, Sparfel, Lydie, Gilot, David, Gordon, John R., Lagente, Vincent, Fardel, Olivier

    Published in Toxicology letters (15-03-2008)
    “…Benzo(a)pyrene (BP) is an environmental contaminant known to favor airway inflammation likely through up-regulation of pro-inflammatory cytokines. The present…”
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    Altération des capacités d’efferocytose des macrophages dérivés de monocytes différenciés par CXCL4 et implications dans la sclérodermie systémique by Le Tallec, E., Bellamri, N., Lelong, M., Frenger, Q., Lescoat, A., Gros, F., Lecureur, V.

    Published in La revue de medecine interne (01-06-2022)
    “…La sclérodermie systémique (SSc) est une maladie auto-immune caractérisée par l’existence d’anticorps antinucléaires. Leur production peut être liée à un excès…”
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    L’amélioration de la fibrose pulmonaire et cutanée dans le modèle murin de bléomycine SSC-ILD par le ruxolitinib n’est pas liée à la capacité d’efferocytose des macrophages by Bellamri, N., Lelong, M., Le Tallec, E., Joannes, A., Lescoat, A., Lecureur, V.

    Published in La revue de medecine interne (01-06-2022)
    “…La sclérodermie systémique (SSc) est caractérisée par la production d’anticorps antinucléaires (ANA) qui pourraient être liés à un excès de cellules…”
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    Impact thérapeutique des cellules stromales mésenchymateuses adipocytaires sur les sous-populations myéloïdes dans des modèles murins de sclérodermie by Zimmermann, F., Morin, L., Marie, L., Gauthier, J., Séverine, L., Dessauge, E., Lejeune, T., Delaloy, C., Tarte, K., Lescoat, A., Lecureur, V.

    Published in La revue de medecine interne (01-06-2023)
    “…La sclérodermie systémique (SSc) est une maladie auto-immune rare, caractérisée par des manifestations fibrosantes notamment cutanées et pulmonaires. L’arsenal…”
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    NPC1 repression contributes to lipid accumulation in human macrophages exposed to environmental aryl hydrocarbons by Podechard, Normand, Le Ferrec, Eric, Rebillard, Amélie, Fardel, Olivier, Lecureur, Valérie

    Published in Cardiovascular research (01-05-2009)
    “…Aims Aryl hydrocarbons (AHs), such as 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and benzo(a)pyrene (BP), are environmental contaminants promoting the…”
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    Inhibition of human mesenchymal stem cell-derived adipogenesis by the environmental contaminant benzo(a)pyrene by Podechard, Normand, Fardel, Olivier, Corolleur, Michel, Bernard, Marc, Lecureur, Valérie

    Published in Toxicology in vitro (01-09-2009)
    “…Polycyclic aromatic hydrocarbons (PAHs) such as benzo(a)pyrene (BP) are environmental contaminants exerting various toxic effects. PAHs have notably been found…”
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    Mechanisms involved in lipid accumulation and apoptosis induced by 1-nitropyrene in Hepa1c1c7 cells by Podechard, N., Tekpli, X., Catheline, Daniel D., Holme, J. A., Rioux, Vincent V., Legrand, Philippe P., Rialland, M., Fardel, O., Lagadic-Gossmann, D., Lecureur, V.

    Published in Toxicology letters (30-10-2011)
    “…1-Nitropyrene (1-NP) is a nitro-polycyclic aromatic hydrocarbon (nitro-PAH) present in diesel exhaust and bound to particular matter in urban air. We show that…”
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